追蹤
Reuben Shaw
Reuben Shaw
在 salk.edu 的電子郵件地址已通過驗證 - 首頁
標題
引用次數
引用次數
年份
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13637*2021
Resveratrol improves health and survival of mice on a high-calorie diet
JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ...
Nature 444 (7117), 337-342, 2006
54442006
AMPK phosphorylation of raptor mediates a metabolic checkpoint
DM Gwinn, DB Shackelford, DF Egan, MM Mihaylova, A Mery, ...
Molecular cell 30 (2), 214-226, 2008
44782008
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
MM Mihaylova, RJ Shaw
Nature cell biology 13 (9), 1016-1023, 2011
31812011
AMPK: guardian of metabolism and mitochondrial homeostasis
S Herzig, RJ Shaw
Nature reviews Molecular cell biology 19 (2), 121-135, 2018
31662018
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
DF Egan, DB Shackelford, MM Mihaylova, S Gelino, RA Kohnz, W Mair, ...
Science 331 (6016), 456-461, 2011
27732011
Ras, PI (3) K and mTOR signalling controls tumour cell growth
RJ Shaw, LC Cantley
Nature 441 (7092), 424-430, 2006
26622006
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ...
Science 310 (5754), 1642-1646, 2005
24042005
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ...
Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004
21702004
The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
DB Shackelford, RJ Shaw
Nature Reviews Cancer 9 (8), 563-575, 2009
21532009
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
YU Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang, O Park, Z Luo, ...
Cell metabolism 13 (4), 376-388, 2011
18242011
AMPK: mechanisms of cellular energy sensing and restoration of metabolic balance
D Garcia, RJ Shaw
Molecular cell 66 (6), 789-800, 2017
17162017
AMPK and PPARδ agonists are exercise mimetics
VA Narkar, M Downes, TY Ruth, E Embler, YX Wang, E Banayo, ...
Cell 134 (3), 405-415, 2008
15002008
The LKB1 tumor suppressor negatively regulates mTOR signaling
RJ Shaw, N Bardeesy, BD Manning, L Lopez, M Kosmatka, RA DePinho, ...
Cancer cell 6 (1), 91-99, 2004
12852004
AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
EQ Toyama, S Herzig, J Courchet, TL Lewis Jr, OC Losón, K Hellberg, ...
Science 351 (6270), 275-281, 2016
10572016
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
KA Lamia, UM Sachdeva, L DiTacchio, EC Williams, JG Alvarez, DF Egan, ...
Science 326 (5951), 437-440, 2009
10512009
LKB1 and AMP‐activated protein kinase control of mTOR signalling and growth
RJ Shaw
Acta physiologica 196 (1), 65-80, 2009
7892009
Glucose metabolism and cancer
RJ Shaw
Current opinion in cell biology 18 (6), 598-608, 2006
7152006
Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates
DF Egan, MGH Chun, M Vamos, H Zou, J Rong, CJ Miller, HJ Lou, ...
Molecular cell 59 (2), 285-297, 2015
7112015
The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
D Egan, J Kim, RJ Shaw, KL Guan
Autophagy 7 (6), 643-644, 2011
6762011
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