Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10285), 1637, 2021 | 2493* | 2021 |
A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex LP Jackson, BT Kelly, AJ McCoy, T Gaffry, LC James, BM Collins, ... Cell 141 (7), 1220-1229, 2010 | 393 | 2010 |
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The Lancet 400 (10349), 359-368, 2022 | 269 | 2022 |
Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 399 (10320), 143, 2022 | 256 | 2022 |
Multivariate proteomic profiling identifies novel accessory proteins of coated vesicles GHH Borner, R Antrobus, J Hirst, GS Bhumbra, P Kozik, LP Jackson, ... Journal of Cell Biology 197 (1), 141-160, 2012 | 180 | 2012 |
Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb PR Pryor, L Jackson, SR Gray, MA Edeling, A Thompson, CM Sanderson, ... Cell 134 (5), 817-827, 2008 | 165 | 2008 |
Molecular basis for recognition of dilysine trafficking motifs by COPI LP Jackson, M Lewis, HM Kent, MA Edeling, PR Evans, R Duden, ... Developmental cell 23 (6), 1255-1262, 2012 | 156 | 2012 |
AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A AK Davies, DN Itzhak, JR Edgar, TL Archuleta, J Hirst, LP Jackson, ... Nature communications 9 (1), 3958, 2018 | 136 | 2018 |
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface GG Hesketh, I Pérez-Dorado, LP Jackson, L Wartosch, IB Schäfer, ... Developmental cell 29 (5), 591-606, 2014 | 128 | 2014 |
Structure and mechanism of COPI vesicle biogenesis LP Jackson Current opinion in cell biology 29, 67-73, 2014 | 125 | 2014 |
Surface Features of Potato Virus X from Fiber Diffraction L Parker, K Amy, G Stubbs Virology 300 (2), 291-5, 2002 | 86 | 2002 |
COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal P Xu, HM Hankins, C MacDonald, SJ Erlinger, MN Frazier, NS Diab, ... elife 6, e28342, 2017 | 72 | 2017 |
Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open … RECOVERY Collaborative Group Lancet (London, England) 401 (10387), 1499, 2023 | 70 | 2023 |
What is the optimal duration of human chorionic gonadotrophin surveillance following evacuation of a molar pregnancy? A retrospective analysis on over 20,000 consecutive patients C Coyle, D Short, L Jackson, NJ Sebire, B Kaur, R Harvey, PM Savage, ... Gynecologic oncology 148 (2), 254-257, 2018 | 57 | 2018 |
Toward understanding the molecular role of SNX27/retromer in human health and disease M Chandra, AK Kendall, LP Jackson Frontiers in Cell and Developmental Biology 9, 642378, 2021 | 42 | 2021 |
Mammalian retromer is an adaptable scaffold for cargo sorting from endosomes AK Kendall, B Xie, P Xu, J Wang, R Burcham, MN Frazier, E Binshtein, ... Structure 28 (4), 393-405. e4, 2020 | 40 | 2020 |
Molecular basis for the interaction between AP4 β4 and its accessory protein, tepsin MN Frazier, AK Davies, M Voehler, AK Kendall, GHH Borner, WJ Chazin, ... Traffic 17 (4), 400-415, 2016 | 30 | 2016 |
Structures and mechanisms of vesicle coat components and multisubunit tethering complexes LP Jackson, D Kümmel, KM Reinisch, DJ Owen Current opinion in cell biology 24 (4), 475-483, 2012 | 30 | 2012 |
Association between SGLT2 inhibitor treatment and diabetic ketoacidosis and mortality in people with type 2 diabetes admitted to hospital with COVID-19 K Khunti, Y Ruan, J Davies, BCT Field, S Harris, M Kosiborod, D Nagi, ... Diabetes Care 45 (12), 2838-2843, 2022 | 20 | 2022 |
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex KE Chen, Q Guo, TA Hill, Y Cui, AK Kendall, Z Yang, RJ Hall, MD Healy, ... Science Advances 7 (49), eabg4007, 2021 | 20 | 2021 |