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Hengrui Liu
Hengrui Liu
在 rockefeller.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
MM Gaschler, AA Andia, H Liu, JM Csuka, B Hurlocker, CA Vaiana, ...
Nature chemical biology 14 (5), 507-515, 2018
6322018
Imidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model
Y Zhang, H Tan, JD Daniels, F Zandkarimi, H Liu, LM Brown, K Uchida, ...
Cell chemical biology 26 (5), 623-633. e9, 2019
5632019
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors
S Iketani, F Forouhar, H Liu, SJ Hong, FY Lin, MS Nair, A Zask, Y Huang, ...
Nature communications 12 (1), 2016, 2021
1122021
Targeting dependency on the GPX4 lipid peroxide repair pathway for cancer therapy
H Liu, SL Schreiber, BR Stockwell
Biochemistry 57 (14), 2059-2060, 2018
832018
Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19
H Liu, S Iketani, A Zask, N Khanizeman, E Bednarova, F Forouhar, ...
Nature communications 13 (1), 1891, 2022
722022
Characterization of a patient-derived variant of GPX4 for precision therapy
H Liu, F Forouhar, T Seibt, R Saneto, K Wigby, J Friedman, X Xia, ...
Nature chemical biology 18 (1), 91-100, 2022
632022
Small-molecule allosteric inhibitors of GPX4
H Liu, F Forouhar, AJ Lin, Q Wang, V Polychronidou, RK Soni, X Xia, ...
Cell chemical biology 29 (12), 1680-1693. e9, 2022
452022
Inhibitors of coronavirus 3CL proteases protect cells from protease-mediated cytotoxicity
SJ Resnick, S Iketani, SJ Hong, A Zask, H Liu, S Kim, S Melore, FY Lin, ...
Journal of Virology 95 (14), 10.1128/jvi. 02374-20, 2021
332021
A simplified cell-based assay to identify coronavirus 3CL protease inhibitors
SJ Resnick, S Iketani, SJ Hong, A Zask, H Liu, S Kim, S Melore, MS Nair, ...
Biorxiv, 2020
82020
APR-246 increases tumor antigenicity independent of p53
J Michels, D Venkatesh, C Liu, S Budhu, H Zhong, MM George, D Thach, ...
Life Science Alliance 7 (1), 2024
2024
Gpx4 compounds and compositions and methods of treatment using same
BR Stockwell, H LIU, F FOROUHAR, Q Wang
US Patent US20230167058A1, 2023
2023
Gpx4 inhibitors and uses thereof
BR Stockwell, H LIU, F FOROUHAR, X XIA, A LIN, Q Wang
WO Patent WO2023039510A1, 2023
2023
Gpx4 compounds and compositions and methods of treatment using same
BR Stockwell, H LIU, F FOROUHAR, Q Wang
EP Patent EP4117642A1, 2023
2023
Probing Diseases using Small Molecules
H Liu
Columbia University, 2021
2021
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