| Epigenetic differences arise during the lifetime of monozygotic twins MF Fraga, E Ballestar, MF Paz, S Ropero, F Setien, ML Ballestar, ... Proceedings of the National Academy of Sciences 102 (30), 10604-10609, 2005 | 4507 | 2005 |
| Maftools: efficient and comprehensive analysis of somatic variants in cancer A Mayakonda, DC Lin, Y Assenov, C Plass, HP Koeffler Genome research 28 (11), 1747-1756, 2018 | 3315 | 2018 |
| Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2747 | 2012 |
| Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 2019 | 2012 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1923* | 2020 |
| Aberrant CpG-island methylation has non-random and tumour-type–specific patterns JF Costello, MC Frühwald, DJ Smiraglia, LJ Rush, GP Robertson, X Gao, ... Nature genetics 24 (2), 132-138, 2000 | 1779 | 2000 |
| Methylation matters JF Costello, C Plass Journal of medical genetics 38 (5), 285-303, 2001 | 897 | 2001 |
| Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 798 | 2013 |
| MGMT testing—the challenges for biomarker-based glioma treatment W Wick, M Weller, M Van Den Bent, M Sanson, M Weiler, A Von Deimling, ... Nature Reviews Neurology 10 (7), 372-385, 2014 | 620 | 2014 |
| Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ... Cell stem cell 15 (4), 507-522, 2014 | 602 | 2014 |
| Principles for the post-GWAS functional characterization of cancer risk loci ML Freedman, ANA Monteiro, SA Gayther, GA Coetzee, A Risch, C Plass, ... Nature genetics 43 (6), 513-518, 2011 | 533 | 2011 |
| Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer C Plass, SM Pfister, AM Lindroth, O Bogatyrova, R Claus, P Lichter Nature reviews genetics 14 (11), 765-780, 2013 | 489 | 2013 |
| BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ... Nature medicine 19 (7), 901-908, 2013 | 489 | 2013 |
| Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ... The Lancet Oncology 17 (10), 1386-1395, 2016 | 476 | 2016 |
| Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia A Raval, SM Tanner, JC Byrd, EB Angerman, JD Perko, SS Chen, ... Cell 129 (5), 879-890, 2007 | 459 | 2007 |
| The functional consequences of alternative promoter use in mammalian genomes RV Davuluri, Y Suzuki, S Sugano, C Plass, THM Huang Trends in Genetics 24 (4), 167-177, 2008 | 448 | 2008 |
| Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer J Weischenfeldt, R Simon, L Feuerbach, K Schlangen, D Weichenhan, ... Cancer cell 23 (2), 159-170, 2013 | 400 | 2013 |
| Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer A Krohn, T Diedler, L Burkhardt, PS Mayer, C De Silva, ... The American journal of pathology 181 (2), 401-412, 2012 | 393 | 2012 |
| Mutational dynamics between primary and relapse neuroblastomas A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ... Nature genetics 47 (8), 872-877, 2015 | 385 | 2015 |
| Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia W Blum, RB Klisovic, B Hackanson, Z Liu, S Liu, H Devine, ... Journal of Clinical Oncology 25 (25), 3884-3891, 2007 | 383 | 2007 |
