| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13664* | 2021 |
| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6064 | 2018 |
| Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4587 | 2013 |
| Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3408 | 2009 |
| Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ... Cell Death & Differentiation 19 (1), 107-120, 2012 | 3227 | 2012 |
| TFEB links autophagy to lysosomal biogenesis C Settembre, C Di Malta, VA Polito, MG Arencibia, F Vetrini, S Erdin, ... science 332 (6036), 1429-1433, 2011 | 3184 | 2011 |
| Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ... Nature genetics 36 (6), 585-595, 2004 | 2848 | 2004 |
| Autophagy and aging DC Rubinsztein, G Mariño, G Kroemer Cell 146 (5), 682-695, 2011 | 2525 | 2011 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2470 | 2019 |
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2249 | 2011 |
| Regulation of mammalian autophagy in physiology and pathophysiology B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ... Physiological reviews 90 (4), 1383-1435, 2010 | 2127 | 2010 |
| The roles of intracellular protein-degradation pathways in neurodegeneration DC Rubinsztein Nature 443 (7113), 780-786, 2006 | 2070 | 2006 |
| α-Synuclein is degraded by both autophagy and the proteasome JL Webb, B Ravikumar, J Atkins, JN Skepper, DC Rubinsztein Journal of Biological Chemistry 278 (27), 25009-25013, 2003 | 1801 | 2003 |
| Molecular definitions of autophagy and related processes L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ... The EMBO journal 36 (13), 1811-1836, 2017 | 1653 | 2017 |
| Autophagy modulation as a potential therapeutic target for diverse diseases DC Rubinsztein, P Codogno, B Levine Nature reviews Drug discovery 11 (9), 709-730, 2012 | 1646 | 2012 |
| Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1454 | 2018 |
| Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy B Ravikumar, R Duden, DC Rubinsztein Human molecular genetics 11 (9), 1107-1117, 2002 | 1368 | 2002 |
| Autophagy in malignant transformation and cancer progression L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ... The EMBO journal 34 (7), 856-880, 2015 | 1304 | 2015 |
| Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein S Sarkar, JE Davies, Z Huang, A Tunnacliffe, DC Rubinsztein Journal of Biological Chemistry 282 (8), 5641-5652, 2007 | 1266 | 2007 |
| Potential therapeutic applications of autophagy DC Rubinsztein, JE Gestwicki, LO Murphy, DJ Klionsky Nature reviews Drug discovery 6 (4), 304-312, 2007 | 1259 | 2007 |
