Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans DJ Carlile, N Hakooz, MK Bayliss, JB Houston British journal of clinical pharmacology 47 (6), 625-635, 1999 | 148 | 1999 |
Determination of a Human Hepatic Microsomal Scaling Factor for Predicting in Vivo Drug Clearance N Hakooz, K Ito, H Rawden, H Gill, L Lemmers, AR Boobis, RJ Edwards, ... Pharmaceutical research 23, 533-539, 2006 | 83 | 2006 |
Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers N Hakooz, I Hamdan Current drug metabolism 8 (1), 9-15, 2007 | 76 | 2007 |
Prediction of metabolic clearance using cryopreserved human hepatocytes: kinetic characteristics for five benzodiazepines D Hallifax, HC Rawden, N Hakooz, JB Houston Drug metabolism and disposition 33 (12), 1852-1858, 2005 | 75 | 2005 |
Allele and genotype frequencies of the polymorphic cytochrome P450 genes (CYP1A1, CYP3A4, CYP3A5, CYP2C9 and CYP2C19) in the Jordanian population AM Yousef, NR Bulatova, W Newman, N Hakooz, S Ismail, H Qusa, ... Molecular biology reports 39, 9423-9433, 2012 | 71 | 2012 |
Caffeine metabolic ratios for the in vivo evaluation of CYP1A2, N-acetyltransferase 2, xanthine oxidase and CYP2A6 enzymatic activities NMK Hakooz Current drug metabolism 10 (4), 329-338, 2009 | 64 | 2009 |
Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated … DJ Carlile, N Hakooz, JB Houston Drug metabolism and disposition 27 (4), 526-532, 1999 | 38 | 1999 |
Genetic polymorphism of CYP2C19 in a Jordanian population: influence of allele frequencies of CYP2C19*1 and CYP2C19*2 on the pharmacokinetic profile of … I Zalloum, N Hakooz, T Arafat Molecular biology reports 39, 4195-4200, 2012 | 32 | 2012 |
Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population N Hakooz, T Arafat, D Payne, W Ollier, S Pushpakom, J Andrews, ... European journal of clinical pharmacology 66, 999-1003, 2010 | 32 | 2010 |
CNV analysis associates AKNAD1 with type-2 diabetes in Jordan subpopulations R Dajani, J Li, Z Wei, JT Glessner, X Chang, CJ Cardinale, R Pellegrino, ... Scientific reports 5 (1), 13391, 2015 | 28 | 2015 |
Diabetes mellitus in genetically isolated populations in Jordan: prevalence, awareness, glycemic control, and associated factors R Dajani, YS Khader, R Fatahallah, M El-Khateeb, AH Shiyab, N Hakooz Journal of Diabetes and its Complications 26 (3), 175-180, 2012 | 25 | 2012 |
Effects of the genetic variants of organic cation transporters 1 and 3 on the pharmacokinetics of metformin in Jordanians. AT Hakooz Nancy, Jarrar Yazun, Zihlif Malek, Imraish Amer, Hamed Saja Drug Metabolism and Personalized Therapy 32 (3), 157-162, 2017 | 23 | 2017 |
Metabolic syndrome between two ethnic minority groups (Circassians and Chechens) and the original inhabitants of Jordan R Dajani, YS Khader, N Hakooz, R Fatahalla, F Quadan Endocrine 43, 112-119, 2013 | 23 | 2013 |
SLC30A8 gene polymorphism rs13266634 associated with increased risk for developing type 2 diabetes mellitus in Jordanian population S Mashal, M Khanfar, S Al-Khalayfa, L Srour, L Mustafa, NM Hakooz, ... Gene 768, 145279, 2021 | 22 | 2021 |
Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation. HN Al-Sha'er MA, Mansi I, Almazari I J Mol Graph Model 62, 213-225, 2015 | 22 | 2015 |
Metformin IR versus XR pharmacokinetics in humans N Idkaidek, T Arafat, M Melhim, J Alawneh, N Hakooz J Bioequiv Availab 3 (10), 10.4172, 2011 | 21 | 2011 |
High-performance liquid chromatographic determination of montelukast sodium in human plasma: application to bioequivalence study AK Shakya, TA Arafat, NM Hakooz, AN Abuawwad, H Al-Hroub, M Melhim Acta Chromatographica 26 (3), 457-472, 2014 | 17 | 2014 |
Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations R Dajani, J Li, Z Wei, ME March, Q Xia, Y Khader, N Hakooz, R Fatahallah, ... PeerJ 5, e3618, 2017 | 16 | 2017 |
UDP-glucuronosyltransferase 1A4 (UGT1A4) polymorphisms in a Jordanian population N Hakooz, S Alzubiedi, AM Yousef, T Arafat, R Dajani, N Ababneh, ... Molecular Biology Reports 39, 7763-7768, 2012 | 16 | 2012 |
Prevalence of MTHFR C677T Single Nucleotide Polymorphism in Genetically Isolated Populations in Jordan R Dajani, R Fathallah, A Arafat, ME AbdulQader, N Hakooz, ... Biochemical genetics 51, 780-788, 2013 | 14 | 2013 |