Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells. P Westermark, C Wernstedt, E Wilander, DW Hayden, TD O'Brien, ... Proceedings of the National Academy of Sciences 84 (11), 3881-3885, 1987 | 1202 | 1987 |
Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells RM Dwyer, SM Potter-Beirne, KA Harrington, AJ Lowery, E Hennessy, ... Clinical Cancer Research 13 (17), 5020-5027, 2007 | 540 | 2007 |
Feline renal failure: questions, answers, questions. JP Lulich, TD O'Brien, CA Osborne, DJ Polzin | 403 | 1992 |
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT) FT Martin, RM Dwyer, J Kelly, S Khan, JM Murphy, C Curran, N Miller, ... Breast cancer research and treatment 124, 317-326, 2010 | 369 | 2010 |
Islet amyloid in type 2 human diabetes mellitus and adult diabetic cats contains a novel putative polypeptide hormone. P Westermark, C Wernstedt, TD O'Brien, DW Hayden, KH Johnson The American journal of pathology 127 (3), 414, 1987 | 361 | 1987 |
Immunogenicity of allogeneic mesenchymal stem cells S Schu, M Nosov, L O'Flynn, G Shaw, O Treacy, F Barry, M Murphy, ... Journal of cellular and molecular medicine 16 (9), 2094-2103, 2012 | 354 | 2012 |
Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat GF Curley, M Hayes, B Ansari, G Shaw, A Ryan, F Barry, T O'Brien, ... Thorax 67 (6), 496-501, 2012 | 338 | 2012 |
Hyperlipidemia in patients with primary and secondary hypothyroidism T O'brien, SF DINNEEN, PC O'BRIEN, PJ PALUMBO Mayo Clinic Proceedings 68 (9), 860-866, 1993 | 323 | 1993 |
Effects of immunosuppressants on receptor activator of NF-κB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells LC Hofbauer, C Shui, BL Riggs, CR Dunstan, TC Spelsberg, T O'Brien, ... Biochemical and biophysical research communications 280 (1), 334-339, 2001 | 311 | 2001 |
Islet amyloid, islet-amyloid polypeptide, and diabetes mellitus KH Johnson, TD O'Brien, C Betsholtz, P Westermark New England Journal of Medicine 321 (8), 513-518, 1989 | 308 | 1989 |
Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds NN Madigan, S McMahon, T O’Brien, MJ Yaszemski, AJ Windebank Respiratory physiology & neurobiology 169 (2), 183-199, 2009 | 266 | 2009 |
ER stress contributes to ischemia-induced cardiomyocyte apoptosis E Szegezdi, A Duffy, ME O’Mahoney, SE Logue, LA Mylotte, T O’Brien, ... Biochemical and biophysical research communications 349 (4), 1406-1411, 2006 | 266 | 2006 |
Differential miRNA expression in omental adipose tissue and in the circulation of obese patients identifies novel metabolic biomarkers HM Heneghan, N Miller, OJ McAnena, T O'brien, MJ Kerin The Journal of Clinical Endocrinology & Metabolism 96 (5), E846-E850, 2011 | 265 | 2011 |
Immunolocalization of islet amyloid polypeptide (IAPP) in pancreatic beta cells by means of peroxidase-antiperoxidase (PAP) and protein A-gold techniques. KH Johnson, TD O'brien, DW Hayden, K Jordan, HK Ghobrial, ... The American journal of pathology 130 (1), 1, 1988 | 262 | 1988 |
Evidence for proteotoxicity in β cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway T Gurlo, S Ryazantsev, C Huang, MW Yeh, HA Reber, OJ Hines, ... The American journal of pathology 176 (2), 861-869, 2010 | 261 | 2010 |
Hyperlipidemia and diabetes mellitus T O'Brien, TT Nguyen, BR Zimmerman Mayo Clinic Proceedings 73 (10), 969-976, 1998 | 250 | 1998 |
Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat J Devaney, S Horie, C Masterson, S Elliman, F Barry, T O'Brien, GF Curley, ... Thorax 70 (7), 625-635, 2015 | 242 | 2015 |
Gene transfer into rat mesenchymal stem cells: a comparative study of viral and nonviral vectors JM McMahon, S Conroy, M Lyons, U Greiser, C O'shea, P Strappe, ... Stem cells and development 15 (1), 87-96, 2006 | 240 | 2006 |
Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment LA Mylotte, AM Duffy, M Murphy, T O'Brien, A Samali, F Barry, E Szegezdi Stem cells 26 (5), 1325-1336, 2008 | 237 | 2008 |
Prospective evaluation of Roux-en-Y gastric bypass as primary operation for medically complicated obesity BM Balsiger, FP Kennedy, HS Abu-Lebdeh, M Collazo-Clavell, ... Mayo Clinic Proceedings 75 (7), 673-680, 2000 | 222 | 2000 |