| Direct observation of individual endogenous protein complexes in situ by proximity ligation O Söderberg, M Gullberg, M Jarvius, K Ridderstråle, KJ Leuchowius, ... Nature methods 3 (12), 995-1000, 2006 | 2687 | 2006 |
| Protein detection using proximity-dependent DNA ligation assays S Fredriksson, M Gullberg, J Jarvius, C Olsson, K Pietras, ... Nature biotechnology 20 (5), 473-477, 2002 | 1740 | 2002 |
| A ligase-mediated gene detection technique U Landegren, R Kaiser, J Sanders, L Hood Science 241 (4869), 1077-1080, 1988 | 1620 | 1988 |
| Padlock probes: circularizing oligonucleotides for localized DNA detection M Nilsson, H Malmgren, M Samiotaki, M Kwiatkowski, BP Chowdhary, ... Science 265 (5181), 2085-2088, 1994 | 1112 | 1994 |
| Method of detecting a nucleotide change in nucleic acids U Landegren, L Hood US Patent 4,988,617, 1991 | 828 | 1991 |
| Multiplexed genotyping with sequence-tagged molecular inversion probes P Hardenbol, J Banér, M Jain, M Nilsson, EA Namsaraev, ... Nature biotechnology 21 (6), 673-678, 2003 | 805 | 2003 |
| Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall P Lindblom, H Gerhardt, S Liebner, A Abramsson, M Enge, M Hellström, ... Genes & development 17 (15), 1835-1840, 2003 | 783 | 2003 |
| Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens U Landegren Journal of immunological methods 67 (2), 379-388, 1984 | 782 | 1984 |
| Signal amplification of padlock probes by rolling circle replication J Baner, M Nilsson, M Mendel-Hartvig, U Landegren Nucleic acids research 26 (22), 5073-5078, 1998 | 720 | 1998 |
| Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay O Söderberg, KJ Leuchowius, M Gullberg, M Jarvius, I Weibrecht, ... Methods 45 (3), 227-232, 2008 | 645 | 2008 |
| Reading bits of genetic information: methods for single-nucleotide polymorphism analysis U Landegren, M Nilsson, PY Kwok Genome research 8 (8), 769-776, 1998 | 584 | 1998 |
| Cytokine detection by antibody-based proximity ligation M Gullberg, SM Gústafsdóttir, E Schallmeiner, J Jarvius, M Bjarnegård, ... Proceedings of the National Academy of Sciences 101 (22), 8420-8424, 2004 | 556 | 2004 |
| Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay. DA Nickerson, R Kaiser, S Lappin, J Stewart, L Hood, U Landegren Proceedings of the National Academy of Sciences 87 (22), 8923-8927, 1990 | 523 | 1990 |
| DNA diagnostics—molecular techniques and automation U Landegren, R Kaiser, CT Caskey, L Hood Science 242 (4876), 229-237, 1988 | 492 | 1988 |
| In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes C Larsson, J Koch, A Nygren, G Janssen, AK Raap, U Landegren, ... Nature methods 1 (3), 227-232, 2004 | 408 | 2004 |
| Circularizing nucleic acid probe able to interlock with a target sequence through catenation U Landegren, M Kwiatkowski US Patent 5,871,921, 1999 | 356 | 1999 |
| A deletion in the amelogenin gene (AMG) causes X-linked amelogenesis imperfecta (AIH1) M Lagerström, N Dahl, Y Nakahori, Y Nakagome, B Bäckman, ... Genomics 10 (4), 971-975, 1991 | 320 | 1991 |
| Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors M Schütte, T Risch, N Abdavi-Azar, K Boehnke, D Schumacher, M Keil, ... Nature communications 8 (1), 14262, 2017 | 319 | 2017 |
| In situ detection of phosphorylated platelet-derived growth factor receptor β using a generalized proximity ligation method M Jarvius, J Paulsson, I Weibrecht, KJ Leuchowius, AC Andersson, ... Molecular & cellular proteomics 6 (9), 1500-1509, 2007 | 309 | 2007 |
| Phosphorylation of inositol 1, 4, 5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis T Szado, V Vanderheyden, JB Parys, H De Smedt, K Rietdorf, ... Proceedings of the National Academy of Sciences 105 (7), 2427-2432, 2008 | 295 | 2008 |