Sequence specificity in the dimerization of transmembrane. alpha.-helixes MA Lemmon, JM Flanagan, HR Treutlein, J Zhang, DM Engelman Biochemistry 31 (51), 12719-12725, 1992 | 663 | 1992 |
A dimerization motif for transmembrane α–helices MA Lemmon, HR Treutlein, PD Adams, AT Brünger, DM Engelman Nature structural biology 1 (3), 157-163, 1994 | 419 | 1994 |
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor IS Lucet, E Fantino, M Styles, R Bamert, O Patel, SE Broughton, M Walter, ... Blood 107 (1), 176-183, 2006 | 331 | 2006 |
The glycophorin A transmembrane domain dimer: Sequence-specific propensity for a right-handed supercoil of helixes HR Treutlein, MA Lemmon, DM Engelman, A Brunger Biochemistry 31 (51), 12726-12732, 1992 | 214 | 1992 |
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells JR Stehn, NK Haass, T Bonello, M Desouza, G Kottyan, H Treutlein, ... Cancer research 73 (16), 5169-5182, 2013 | 204 | 2013 |
Chromophore-protein interactions and the function of the photosynthetic reaction center: a molecular dynamics study. H Treutlein, K Schulten, AT Brünger, M Karplus, J Deisenhofer, H Michel Proceedings of the National Academy of Sciences 89 (1), 75-79, 1992 | 151 | 1992 |
Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen FM Smith, C Vearing, M Lackmann, H Treutlein, J Himanen, K Chen, ... Journal of Biological Chemistry 279 (10), 9522-9531, 2004 | 131 | 2004 |
Structure‐function analysis of human IL‐6: identification of two distinct regions that are important for receptor binding A Hammacher, LD Ward, RJ Simpson, J Weinstock, H Treutlein, ... Protein Science 3 (12), 2280-2293, 1994 | 125 | 1994 |
Electric field effects on insulin chain-B conformation A Budi, FS Legge, H Treutlein, I Yarovsky The Journal of Physical Chemistry B 109 (47), 22641-22648, 2005 | 124 | 2005 |
Noise Induced Limit Cycles of the Bonhoeffer‐Van der Pol Model of Neural Pulses H Treutlein, K Schulten Berichte der Bunsengesellschaft für physikalische Chemie 89 (6), 710-718, 1985 | 93 | 1985 |
Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs) CJ Burns, DG Bourke, L Andrau, X Bu, SA Charman, AC Donohue, ... Bioorganic & medicinal chemistry letters 19 (20), 5887-5892, 2009 | 88 | 2009 |
Effect of frequency on insulin response to electric field stress A Budi, FS Legge, H Treutlein, I Yarovsky The Journal of Physical Chemistry B 111 (20), 5748-5756, 2007 | 85 | 2007 |
Systematic comparison of empirical forcefields for molecular dynamic simulation of insulin N Todorova, FS Legge, H Treutlein, I Yarovsky The Journal of Physical Chemistry B 112 (35), 11137-11146, 2008 | 78 | 2008 |
Selective Kinase Inhibitors ML Styles, J Zeng, HR Treutlein, AF Wilks, MR Kling, CJ Burns, X Bu US Patent App. 10/585,916, 2008 | 73 | 2008 |
Identification of ligand-binding site III on the immunoglobulin-like domain of the granulocyte colony-stimulating factor receptor JE Layton, NE Hall, F Connell, J Venhorst, HR Treutlein Journal of Biological Chemistry 276 (39), 36779-36787, 2001 | 69 | 2001 |
Protein flexibility: Multiple molecular dynamics simulations of insulin chain B FS Legge, A Budi, H Treutlein, I Yarovsky Biophysical chemistry 119 (2), 146-157, 2006 | 67 | 2006 |
Interaction of granulocyte colony-stimulating factor (G-CSF) with its receptor: evidence that Glu19 of G-CSF interacts with Arg288 of the receptor JE Layton, G Shimamoto, T Osslund, A Hammacher, DK Smith, ... Journal of Biological Chemistry 274 (25), 17445-17451, 1999 | 63 | 1999 |
Effects of Thioamide Substitutions on the Conformation and Stability of α- and 310-Helices Tran, J Zeng, H Treutlein, AW Burgess Journal of the American Chemical Society 124 (18), 5222-5230, 2002 | 61 | 2002 |
Identification of cancer-targeted tropomyosin inhibitors and their synergy with microtubule drugs MA Currier, JR Stehn, A Swain, D Chen, J Hook, E Eiffe, A Heaton, ... Molecular cancer therapeutics 16 (8), 1555-1565, 2017 | 55 | 2017 |
Effect of external stresses on protein conformation: a computer modelling study A Budi, S Legge, H Treutlein, I Yarovsky European Biophysics Journal 33, 121-129, 2004 | 55 | 2004 |