| Core signaling pathways in human pancreatic cancers revealed by global genomic analyses S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1801-1806, 2008 | 4733 | 2008 |
| Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti–PD-1 therapy JM Taube, A Klein, JR Brahmer, H Xu, X Pan, JH Kim, L Chen, DM Pardoll, ... Clinical cancer research 20 (19), 5064-5074, 2014 | 2600 | 2014 |
| Detection and localization of surgically resectable cancers with a multi-analyte blood test JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ... Science 359 (6378), 926-930, 2018 | 2561 | 2018 |
| Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape JM Taube, RA Anders, GD Young, H Xu, R Sharma, TL McMiller, S Chen, ... Science translational medicine 4 (127), 127ra37-127ra37, 2012 | 2463 | 2012 |
| Altered telomeres in tumors with ATRX and DAXX mutations CM Heaphy, RF De Wilde, Y Jiao, AP Klein, BH Edil, C Shi, C Bettegowda, ... Science 333 (6041), 425-425, 2011 | 1216 | 2011 |
| DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ... Journal of clinical oncology 27 (11), 1806-1813, 2009 | 1196 | 2009 |
| Recent progress in pancreatic cancer CL Wolfgang, JM Herman, DA Laheru, AP Klein, MA Erdek, EK Fishman, ... CA: a cancer journal for clinicians 63 (5), 318-348, 2013 | 1145 | 2013 |
| Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ... Science 324 (5924), 217-217, 2009 | 1041 | 2009 |
| Prevalence of unsuspected pancreatic cysts on MDCT TA Laffan, KM Horton, AP Klein, B Berlanstein, SS Siegelman, ... American Journal of Roentgenology 191 (3), 802-807, 2008 | 1005 | 2008 |
| Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development J Wu, H Matthaei, A Maitra, M Dal Molin, LD Wood, JR Eshleman, ... Science translational medicine 3 (92), 92ra66-92ra66, 2011 | 876 | 2011 |
| Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds AP Klein, KA Brune, GM Petersen, M Goggins, AC Tersmette, ... Cancer research 64 (7), 2634-2638, 2004 | 870 | 2004 |
| Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer L Amundadottir, P Kraft, RZ Stolzenberg-Solomon, CS Fuchs, ... Nature genetics 41 (9), 986-990, 2009 | 802 | 2009 |
| Frequent detection of pancreatic lesions in asymptomatic high-risk individuals MI Canto, RH Hruban, EK Fishman, IR Kamel, R Schulick, Z Zhang, ... Gastroenterology 142 (4), 796-804, 2012 | 746 | 2012 |
| Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors AP Klein Nature reviews Gastroenterology & hepatology 18 (7), 493-502, 2021 | 742 | 2021 |
| Detectable clonal mosaicism and its relationship to aging and cancer KB Jacobs, M Yeager, W Zhou, S Wacholder, Z Wang, ... Nature genetics 44 (6), 651-658, 2012 | 681 | 2012 |
| Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways J Wu, Y Jiao, M Dal Molin, A Maitra, RF De Wilde, LD Wood, JR Eshleman, ... Proceedings of the National Academy of Sciences 108 (52), 21188-21193, 2011 | 681 | 2011 |
| Expression of Yes-associated protein in common solid tumors AA Steinhardt, MF Gayyed, AP Klein, J Dong, A Maitra, D Pan, ... Human pathology 39 (11), 1582-1589, 2008 | 681 | 2008 |
| A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22. 1, 1q32. 1 and 5p15. 33 GM Petersen, L Amundadottir, CS Fuchs, P Kraft, ... Nature genetics 42 (3), 224-228, 2010 | 664 | 2010 |
| ATM Mutations in Patients with Hereditary Pancreatic Cancer NJ Roberts, Y Jiao, J Yu, L Kopelovich, GM Petersen, ML Bondy, ... Cancer discovery 2 (1), 41-46, 2012 | 590 | 2012 |
| Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers JD Cohen, AA Javed, C Thoburn, F Wong, J Tie, P Gibbs, CM Schmidt, ... Proceedings of the National Academy of Sciences 114 (38), 10202-10207, 2017 | 560 | 2017 |
Ralph HrubanJohns Hopkins University在 jhmi.edu 的电子邮件经过验证