| The concise guide to pharmacology 2019/20: Enzymes SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ... British Journal of Pharmacology 176, S297-S396, 2019 | 539 | 2019 |
| The concise guide to pharmacology 2021/22: Enzymes SPH Alexander, D Fabbro, E Kelly, A Mathie, JA Peters, EL Veale, ... British journal of pharmacology 178, S313-S411, 2021 | 379 | 2021 |
| The activation of the biguanide antimalarial proguanil co‐segregates with the mephenytoin oxidation polymorphism‐a panel study. SA Ward, NA Helsby, E Skjelbo, K Brosen, LF Gram, AM Breckenridge British journal of clinical pharmacology 31 (6), 689-692, 1991 | 186 | 1991 |
| The concise guide to PHARMACOLOGY 2023/24: enzymes SPH Alexander, D Fabbro, E Kelly, AA Mathie, JA Peters, EL Veale, ... British Journal of Pharmacology 180, S289-S373, 2023 | 160 | 2023 |
| The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution G Edwards, A Dingsdale, N Helsby, MLE Orme, AM Breckenridge European journal of clinical pharmacology 35, 681-684, 1988 | 113 | 1988 |
| 2-Amino metabolites are key mediators of CB 1954 and SN 23862 bystander effects in nitroreductase GDEPT NA Helsby, DM Ferry, AV Patterson, SM Pullen, WR Wilson British journal of cancer 90 (5), 1084-1092, 2004 | 110 | 2004 |
| Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures WR Wilson, SM Pullen, A Hogg, NA Helsby, KO Hicks, WA Denny Cancer Research 62 (5), 1425-1432, 2002 | 102 | 2002 |
| The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism. NA Helsby, SA Ward, G Edwards, RE Howells, AM Breckenridge British journal of clinical pharmacology 30 (4), 593-598, 1990 | 93 | 1990 |
| Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn’s disease HM Lin, MPG Barnett, NC Roy, NI Joyce, S Zhu, K Armstrong, NA Helsby, ... Journal of proteome research 9 (4), 1965-1975, 2010 | 90 | 2010 |
| Nontargeted urinary metabolite profiling of a mouse model of Crohn’s disease HM Lin, SJ Edmunds, NA Helsby, LR Ferguson, DD Rowan Journal of proteome research 8 (4), 2045-2057, 2009 | 84 | 2009 |
| Effect of nitroreduction on the alkylating reactivity and cytotoxicity of the 2, 4-dinitrobenzamide-5-aziridine CB 1954 and the corresponding nitrogen mustard SN 23862 … NA Helsby, SJ Wheeler, FB Pruijn, BD Palmer, S Yang, WA Denny, ... Chemical research in toxicology 16 (4), 469-478, 2003 | 84 | 2003 |
| Using metabolomic analysis to understand inflammatory bowel diseases HM Lin, NA Helsby, DD Rowan, LR Ferguson Inflammatory bowel diseases 17 (4), 1021-1029, 2011 | 77 | 2011 |
| Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards WR Wilson, KO Hicks, SM Pullen, DM Ferry, NA Helsby, AV Patterson Radiation research 167 (6), 625-636, 2007 | 76 | 2007 |
| In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme. NA Helsby, SA Ward, RE Howells, AM Breckenridge British journal of clinical pharmacology 30 (2), 287-291, 1990 | 74 | 1990 |
| Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans J Lu, N Helsby, BD Palmer, M Tingle, BC Baguley, P Kestell, LM Ching Journal of Pharmacology and Experimental Therapeutics 310 (2), 571-577, 2004 | 71 | 2004 |
| Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes NA Helsby, S Zhu, AE Pearson, MD Tingle, LR Ferguson Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 454 (1 …, 2000 | 66 | 2000 |
| CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype NA Helsby, WY Lo, K Sharples, G Riley, M Murray, K Spells, M Dzhelai, ... British journal of cancer 99 (8), 1251-1255, 2008 | 64 | 2008 |
| The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation NA Helsby, CY Hui, MA Goldthorpe, JK Coller, MC Soh, PJ Gow, ... British journal of clinical pharmacology 70 (6), 844-853, 2010 | 63 | 2010 |
| Trypanocidal activity of aziridinyl nitrobenzamide prodrugs C Bot, BS Hall, N Bashir, MC Taylor, NA Helsby, SR Wilkinson Antimicrobial agents and chemotherapy 54 (10), 4246-4252, 2010 | 59 | 2010 |
| Inhibition of mouse and human CYP 1A-and 2E1-dependent substrate metabolism by the isoflavonoids genistein and equol NA Helsby, JK Chipman, A Gescher, D Kerr Food and chemical toxicology 36 (5), 375-382, 1998 | 59 | 1998 |
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