| Conserved folding in retroviral proteases: crystal structure of synthetic HIV-1 protease A Wlodawer, M Miller, M Jaskólski, BK Sathyanarayana, E Baldwin, ... Science 245 (4918), 616-621, 1989 | 1549 | 1989 |
| The structure of the E. coli recA protein monomer and polymer RM Story, IT Weber, TA Steitz Nature 355 (6358), 318-325, 1992 | 991 | 1992 |
| Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 Å resolution IT Weber, TA Steitz Journal of molecular biology 198 (2), 311-326, 1987 | 589 | 1987 |
| Crystal structure of interleukin 8: symbiosis of NMR and crystallography. ET Baldwin, IT Weber, R St Charles, JC Xuan, E Appella, M Yamada, ... Proceedings of the National Academy of Sciences 88 (2), 502-506, 1991 | 523 | 1991 |
| Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human … Y Koh, H Nakata, K Maeda, H Ogata, G Bilcer, T Devasamudram, ... Antimicrobial agents and chemotherapy 47 (10), 3123-3129, 2003 | 471 | 2003 |
| Model structure of decorin and implications for collagen fibrillogenesis IT Weber, RW Harrison, RV Iozzo Journal of Biological Chemistry 271 (50), 31767-31770, 1996 | 453 | 1996 |
| Structure and function of epidermal growth factor‐like regions in proteins E Appella, IT Weber, F Blasi FEBS letters 231 (1), 1-4, 1988 | 406 | 1988 |
| Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families G Velho, H Blanche, M Vaxillaire, C Bellanne-Chantelot, VC Pardini, ... Diabetologia 40, 217-224, 1997 | 398 | 1997 |
| Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus. M Stoffel, PH Froguel, J Takeda, H Zouali, N Vionnet, S Nishi, IT Weber, ... Proceedings of the National Academy of Sciences 89 (16), 7698-7702, 1992 | 306 | 1992 |
| Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP. DB McKay, IT Weber, TA Steitz Journal of Biological Chemistry 257 (16), 9518-9524, 1982 | 299 | 1982 |
| Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance AK Ghosh, BD Chapsal, IT Weber, H Mitsuya Accounts of chemical research 41 (1), 78-86, 2008 | 296 | 2008 |
| High resolution crystal structures of HIV-1 protease with a potent non-peptide inhibitor (UIC-94017) active against multi-drug-resistant clinical strains Y Tie, PI Boross, YF Wang, L Gaddis, AK Hussain, S Leshchenko, ... Journal of molecular biology 338 (2), 341-352, 2004 | 282 | 2004 |
| Molecular modeling of the HIV-1 protease and its substrate binding site IT Weber, M Miller, M Jaskólski, J Leis, AM Skalka, A Wlodawer Science 243 (4893), 928-931, 1989 | 243 | 1989 |
| Glucokinase mutations, insulin secretion, and diabetes mellitus. GI Bell, SJ Pilkis, IT Weber, KS Polonsky Annual Review of Physiology 58, 171-186, 1996 | 208 | 1996 |
| Geometric criteria of hydrogen bonds in proteins and identification ofbifurcated'hydrogen bonds IY Torshin, IT Weber, RW Harrison Protein engineering 15 (5), 359-363, 2002 | 196 | 2002 |
| Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity. IT Weber, TA Steitz Proceedings of the National Academy of Sciences 81 (13), 3973-3977, 1984 | 193 | 1984 |
| Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase IT Weber, TA Steitz, J Bubis, SS Taylor Biochemistry 26 (2), 343-351, 1987 | 190 | 1987 |
| The cAMP-binding domains of the regulatory subunit of cAMP-dependent protein kinase and the catabolite gene activator protein are homologous. IT Weber, K Takio, K Titani, TA Steitz Proceedings of the National Academy of Sciences 79 (24), 7679-7683, 1982 | 185 | 1982 |
| Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance AK Ghosh, PR Sridhar, S Leshchenko, AK Hussain, J Li, AY Kovalevsky, ... Journal of Medicinal Chemistry 49 (17), 5252-5261, 2006 | 177 | 2006 |
| HIV-1 protease: structural perspectives on drug resistance IT Weber, J Agniswamy Viruses 1 (3), 1110, 2009 | 175 | 2009 |
Robert HarrisonProfessor of computer science, georgia state university在 cs.gsu.edu 的电子邮件经过验证