Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55α regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt YC Kuo, KY Huang, CH Yang, YS Yang, WY Lee, CW Chiang Journal of Biological Chemistry 283 (4), 1882-1892, 2008 | 466 | 2008 |
Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin-3–dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation CW Chiang, G Harris, C Ellig, SC Masters, R Subramanian, S Shenolikar, ... Blood, The Journal of the American Society of Hematology 97 (5), 1289-1297, 2001 | 211 | 2001 |
Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis CW Chiang, C Kanies, KW Kim, WB Fang, C Parkhurst, M Xie, T Henry, ... Molecular and cellular biology 23 (18), 6350-6362, 2003 | 194 | 2003 |
GSK-3β acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis CF Lin, CL Chen, CW Chiang, MS Jan, WC Huang, YS Lin Journal of cell science 120 (16), 2935-2943, 2007 | 177 | 2007 |
BAD/BCL-xL heterodimerization leads to bypass of G0/G1 arrest A Chattopadhyay, CW Chiang, E Yang Oncogene 20 (33), 4507-4518, 2001 | 96 | 2001 |
Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma CJ Yen, YJ Lin, CS Yen, HW Tsai, TF Tsai, KY Chang, WC Huang, PW Lin, ... Public Library of Science 7 (7), e41931, 2012 | 88 | 2012 |
The adenosine transporter of Toxoplasma gondii: identification by insertional mutagenesis, cloning, and recombinant expression CW Chiang, N Carter, WJ Sullivan Jr, RGK Donald, DS Roos, ... Journal of Biological Chemistry 274 (49), 35255-35261, 1999 | 83 | 1999 |
Lithium inhibits ceramide-and etoposide-induced protein phosphatase 2A methylation, Bcl-2 dephosphorylation, caspase-2 activation, and apoptosis CL Chen, CF Lin, CW Chiang, MS Jan, YS Lin Molecular pharmacology 70 (2), 510-517, 2006 | 79 | 2006 |
Anti-angiogenesis mediated by angiostatin K1–3, K1–4 and K1–4.5 YH Chen, HL Wu, C Li, YH Huang, CW Chiang, MP Wu, LW Wu Thrombosis and haemostasis 95 (04), 668-677, 2006 | 72 | 2006 |
The B56γ3 regulatory subunit of protein phosphatase 2A (PP2A) regulates S phase-specific nuclear accumulation of PP2A and the G1 to S transition TY Lee, TY Lai, SC Lin, CW Wu, IF Ni, YS Yang, LY Hung, BK Law, ... Journal of Biological Chemistry 285 (28), 21567-21580, 2010 | 57 | 2010 |
Insertional tagging of at least two loci associated with resistance to adenine arabinoside in Toxoplasma gondii, and cloning of the adenosine kinase locus WJ Sullivan Jr, CW Chiang, CM Wilson, FNM Naguib, MH El Kouni, ... Molecular and biochemical parasitology 103 (1), 1-14, 1999 | 54 | 1999 |
Gypenosides induce apoptosis in human hepatoma Huh-7 cells through a calcium/reactive oxygen species-dependent mitochondrial pathway QF Wang, CW Chiang, CC Wu, CC Cheng, SJ Hsieh, JC Chen, YC Hsieh, ... Planta medica 73 (06), 535-544, 2007 | 51 | 2007 |
Proteolysis of integrin α5 and β1 subunits involved in retinoic acid-induced apoptosis in human hepatoma Hep3B cells SL Hsu, CC Cheng, YR Shi, CW Chiang Cancer letters 167 (2), 193-204, 2001 | 47 | 2001 |
NlpI facilitates deposition of C4bp on Escherichia coli by blocking classical complement-mediated killing, which results in high-level bacteremia Y Tseng, SW Wang, KS Kim, YH Wang, Y Yao, CC Chen, CW Chiang, ... Infection and immunity 80 (10), 3669-3678, 2012 | 34 | 2012 |
Nucleophosmin in the pathogenesis of arsenic-related bladder carcinogenesis revealed by quantitative proteomics SH Chen, YW Wang, JL Hsu, HY Chang, CY Wang, PT Shen, CW Chiang, ... Toxicology and applied pharmacology 242 (2), 126-135, 2010 | 29 | 2010 |
Identifying LRRC16B as an oncofetal gene with transforming enhancing capability using a combined bioinformatics and experimental approach CC Hsu, CW Chiang, HC Cheng, WT Chang, CY Chou, HW Tsai, CT Lee, ... Oncogene 30 (6), 654-667, 2011 | 20 | 2011 |
Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation CH Wang, PW Hung, CW Chiang, M Lombès, CH Chen, KH Lee, YC Lo, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (8), 1282-1297, 2019 | 18 | 2019 |
Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5 CW Chiang, WK Liu, CW Chiang, CK Chou Biochemical Journal 433 (1), 187-196, 2011 | 18 | 2011 |
Regulation of septin phosphorylation: SEPT12 phosphorylation in sperm septin assembly CH Lin, YR Shen, HY Wang, CW Chiang, CY Wang, PL Kuo Cytoskeleton 76 (1), 137-142, 2019 | 17 | 2019 |
Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells ST Mo, SJ Chiang, TY Lai, YL Cheng, CE Chung, SCH Kuo, KM Reece, ... PloS one 9 (12), e116074, 2014 | 17 | 2014 |