A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels IE Dick, MR Tadross, H Liang, LH Tay, W Yang, DT Yue Nature 451 (7180), 830-834, 2008 | 293 | 2008 |
Mechanism of local and global Ca2+ sensing by calmodulin in complex with a Ca2+ channel MR Tadross, IE Dick, DT Yue Cell 133 (7), 1228-1240, 2008 | 251 | 2008 |
Sodium channel blockade may contribute to the analgesic efficacy of antidepressants IE Dick, RM Brochu, Y Purohit, GJ Kaczorowski, WJ Martin, BT Priest The Journal of Pain 8 (4), 315-324, 2007 | 218 | 2007 |
Calmodulin mutations associated with long QT syndrome prevent inactivation of cardiac L-type Ca2+ currents and promote proarrhythmic behavior in ventricular myocytes WB Limpitikul, IE Dick, R Joshi-Mukherjee, MT Overgaard, AL George Jr, ... Journal of molecular and cellular cardiology 74, 115-124, 2014 | 184 | 2014 |
A precision medicine approach to the rescue of function on malignant calmodulinopathic long-QT syndrome WB Limpitikul, IE Dick, DJ Tester, NJ Boczek, P Limphong, W Yang, ... Circulation research 120 (1), 39-48, 2017 | 163 | 2017 |
Apocalmodulin itself promotes ion channel opening and Ca2+ regulation PJ Adams, M Ben-Johny, IE Dick, T Inoue, DT Yue Cell 159 (3), 608-622, 2014 | 106 | 2014 |
Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes JP Felix, BS Williams, BT Priest, RM Brochu, IE Dick, VA Warren, L Yan, ... Assay and drug development technologies 2 (3), 260-268, 2004 | 104 | 2004 |
Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca2+-dependent inactivation IE Dick, R Joshi-Mukherjee, W Yang, DT Yue Nature communications 7 (1), 10370, 2016 | 101 | 2016 |
Towards a unified theory of calmodulin regulation (calmodulation) of voltage-gated calcium and sodium channels M Ben-Johny, I E Dick, L Sang, W B Limpitikul, P Wei Kang, J Niu, ... Current molecular pharmacology 8 (2), 188-205, 2015 | 67 | 2015 |
Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats RM Brochu, IE Dick, JW Tarpley, E McGowan, D Gunner, J Herrington, ... Molecular pharmacology 69 (3), 823-832, 2006 | 63 | 2006 |
Nanodomain Ca2+ of Ca2+ channels detected by a tethered genetically encoded Ca2+ sensor LH Tay, IE Dick, W Yang, M Mank, O Griesbeck, DT Yue Nature communications 3 (1), 778, 2012 | 58 | 2012 |
A high-capacity membrane potential FRET-based assay for NaV1. 8 channels CJ Liu, BT Priest, RM Bugianesi, PM Dulski, JP Felix, IE Dick, RM Brochu, ... Assay and drug development technologies 4 (1), 37-48, 2006 | 45 | 2006 |
Biophysical and pharmacological properties of the voltage‐gated potassium current of human pancreatic β‐cells J Herrington, M Sanchez, D Wunderler, L Yan, RM Bugianesi, IE Dick, ... The Journal of Physiology 567 (1), 159-175, 2005 | 45 | 2005 |
An autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca2+-dependent regulation WB Limpitikul, IE Dick, M Ben-Johny, DT Yue Scientific reports 6 (1), 27235, 2016 | 40 | 2016 |
Protein kinase A modulation of CaV1.4 calcium channels L Sang, IE Dick, DT Yue Nature communications 7 (1), 12239, 2016 | 38 | 2016 |
The Blazhko effect of RR Lyrae in 1996 HA Smith, JA Church, J Fournier, J Lisle, P Gay, K Kolenberg, BW Carney, ... Publications of the Astronomical Society of the Pacific 115 (803), 43, 2003 | 38 | 2003 |
A disubstituted succinamide is a potent sodium channel blocker with efficacy in a rat pain model BT Priest, ML Garcia, RE Middleton, RM Brochu, S Clark, G Dai, IE Dick, ... Biochemistry 43 (30), 9866-9876, 2004 | 36 | 2004 |
Infanticide vs. inherited cardiac arrhythmias M Brohus, T Arsov, DA Wallace, HH Jensen, M Nyegaard, L Crotti, ... EP Europace 23 (3), 441-450, 2021 | 35 | 2021 |
Allosteric regulators selectively prevent Ca2+-feedback of CaV and NaV channels J Niu, IE Dick, W Yang, MA Bamgboye, DT Yue, G Tomaselli, T Inoue, ... Elife 7, e35222, 2018 | 33 | 2018 |
Following optogenetic dimerizers and quantitative prospects J Niu, MB Johny, IE Dick, T Inoue Biophysical journal 111 (6), 1132-1140, 2016 | 30 | 2016 |