IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA M Calfon, H Zeng, F Urano, JH Till, SR Hubbard, HP Harding, SG Clark, ... Nature 415 (6867), 92-96, 2002 | 3347 | 2002 |
Protein tyrosine kinase structure and function SR Hubbard, JH Till Annual review of biochemistry 69 (1), 373-398, 2000 | 1656 | 2000 |
Crystal structure of the tyrosine kinase domain of the human insulin receptor SR Hubbard, L Wei, L Ellis, WA Hendrickson Nature 372, 22, 1994 | 1478 | 1994 |
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors M Mohammadi, G McMahon, L Sun, C Tang, P Hirth, BK Yeh, ... Science 276 (5314), 955-960, 1997 | 1370 | 1997 |
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog SR Hubbard The EMBO journal, 1997 | 1281 | 1997 |
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling Z Songyang, KL Carraway III, MJ Eck, SC Harrison, RA Feldman, ... Nature 373 (6514), 536-539, 1995 | 1166 | 1995 |
Structural basis for FGF receptor dimerization and activation AN Plotnikov, J Schlessinger, SR Hubbard, M Mohammadi Cell 98 (5), 641-650, 1999 | 825 | 1999 |
Lrp4 is a receptor for Agrin and forms a complex with MuSK N Kim, AL Stiegler, TO Cameron, PT Hallock, AM Gomez, JH Huang, ... Cell 135 (2), 334-342, 2008 | 747 | 2008 |
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors AD Laird, P Vajkoczy, LK Shawver, A Thurnher, C Liang, M Mohammadi, ... Cancer Research 60 (15), 4152-4160, 2000 | 701 | 2000 |
Receptor tyrosine kinases: mechanisms of activation and signaling SR Hubbard, WT Miller Current opinion in cell biology 19 (2), 117-123, 2007 | 697 | 2007 |
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain M Mohammadi, S Froum, JM Hamby, MC Schroeder, RL Panek, GH Lu, ... The EMBO journal, 1998 | 628 | 1998 |
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity AN Plotnikov, SR Hubbard, J Schlessinger, M Mohammadi Cell 101 (4), 413-424, 2000 | 559 | 2000 |
Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism M Mohammadi, J Schlessinger, SR Hubbard Cell 86 (4), 577-587, 1996 | 538 | 1996 |
Autoregulatory mechanisms in protein-tyrosine kinases SR Hubbard, M Mohammadi, J Schlessinger Journal of Biological Chemistry 273 (20), 11987-11990, 1998 | 480 | 1998 |
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase S Favelyukis, JH Till, SR Hubbard, WT Miller Nature structural biology 8 (12), 1058-1063, 2001 | 450 | 2001 |
Juxtamembrane autoinhibition in receptor tyrosine kinases SR Hubbard Nature Reviews Molecular Cell Biology 5 (6), 464-471, 2004 | 413 | 2004 |
Structural analysis of receptor tyrosine kinases SR Hubbard Progress in biophysics and molecular biology 71 (3-4), 343-358, 1999 | 361 | 1999 |
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling D Ungureanu, J Wu, T Pekkala, Y Niranjan, C Young, ON Jensen, CF Xu, ... Nature structural & molecular biology 18 (9), 971-976, 2011 | 339 | 2011 |
How IRE1 reacts to ER stress D Ron, SR Hubbard Cell 132 (1), 24-26, 2008 | 295 | 2008 |
Mechanism-based design of a protein kinase inhibitor K Parang, JH Till, AJ Ablooglu, RA Kohanski, SR Hubbard, PA Cole Nature structural biology 8 (1), 37-41, 2001 | 290 | 2001 |