Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes SFA Grant, G Thorleifsson, I Reynisdottir, R Benediktsson, A Manolescu, ... Nature genetics 38 (3), 320-323, 2006 | 2880 | 2006 |
Genetics of gene expression and its effect on disease V Emilsson, G Thorleifsson, B Zhang, AS Leonardson, F Zink, J Zhu, ... Nature 452 (7186), 423-428, 2008 | 1617 | 2008 |
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. MH Lee, I Reynisdottir, J Massague Genes & development 9 (6), 639-649, 1995 | 1319 | 1995 |
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes V Steinthorsdottir, G Thorleifsson, I Reynisdottir, R Benediktsson, ... Nature genetics 39 (6), 770-775, 2007 | 1272 | 2007 |
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. I Reynisdottir, K Polyak, A Iavarone, J Massague Genes & development 9 (15), 1831-1845, 1995 | 1253 | 1995 |
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution A Helgason, S Pálsson, G Thorleifsson, SFA Grant, V Emilsson, ... Nature genetics 39 (2), 218-225, 2007 | 657 | 2007 |
The subcellular locations of p15 (Ink4b) and p27 (Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. I Reynisdóttir, J Massague Genes & development 11 (4), 492-503, 1997 | 462 | 1997 |
Linkage of Osteoporosis to Chromosome 20p12 and Association to BMP2 U Styrkarsdottir, JB Cazier, A Kong, O Rolfsson, H Larsen, E Bjarnadottir, ... PLoS biology 1 (3), e69, 2003 | 352 | 2003 |
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. J Bargonetti, I Reynisdottir, PN Friedman, C Prives Genes & development 6 (10), 1886-1898, 1992 | 348 | 1992 |
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34–q35. 2 I Reynisdottir, G Thorleifsson, R Benediktsson, G Sigurdsson, V Emilsson, ... The American Journal of Human Genetics 73 (2), 323-335, 2003 | 260 | 2003 |
Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer JI Kiiski, LM Pelttari, S Khan, ES Freysteinsdottir, I Reynisdottir, SN Hart, ... Proceedings of the National Academy of Sciences 111 (42), 15172-15177, 2014 | 226 | 2014 |
Subclinical intestinal inflammation: an inherited abnormality in Crohn’s disease relatives? B Thjodleifsson, G Sigthorsson, N Cariglia, I Reynisdottir, ... Gastroenterology 124 (7), 1728-1737, 2003 | 213 | 2003 |
Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis I Bjarnason, KO Helgason, ÁJ Geirsson, G Sigthorsson, I Reynisdottir, ... Gastroenterology 125 (6), 1598-1605, 2003 | 88 | 2003 |
The effect of PLC-γ2 inhibitors on the growth of human tumour cells L Feng, I Reynisdóttir, J Reynisson European journal of medicinal chemistry 54, 463-469, 2012 | 73 | 2012 |
High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer I Reynisdottir, A Arason, BO Einarsdottir, H Gunnarsson, J Staaf, ... Cancer medicine 2 (4), 437-446, 2013 | 44 | 2013 |
The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714predict adverse outcome for breast cancer patients ET Gudmundsdottir, RB Barkardottir, A Arason, H Gunnarsson, ... BMC cancer 12, 1-10, 2012 | 43 | 2012 |
Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways A Amirfallah, H Knutsdottir, A Arason, B Hilmarsdottir, OT Johannsson, ... PloS one 16 (11), e0260327, 2021 | 34 | 2021 |
Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitro I Reynisdóttir, DR O'Reilly, LK Miller, C Prives Journal of virology 64 (12), 6234-6245, 1990 | 29 | 1990 |
Identification of anticancer agents based on the thieno [2, 3-b] pyridine and 1H-pyrazole molecular scaffolds C Eurtivong, I Reynisdóttir, S Kuczma, DP Furkert, MA Brimble, ... Bioorganic & medicinal chemistry 24 (16), 3521-3526, 2016 | 23 | 2016 |
The BRCA1 c.4096+3A>G Variant Displays Classical Characteristics of Pathogenic BRCA1 Mutations in Hereditary Breast and Ovarian Cancers, But Still Allows … A Arason, BA Agnarsson, G Johannesdottir, OT Johannsson, ... Genes 10 (11), 882, 2019 | 17 | 2019 |