| The NPY system in stress, anxiety and depression M Heilig Neuropeptides 38 (4), 213-224, 2004 | 758 | 2004 |
| Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides C Wahlestedt, EM Pich, GF Koob, F Yee, M Heilig Science 259 (5094), 528-531, 1993 | 712 | 1993 |
| Alcohol use disorders AF Carvalho, M Heilig, A Perez, C Probst, J Rehm The Lancet 394 (10200), 781-792, 2019 | 646 | 2019 |
| A key role for corticotropin-releasing factor in alcohol dependence M Heilig, GF Koob Trends in neurosciences 30 (8), 399-406, 2007 | 604 | 2007 |
| 1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial J Kakko, KD Svanborg, MJ Kreek, M Heilig The Lancet 361 (9358), 662-668, 2003 | 590 | 2003 |
| Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders A Holmes, M Heilig, NMJ Rupniak, T Steckler, G Griebel Trends in pharmacological sciences 24 (11), 580-588, 2003 | 526 | 2003 |
| Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? M Heilig, M Egli, JC Crabbe, HC Becker Addiction biology 15 (2), 169-184, 2010 | 474 | 2010 |
| Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models M Heilig, B Söderpalm, JA Engel, E Widerlöv Psychopharmacology 98, 524-529, 1989 | 466 | 1989 |
| Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects M Heilig, S McLeod, M Brot, SC Heinrichs, F Menzaghi, GF Koob, ... Neuropsychopharmacology 8 (4), 357-363, 1993 | 458 | 1993 |
| Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms M Heilig, M Egli Pharmacology & therapeutics 111 (3), 855-876, 2006 | 455 | 2006 |
| Requirement of central ghrelin signaling for alcohol reward E Jerlhag, E Egecioglu, S Landgren, N Salomé, M Heilig, D Moechars, ... Proceedings of the National Academy of Sciences 106 (27), 11318-11323, 2009 | 448 | 2009 |
| Corticotropin-releasing factor and neuropeptide Y: role in emotional integration M Heilig, GF Koob, R Ekman, KT Britton Trends in neurosciences 17 (2), 80-85, 1994 | 428 | 1994 |
| Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression A Thorsell, M Michalkiewicz, Y Dumont, R Quirion, L Caberlotto, ... Proceedings of the National Academy of Sciences 97 (23), 12852-12857, 2000 | 399 | 2000 |
| Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats LF Vendruscolo, E Barbier, JE Schlosburg, KK Misra, TW Whitfield, ... Journal of Neuroscience 32 (22), 7563-7571, 2012 | 353 | 2012 |
| Long‐lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol R Rimondini, C Arlinde, W Sommer, M Heilig The FASEB journal 16 (1), 27-35, 2002 | 352 | 2002 |
| Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence WH Sommer, R Rimondini, AC Hansson, PA Hipskind, DR Gehlert, ... Biological psychiatry 63 (2), 139-145, 2008 | 344 | 2008 |
| Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat C Wahlestedt, G Skagerberg, R Ekman, M Heilig, F Sundler, R Håkanson Brain research 417 (1), 33-38, 1987 | 336 | 1987 |
| A genetic determinant of the striatal dopamine response to alcohol in men VA Ramchandani, J Umhau, FJ Pavon, V Ruiz-Velasco, W Margas, H Sun, ... Molecular psychiatry 16 (8), 809-817, 2011 | 331 | 2011 |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse GR Breese, R Sinha, M Heilig Pharmacology & therapeutics 129 (2), 149-171, 2011 | 324 | 2011 |
| Genetic polymorphism of alcohol dehydrogenase in europeans: TheADH2* 2allele decreases the risk for alcoholism and is associated withADH3 E Borràs, C Coutelle, A Rosell, F Fernández-Muixi, M Broch, B Crosas, ... Hepatology 31 (4), 984-989, 2000 | 313 | 2000 |