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| Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate A Salmeen, JN Andersen, MP Myers, TC Meng, JA Hinks, NK Tonks, ... Nature 423 (6941), 769-773, 2003 | 1155 | 2003 |
| The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR‐mediated protein–protein interactions AK Das, PTW Cohen, D Barford The EMBO journal, 1998 | 1078 | 1998 |
| Crystal structure of human protein tyrosine phosphatase 1B D Barford, AJ Flint, NK Tonks Science 263 (5152), 1397-1404, 1994 | 1023 | 1994 |
| Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases AJ Flint, T Tiganis, D Barford, NK Tonks Proceedings of the National Academy of Sciences 94 (5), 1680-1685, 1997 | 1004 | 1997 |
| The structure and mechanism of protein phosphatases: insights into catalysis and regulation D Barford, AK Das, MP Egloff Annual review of biophysics and biomolecular structure 27 (1), 133-164, 1998 | 997 | 1998 |
| Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1 MP Egloff, DF Johnson, G Moorhead, PTW Cohen, P Cohen, D Barford The EMBO journal, 1997 | 787 | 1997 |
| Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B Z Jia, D Barford, AJ Flint, NK Tonks Science 268 (5218), 1754-1758, 1995 | 783 | 1995 |
| Structural insights into mRNA recognition from a PIWI domain–siRNA guide complex JS Parker, SM Roe, D Barford Nature 434 (7033), 663-666, 2005 | 714 | 2005 |
| A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2 S George, JJ Rochford, C Wolfrum, SL Gray, S Schinner, JC Wilson, ... Science 304 (5675), 1325-1328, 2004 | 711 | 2004 |
| Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains D Komander, F Reyes‐Turcu, JDF Licchesi, P Odenwaelder, ... EMBO reports 10 (5), 466-473, 2009 | 705 | 2009 |
| Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP J Yang, P Cron, VM Good, V Thompson, BA Hemmings, D Barford Nature structural biology 9 (12), 940-944, 2002 | 645 | 2002 |
| TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B MP Myers, JN Andersen, A Cheng, ML Tremblay, CM Horvath, ... Journal of Biological Chemistry 276 (51), 47771-47774, 2001 | 637 | 2001 |
| The crystal structure of human eukaryotic release factor eRF1—mechanism of stop codon recognition and peptidyl-tRNA hydrolysis H Song, P Mugnier, AK Das, HM Webb, DR Evans, MF Tuite, ... Cell 100 (3), 311-321, 2000 | 620 | 2000 |
| The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs MR Groves, N Hanlon, P Turowski, BA Hemmings, D Barford Cell 96 (1), 99-110, 1999 | 612 | 1999 |
| Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate MP Egloff, PTW Cohen, P Reinemer, D Barford Journal of molecular biology 254 (5), 942-959, 1995 | 590 | 1995 |
| Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution. AK Das, NR Helps, PT Cohen, D Barford The EMBO journal 15 (24), 6798-6809, 1996 | 568 | 1996 |
| Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation J Yang, P Cron, V Thompson, VM Good, D Hess, BA Hemmings, ... Molecular cell 9 (6), 1227-1240, 2002 | 562 | 2002 |
| Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B A Salmeen, JN Andersen, MP Myers, NK Tonks, D Barford Molecular cell 6 (6), 1401-1412, 2000 | 558 | 2000 |
| Molecular mechanisms of theprotein serine/threonine phosphatases D Barford Trends in biochemical sciences 21 (11), 407-412, 1996 | 554 | 1996 |