Targeting the TGFβ signalling pathway in disease RJ Akhurst, A Hata Nature reviews Drug discovery 11 (10), 790-811, 2012 | 1771 | 2012 |
SMAD proteins control DROSHA-mediated microRNA maturation BN Davis, AC Hilyard, G Lagna, A Hata Nature 454 (7200), 56-61, 2008 | 1677 | 2008 |
Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways G Lagna, A Hata, A Hemmati-Brivanlou, J Massagué Nature 383 (6603), 832-836, 1996 | 1211 | 1996 |
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor A Hata, G Lagna, J Massagué, A Hemmati-Brivanlou Genes & development 12 (2), 186-197, 1998 | 1030 | 1998 |
A human Mad protein acting as a BMP-regulated transcriptional activator F Liu, A Hata, JC Baker, J Doody, J Cárcamo, RM Harland, J Massagué Nature 381 (6583), 620-623, 1996 | 886 | 1996 |
TGF-β signaling from receptors to Smads A Hata, YG Chen Cold Spring Harbor perspectives in biology 8 (9), a022061, 2016 | 863 | 2016 |
Tyrosine kinases Lyn and Syk regulate B cell receptor‐coupled Ca2+ mobilization through distinct pathways. M Takata, H Sabe, A Hata, T Inazu, Y Homma, T Nukada, H Yamamura, ... The EMBO journal 13 (6), 1341-1349, 1994 | 824 | 1994 |
The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. M Kretzschmar, F Liu, A Hata, J Doody, J Massagué Genes & development 11 (8), 984-995, 1997 | 781 | 1997 |
A structural basis for mutational inactivation of the tumour suppressor Smad4 Y Shi, A Hata, RS Lo, J Massagué, NP Pavletich Nature 388 (6637), 87-93, 1997 | 652 | 1997 |
OAZ uses distinct DNA-and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways A Hata, J Seoane, G Lagna, E Montalvo, A Hemmati-Brivanlou, ... Cell 100 (2), 229-240, 2000 | 536 | 2000 |
Determinants of specificity in TGF-β signal transduction YG Chen, A Hata, RS Lo, D Wotton, Y Shi, N Pavletich, J Massagué Genes & development 12 (14), 2144-2152, 1998 | 509 | 1998 |
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 A Hata, RS Lo, D Wotton, G Lagna, J Massagué Nature 388 (6637), 82-87, 1997 | 504 | 1997 |
Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha BN Davis, AC Hilyard, PH Nguyen, G Lagna, A Hata Molecular cell 39 (3), 373-384, 2010 | 493 | 2010 |
Regulation of MicroRNA Biogenesis: A miRiad of mechanisms BN Davis, A Hata Cell Communication and Signaling 7, 1-22, 2009 | 447 | 2009 |
Mechanisms of control of microRNA biogenesis BN Davis-Dusenbery, A Hata The journal of biochemistry 148 (4), 381-392, 2010 | 445 | 2010 |
Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype BN Davis, AC Hilyard, PH Nguyen, G Lagna, A Hata Journal of Biological Chemistry 284 (6), 3728-3738, 2009 | 426 | 2009 |
TGF-β signalling through the Smad pathway J Massaous, A Hata Trends in cell biology 7 (5), 187-192, 1997 | 375 | 1997 |
Down-regulation of Krüppel-like Factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-β and bone … BN Davis-Dusenbery, MC Chan, KE Reno, AS Weisman, MD Layne, ... Journal of Biological Chemistry 286 (32), 28097-28110, 2011 | 310 | 2011 |
Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. H Sabe, A Hata, M Okada, H Nakagawa, H Hanafusa Proceedings of the National Academy of Sciences 91 (9), 3984-3988, 1994 | 301 | 1994 |
Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation BN Davis-Dusenbery, C Wu, A Hata Arteriosclerosis, thrombosis, and vascular biology 31 (11), 2370-2377, 2011 | 288 | 2011 |