From genome-wide associations to candidate causal variants by statistical fine-mapping DJ Schaid, W Chen, NB Larson Nature Reviews Genetics 19 (8), 491-504, 2018 | 973 | 2018 |
Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults KA Aberg, JL McClay, S Nerella, S Clark, G Kumar, W Chen, ... JAMA psychiatry 71 (3), 255-264, 2014 | 257 | 2014 |
Fine mapping causal variants with an approximate Bayesian method using marginal test statistics W Chen, BR Larrabee, IG Ovsyannikova, RB Kennedy, IH Haralambieva, ... Genetics 200 (3), 719-736, 2015 | 254 | 2015 |
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity PWF Karmaus, X Chen, SA Lim, AA Herrada, TLM Nguyen, B Xu, ... Nature 565 (7737), 101-105, 2019 | 188 | 2019 |
Genetic risk for subsequent neoplasms among long-term survivors of childhood cancer Z Wang, CL Wilson, J Easton, A Thrasher, H Mulder, Q Liu, DJ Hedges, ... Journal of Clinical Oncology 36 (20), 2078-2087, 2018 | 147 | 2018 |
UMI-count modeling and differential expression analysis for single-cell RNA sequencing W Chen, Y Li, J Easton, D Finkelstein, G Wu, X Chen Genome biology 19, 1-17, 2018 | 137 | 2018 |
Accurate genomic variant detection in single cells with primary template-directed amplification V Gonzalez-Pena, S Natarajan, Y Xia, D Klein, R Carter, Y Pang, ... Proceedings of the National Academy of Sciences 118 (24), e2024176118, 2021 | 132 | 2021 |
Automated ventricular systems segmentation in brain CT images by combining low-level segmentation and high-level template matching W Chen, R Smith, SY Ji, KR Ward, K Najarian BMC medical informatics and decision making 9, 1-14, 2009 | 83 | 2009 |
Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells K Yang, DB Blanco, X Chen, P Dash, G Neale, C Rosencrance, J Easton, ... Science immunology 3 (25), eaas9818, 2018 | 80 | 2018 |
Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: meta-analysis of three treatment cohorts J Ward, N Graham, RJ Strawbridge, A Ferguson, G Jenkins, W Chen, ... PloS one 13 (9), e0203896, 2018 | 72 | 2018 |
A review of single-cell rna-seq annotation, integration, and cell–cell communication C Cheng, W Chen, H Jin, X Chen Cells 12 (15), 1970, 2023 | 66 | 2023 |
Incorporating functional annotations for fine-mapping causal variants in a Bayesian framework using summary statistics W Chen, SK McDonnell, SN Thibodeau, LS Tillmans, DJ Schaid Genetics 204 (3), 933-958, 2016 | 60 | 2016 |
Intracranial pressure level prediction in traumatic brain injury by extracting features from multiple sources and using machine learning methods W Chen, C Cockrell, KR Ward, K Najarian 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2010 | 57 | 2010 |
XAF1 as a modifier of p53 function and cancer susceptibility EM Pinto, BC Figueiredo, W Chen, HCR Galvao, MN Formiga, ... Science advances 6 (26), eaba3231, 2020 | 56 | 2020 |
Small sample kernel association tests for human genetic and microbiome association studies J Chen, W Chen, N Zhao, MC Wu, DJ Schaid Genetic epidemiology 40 (1), 5-19, 2016 | 54 | 2016 |
Automated measurement of brain injury indices using brain CT images, injury data, and machine learning K Najarian, W Chen, KR Ward US Patent 10,303,986, 2019 | 53 | 2019 |
Automated midline shift and intracranial pressure estimation based on brain CT images W Chen, A Belle, C Cockrell, KR Ward, K Najarian Journal of visualized experiments: JoVE, 3871, 2013 | 39 | 2013 |
Recent advances and challenges of rare variant association analysis in the biobank sequencing era W Chen, BJ Coombes, NB Larson Frontiers in genetics 13, 1014947, 2022 | 38 | 2022 |
A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing W Chen, S Zhang, J Williams, B Ju, B Shaner, J Easton, G Wu, X Chen Computational and Structural Biotechnology Journal 18, 861-873, 2020 | 35 | 2020 |
Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data C Cheng, J Easton, C Rosencrance, Y Li, B Ju, J Williams, HL Mulder, ... Nucleic Acids Research 47 (22), e143-e143, 2019 | 35 | 2019 |