| RNAi-mediated gene silencing in non-human primates TS Zimmermann, ACH Lee, A Akinc, B Bramlage, D Bumcrot, MN Fedoruk, ... Nature 441 (7089), 111-114, 2006 | 1898 | 2006 |
| Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs DV Morrissey, JA Lockridge, L Shaw, K Blanchard, K Jensen, W Breen, ... Nature biotechnology 23 (8), 1002-1007, 2005 | 1560 | 2005 |
| Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA AD Judge, V Sood, JR Shaw, D Fang, K McClintock, I MacLachlan Nature biotechnology 23 (4), 457-462, 2005 | 1559 | 2005 |
| Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo AD Judge, G Bola, ACH Lee, I MacLachlan Molecular Therapy 13 (3), 494-505, 2006 | 768 | 2006 |
| Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study TW Geisbert, ACH Lee, M Robbins, JB Geisbert, AN Honko, V Sood, ... The Lancet 375 (9729), 1896-1905, 2010 | 600 | 2010 |
| siRNA and innate immunity M Robbins, A Judge, I MacLachlan Oligonucleotides 19 (2), 89-102, 2009 | 539 | 2009 |
| Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice AD Judge, M Robbins, I Tavakoli, J Levi, L Hu, A Fronda, E Ambegia, ... The Journal of clinical investigation 119 (3), 661-673, 2009 | 464 | 2009 |
| Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells AD Judge, X Zhang, H Fujii, CD Surh, J Sprent The Journal of experimental medicine 196 (7), 935-946, 2002 | 456 | 2002 |
| 2′-O-methyl-modified RNAs act as TLR7 antagonists M Robbins, A Judge, L Liang, K McClintock, E Yaworski, I MacLachlan Molecular Therapy 15 (9), 1663-1669, 2007 | 425 | 2007 |
| The changing preference of T and B cells for partners as T‐dependent antibody responses develop ICM MacLennan, A Gulbranson‐Judge, KM Toellner, ... Immunological reviews 156 (1), 53-66, 1997 | 373 | 1997 |
| Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5–positive CD4 cells and germinal centers LSK Walker, A Gulbranson-Judge, S Flynn, T Brocker, C Raykundalia, ... The Journal of experimental medicine 190 (8), 1115-1122, 1999 | 360 | 1999 |
| Overcoming the innate immune response to small interfering RNA A Judge, I Maclachlan Human gene therapy 19 (2), 111-124, 2008 | 341 | 2008 |
| Modified siRNA molecules and uses thereof I Maclachlan, A Judge US Patent 8,101,741, 2012 | 336 | 2012 |
| Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference TW Geisbert, LE Hensley, E Kagan, EZ Yu, JB Geisbert, ... Journal of Infectious Diseases 193 (12), 1650-1657, 2006 | 332 | 2006 |
| Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes A Judge, K McClintock, JR Phelps, I MacLachlan Molecular Therapy 13 (2), 328-337, 2006 | 327 | 2006 |
| Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation M Robbins, A Judge, E Ambegia, C Choi, E Yaworski, L Palmer, ... Human gene therapy 19 (10), 991-999, 2008 | 322 | 2008 |
| Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation. KM Toellner, A Gulbranson-Judge, DR Taylor, DM Sze, IC MacLennan The Journal of experimental medicine 183 (5), 2303-2312, 1996 | 277 | 1996 |
| CD4+ CD3− accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells MY Kim, FMC Gaspal, HE Wiggett, FM McConnell, A Gulbranson-Judge, ... Immunity 18 (5), 643-654, 2003 | 275 | 2003 |
| CD4 T cell traffic control: in vivo evidence that ligation of OX40 on CD4 T cells by OX40‐ligand expressed on dendritic cells leads to the accumulation of CD4 T … T Brocker, A Gulbranson‐Judge, S Flynn, M Riedinger, C Raykundalia, ... European journal of immunology 29 (5), 1610-1616, 1999 | 255 | 1999 |
| Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool M Turner, A Gulbranson-Judge, ME Quinn, AE Walters, ICM MacLennan, ... The Journal of experimental medicine 186 (12), 2013-2021, 1997 | 212 | 1997 |
