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Ziga Jakopin
Ziga Jakopin
Professor of Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana
在 ffa.uni-lj.si 的电子邮件经过验证
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引用次数
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年份
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
A Noto, C De Vitis, ME Pisanu, G Roscilli, G Ricci, A Catizone, ...
Oncogene 36 (32), 4573-4584, 2017
1842017
Structural features of subtype-selective EP receptor modulators
T Markovič, Ž Jakopin, MS Dolenc, I Mlinarič-Raščan
Drug discovery today 22 (1), 57-71, 2017
1732017
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted …
A Šmelcerović, K Tomović, Ž Šmelcerović, Ž Petronijević, G Kocić, ...
European journal of medicinal chemistry 135, 491-516, 2017
1222017
Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells
ME Pisanu, A Noto, C De Vitis, S Morrone, G Scognamiglio, G Botti, ...
Cancer letters 406, 93-104, 2017
1202017
Recent Advances in the Synthesis of 1, 2, 4-and 1, 3, 4-Oxadiazoles
Z Jakopin, MS Dolenc
Current organic chemistry 12 (10), 850-898, 2008
982008
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
V Schijns, A Fernández‐Tejada, Ž Barjaktarović, I Bouzalas, J Brimnes, ...
Immunological reviews 296 (1), 169-190, 2020
782020
Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition
N Lobello, F Biamonte, ME Pisanu, MC Faniello, Ž Jakopin, E Chiarella, ...
Oncotarget 7 (38), 62019, 2016
782016
Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma
ME Pisanu, M Maugeri-Saccà, L Fattore, S Bruschini, C De Vitis, E Tabbì, ...
Journal of Experimental & Clinical Cancer Research 37, 1-17, 2018
752018
Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway
Z Jakopin
Journal of medicinal chemistry 57 (16), 6897-6918, 2014
752014
3,4-Dihydro-2H-1,4-benzoxazine Derivatives Combining Thrombin Inhibitory and Glycoprotein IIb/IIIa Receptor Antagonistic Activity as a Novel Class of …
J Ilaš, Z Jakopin, T Borštnar, M Stegnar, D Kikelj
Journal of medicinal chemistry 51 (18), 5617-5629, 2008
692008
Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors
Ž Jakopin, J Ilaš, M Barančoková, M Brvar, P Tammela, MS Dolenc, ...
European Journal of Medicinal Chemistry 130, 171-184, 2017
672017
Antioxidant and anti-inflammatory properties of 1, 2, 4-oxadiazole analogs of resveratrol
M Gobec, T Tomašič, T Markovič, I Mlinarič-Raščan, MS Dolenc, ...
Chemico-Biological Interactions 240, 200-207, 2015
632015
Advances in the chemistry of saccharins: From synthetic novelties towards biologically active compounds
Z Jakopin, MS Dolenc
Current medicinal chemistry 17 (7), 651-671, 2010
482010
Synthesis of 3, 5-disubstituted 1, 2, 4-oxadiazoles as peptidomimetic building blocks
Ž Jakopin, R Roškar, MS Dolenc
Tetrahedron letters 48 (8), 1465-1468, 2007
462007
Risks associated with fat burners: a toxicological perspective
Ž Jakopin
Food and Chemical Toxicology 123, 205-224, 2019
442019
Murabutide revisited: a review of its pleiotropic biological effects
Z Jakopin
Current medicinal chemistry 20 (16), 2068-2079, 2013
432013
Discovery of nanomolar desmuramylpeptide agonists of the innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) possessing …
M Gobec, T Tomašič, A Štimac, R Frkanec, J Trontelj, M Anderluh, ...
Journal of medicinal chemistry 61 (7), 2707-2724, 2018
412018
Immunomodulatory properties of novel nucleotide oligomerization domain 2 (Nod2) agonistic desmuramyldipeptides
Z Jakopin, M Gobec, I Mlinarič-Raščan, M Sollner Dolenc
Journal of medicinal chemistry 55 (14), 6478-6488, 2012
402012
Harnessing the untapped potential of nucleotide‐binding oligomerization domain ligands for cancer immunotherapy
S Nabergoj, I Mlinarič‐Raščan, Ž Jakopin
Medicinal research reviews 39 (5), 1447-1484, 2019
392019
Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2
M Gobec, I Mlinarič-Raščan, MS Dolenc, Ž Jakopin
European Journal of Medicinal Chemistry 116, 1-12, 2016
342016
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