Lewis Cantley

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John AsaraAssociate Professor Medicine, Harvard Medical School; Director, Beth Israel Deaconess Medical Center在 bidmc.harvard.edu 的電子郵件地址已通過驗證
Costas LyssiotisProfessor of Physiology, University of Michigan在 lyssiotis.com 的電子郵件地址已通過驗證
Ji LuoNational Cancer Institute在 nih.gov 的電子郵件地址已通過驗證
David FrumanProfessor of Molecular Biology & Biochemistry, UC Irvine在 uci.edu 的電子郵件地址已通過驗證
John BlenisProfessor of Pharmacology, Weill Cornell Medicine在 med.cornell.edu 的電子郵件地址已通過驗證
Alex Toker在 bidmc.harvard.edu 的電子郵件地址已通過驗證
Jason LocasaleDuke University在 alum.mit.edu 的電子郵件地址已通過驗證
Brendan D. ManningHarvard University在 hsph.harvard.edu 的電子郵件地址已通過驗證
Lucia Rameh PlantVanderbilt University在 vanderbilt.edu 的電子郵件地址已通過驗證
C. Ronald KahnJoslin Diabetes Center and Harvard Medical School在 joslin.harvard.edu 的電子郵件地址已通過驗證
Reuben ShawThe Salk Institute of Biological Studies在 salk.edu 的電子郵件地址已通過驗證
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical Center在 bidmc.harvard.edu 的電子郵件地址已通過驗證
Ronald A. DePinhoMD Anderson在 mdanderson.org 的電子郵件地址已通過驗證
David R. KaplanHospital for Sick Children在 sickkids.ca 的電子郵件地址已通過驗證
Steven ShoelsonHarvard Medical School在 joslin.harvard.edu 的電子郵件地址已通過驗證
Gerburg WulfAssociate Professor in Medicine, Harvard Medical School在 bidmc.harvard.edu 的電子郵件地址已通過驗證
Kurt AugerGSK在 gsk.com 的電子郵件地址已通過驗證
Pasi JanneDana Farber Cancer Institute在 dfci.harvard.edu 的電子郵件地址已通過驗證
Malcolm WhitmanHarvard在 hms.harvard.edu 的電子郵件地址已通過驗證
Marcus D GoncalvesWeill Cornell New York Presbyterian Hospital在 med.cornell.edu 的電子郵件地址已通過驗證

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Lewis Cantley

Dana Farber Cancer Center and Harvard Medical School

在 med.cornell.edu 的電子郵件地址已通過驗證

cancer metabolism signal transduction PI 3-Kinase Protein kinases


標題按引用次數排序按年份排序按標題排序	引用次數引用次數	年份
Understanding the Warburg effect: the metabolic requirements of cell proliferation MG Vander Heiden, LC Cantley, CB Thompson science 324 (5930), 1029-1033, 2009	17108	2009
AKT/PKB signaling: navigating downstream BD Manning, LC Cantley Cell 129 (7), 1261-1274, 2007	7488	2007
The phosphoinositide 3-kinase pathway LC Cantley Science 296 (5573), 1655-1657, 2002	7389	2002
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ... science 316 (5827), 1039-1043, 2007	5522	2007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ... Nature 462 (7274), 739-744, 2009	4792	2009
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism JA Engelman, J Luo, LC Cantley Nature Reviews Genetics 7 (8), 606-619, 2006	4042	2006
Oncogenes and signal transduction LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ... Cell 64 (2), 281-302, 1991	3583	1991
SH2 domains recognize specific phosphopeptide sequences S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ... Cell 72 (5), 767-778, 1993	3574	1993
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230-233, 2008	3236	2008
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011	2891*	2011
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway LC Cantley, BG Neel Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999	2764	1999
Ras, PI (3) K and mTOR signalling controls tumour cell growth RJ Shaw, LC Cantley Nature 441 (7092), 424-430, 2006	2661	2006
PI3K pathway alterations in cancer: variations on a theme TL Yuan, LC Cantley Oncogene 27 (41), 5497-5510, 2008	2420	2008
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005	2404	2005
The PI3K pathway in human disease DA Fruman, H Chiu, BD Hopkins, S Bagrodia, LC Cantley, RT Abraham Cell 170 (4), 605-635, 2017	2365	2017
PI3K: downstream AKTion blocks apoptosis TF Franke, DR Kaplan, LC Cantley Cell 88 (4), 435-437, 1997	2203	1997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ... Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004	2170	2004
Phosphoinositide kinases DA Fruman, RE Meyers, LC Cantley Annual review of biochemistry 67 (1), 481-507, 1998	2138	1998
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012	2075	2012
The structural basis for 14-3-3: phosphopeptide binding specificity MB Yaffe, K Rittinger, S Volinia, PR Caron, A Aitken, H Leffers, ... Cell 91 (7), 961-971, 1997	2020	1997

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