K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac YY Dong, ACW Pike, A Mackenzie, C McClenaghan, P Aryal, L Dong, ... Science 347 (6227), 1256-1259, 2015 | 333 | 2015 |
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing R O’Flaherty, A Bergin, E Flampouri, LM Mota, I Obaidi, A Quigley, Y Xie, ... Biotechnology advances 43, 107552, 2020 | 208 | 2020 |
The structural basis of ZMPSTE24-dependent laminopathies A Quigley, YY Dong, ACW Pike, L Dong, L Shrestha, G Berridge, ... Science 339 (6127), 1604-1607, 2013 | 127 | 2013 |
A lower X-gate in TASK channels traps inhibitors within the vestibule KEJ Rödström, AK Kiper, W Zhang, S Rinne, ACW Pike, M Goldstein, ... Nature 582 (7812), 443-447, 2020 | 77 | 2020 |
Mammalian glucose transporter activity is dependent upon anionic and conical phospholipids RC Hresko, TE Kraft, A Quigley, EP Carpenter, PW Hruz Journal of Biological Chemistry 291 (33), 17271-17282, 2016 | 74 | 2016 |
Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24 S Mehmood, J Marcoux, J Gault, A Quigley, S Michaelis, SG Young, ... Nature chemistry 8 (12), 1152-1158, 2016 | 72 | 2016 |
The structural basis of fatty acid elongation by the ELOVL elongases L Nie, TC Pascoa, ACW Pike, SR Bushell, A Quigley, GF Ruda, A Chu, ... Nature structural & molecular biology 28 (6), 512-520, 2021 | 65 | 2021 |
Reconstruction and Morphometric Analysis of the Nasal Airway of the White‐Tailed Deer (Odocoileus virginianus) and Implications Regarding Respiratory and … AN Ranslow, JP Richter, T Neuberger, B Van Valkenburgh, CR Rumple, ... The Anatomical Record 297 (11), 2138-2147, 2014 | 49 | 2014 |
Changes in membrane protein structural biology J Birch, H Cheruvara, N Gamage, PJ Harrison, R Lithgo, A Quigley Biology 9 (11), 401, 2020 | 36 | 2020 |
Chronic Infection by Mucoid Pseudomonas aeruginosa Associated with Dysregulation in T-Cell Immunity to Outer Membrane Porin F KJ Quigley, CJ Reynolds, A Goudet, EJ Raynsford, R Sergeant, A Quigley, ... American Journal of Respiratory and Critical Care Medicine 191 (11), 1250-1264, 2015 | 35 | 2015 |
The role of protein hydrolysates in prolonging viability and enhancing antibody production of CHO cells I Obaidi, LM Mota, A Quigley, M Butler Applied Microbiology and Biotechnology 105, 3115-3129, 2021 | 17 | 2021 |
A review of the approaches used to solve sub-100 kDa membrane proteins by cryo-electron microscopy PJ Harrison, T Vecerkova, DK Clare, A Quigley Journal of Structural Biology 215 (2), 107959, 2023 | 13 | 2023 |
Transient transfection and expression of eukaryotic membrane proteins in Expi293F cells and their screening on a small scale: application for structural studies GO Krasnoselska, M Dumoux, N Gamage, H Cheruvara, J Birch, ... Structural Proteomics: High-Throughput Methods, 105-128, 2021 | 12 | 2021 |
A new paradigm for Prelamin A proteolytic processing by ZMPSTE24: the upstream SY^ LL cleavage occurs first and there is no CaaX processing by ZMPSTE24 L Nie, E Spear, TD Babatz, A Quigley, YY Dong, A Chu, B Rotty, R Chalk, ... bioRxiv, 2020.05. 13.093849, 2020 | 8 | 2020 |
Structural Biology and Structure–Function Relationships of Membrane Proteins I Moraes, A Quigley Biology 10 (3), 245, 2021 | 6 | 2021 |
A unique lower X-gate in TASK channels traps inhibitors within the vestibule KEJ Rödström, AK Kiper, W Zhang, S Rinné, ACW Pike, M Goldstein, ... bioRxiv, 706168, 2019 | 4 | 2019 |
A comparative study of the anatomy and functional morphology of the mammalian nasal cavity AP Quigley | 4 | 2015 |
Structural basis of the mechanism and inhibition of a human ceramide synthase TC Pascoa, ACW Pike, CS Tautermann, G Chi, M Traub, A Quigley, ... Nature Structural & Molecular Biology, 1-10, 2024 | 3 | 2024 |
High-Throughput Production and Optimization of Membrane Proteins After Expression in Mammalian Cells N Gamage, H Cheruvara, PJ Harrison, J Birch, CJ Hitchman, M Olejnik, ... Advanced Methods in Structural Biology, 79-118, 2023 | 3 | 2023 |
The high-throughput production of membrane proteins J Birch, A Quigley Emerging Topics in Life Sciences 5 (5), 655-663, 2021 | 3 | 2021 |