適用於公開取用強制性政策的文章 - David E. Shaw瞭解詳情
未在任何資料庫公開的文章：2
Structural basis of AZD9291 selectivity for EGFR T790M
XE Yan, P Ayaz, SJ Zhu, P Zhao, L Liang, CH Zhang, YC Wu, JL Li, ...
Journal of medicinal chemistry 63 (15), 8502-8511, 2020
授權規定： National Natural Science Foundation of China
Insights into kinetic mechanism of Janus kinase 3 and its inhibition by tofacitinib
M Hekmatnejad, S Conwell, SM Lok, A Kutach, D Shaw, E Fang, ...
Archives of Biochemistry and Biophysics 612, 22-34, 2016
授權規定： US National Institutes of Health
在某個資料庫公開的文章：52
Atomic-level characterization of the structural dynamics of proteins
DE Shaw, P Maragakis, K Lindorff-Larsen, S Piana, RO Dror, ...
Science 330 (6002), 341-346, 2010
授權規定： US National Institutes of Health
Structure and dynamics of the M3 muscarinic acetylcholine receptor
AC Kruse, J Hu, AC Pan, DH Arlow, DM Rosenbaum, E Rosemond, ...
Nature 482 (7386), 552-556, 2012
授權規定： US National Institutes of Health
Structure and function of an irreversible agonist-β2 adrenoceptor complex
DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ...
Nature 469 (7329), 236-240, 2011
授權規定： US National Institutes of Health, Science Foundation Ireland
The dynamic process of β2-adrenergic receptor activation
R Nygaard, Y Zou, RO Dror, TJ Mildorf, DH Arlow, A Manglik, AC Pan, ...
Cell 152 (3), 532-542, 2013
授權規定： US National Institutes of Health
How does a drug molecule find its target binding site?
Y Shan, ET Kim, MP Eastwood, RO Dror, MA Seeliger, DE Shaw
Journal of the American Chemical Society 133 (24), 9181-9183, 2011
授權規定： US National Institutes of Health
Architecture and membrane interactions of the EGF receptor
A Arkhipov, Y Shan, R Das, NF Endres, MP Eastwood, DE Wemmer, ...
Cell 152 (3), 557-569, 2013
授權規定： US National Institutes of Health, Howard Hughes Medical Institute, Canadian …
High-resolution crystal structure of human protease-activated receptor 1
C Zhang, Y Srinivasan, DH Arlow, JJ Fung, D Palmer, Y Zheng, HF Green, ...
Nature 492 (7429), 387-392, 2012
授權規定： US National Institutes of Health
Conformational coupling across the plasma membrane in activation of the EGF receptor
NF Endres, R Das, AW Smith, A Arkhipov, E Kovacs, Y Huang, JG Pelton, ...
Cell 152 (3), 543-556, 2013
授權規定： US National Institutes of Health, Howard Hughes Medical Institute, Canadian …
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs
RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ...
Nature 503 (7475), 295-299, 2013
授權規定： National Health and Medical Research Council, Australia
Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization
Y Shan, MP Eastwood, X Zhang, ET Kim, A Arkhipov, RO Dror, J Jumper, ...
Cell 149 (4), 860-870, 2012
授權規定： US National Institutes of Health
Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3
N Jura, Y Shan, X Cao, DE Shaw, J Kuriyan
Proceedings of the National Academy of Sciences 106 (51), 21608-21613, 2009
授權規定： US National Institutes of Health, Howard Hughes Medical Institute
Structural basis for nucleotide exchange in heterotrimeric G proteins
RO Dror, TJ Mildorf, D Hilger, A Manglik, DW Borhani, DH Arlow, ...
Science 348 (6241), 1361-1365, 2015
授權規定： US National Institutes of Health, UK Biotechnology and Biological Sciences …
A conserved protonation-dependent switch controls drug binding in the Abl kinase
Y Shan, MA Seeliger, MP Eastwood, F Frank, H Xu, MØ Jensen, RO Dror, ...
Proceedings of the National Academy of Sciences 106 (1), 139-144, 2009
授權規定： US National Institutes of Health
Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F
RM Bandaranayake, D Ungureanu, Y Shan, DE Shaw, O Silvennoinen, ...
Nature structural & molecular biology 19 (8), 754-759, 2012
授權規定： US National Institutes of Health
Mechanism of NMDA receptor channel block by MK-801 and memantine
X Song, MØ Jensen, V Jogini, RA Stein, CH Lee, HS Mchaourab, ...
Biophysical Journal 114 (3), 24a-25a, 2018
授權規定： US Department of Energy, US National Institutes of Health, Howard Hughes …
Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody
AG Schmidt, H Xu, AR Khan, T O’Donnell, S Khurana, LR King, ...
Proceedings of the National Academy of Sciences 110 (1), 264-269, 2013
授權規定： US National Institutes of Health, Howard Hughes Medical Institute
Microsecond molecular dynamics simulation shows effect of slow loop dynamics on backbone amide order parameters of proteins
P Maragakis, K Lindorff-Larsen, MP Eastwood, RO Dror, JL Klepeis, ...
The Journal of Physical Chemistry B 112 (19), 6155-6158, 2008
授權規定： US National Institutes of Health
Structural origin of slow diffusion in protein folding
HS Chung, S Piana-Agostinetti, DE Shaw, WA Eaton
Science 349 (6255), 1504-1510, 2015
授權規定： US National Institutes of Health
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