Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina H Petrs-Silva, A Dinculescu, Q Li, WT Deng, J Pang, SH Min, V Chiodo, ... Molecular therapy 19 (2), 293-301, 2011 | 310 | 2011 |
Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression LI Zhong, B Li, G Jayandharan, CS Mah, L Govindasamy, ... Virology 381 (2), 194-202, 2008 | 289 | 2008 |
Basic biology of adeno-associated virus (AAV) vectors used in gene therapy B Balakrishnan, G R. Jayandharan Current gene therapy 14 (2), 86-100, 2014 | 255 | 2014 |
Genetic diagnosis of haemophilia and other inherited bleeding disorders F Peyvandi, G Jayandharan, M Chandy, A Srivastava, SM Nakaya, ... Haemophilia 12, 82-89, 2006 | 202 | 2006 |
Innate immune responses to AAV vectors GL Rogers, AT Martino, GV Aslanidi, GR Jayandharan, A Srivastava, ... Frontiers in microbiology 2, 194, 2011 | 194 | 2011 |
High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines DM Markusic, RW Herzog, GV Aslanidi, BE Hoffman, B Li, M Li, ... Molecular Therapy 18 (12), 2048-2056, 2010 | 166 | 2010 |
Adeno‐associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them S Hareendran, B Balakrishnan, D Sen, S Kumar, A Srivastava, ... Reviews in medical virology 23 (6), 399-413, 2013 | 130 | 2013 |
Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3 C Ling, Y Lu, JK Kalsi, GR Jayandharan, B Li, W Ma, B Cheng, SWY Gee, ... Human gene therapy 21 (12), 1741-1747, 2010 | 128 | 2010 |
Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle C Qiao, W Zhang, Z Yuan, JH Shin, J Li, GR Jayandharan, L Zhong, ... Human gene therapy 21 (10), 1343-1348, 2010 | 109 | 2010 |
Bioengineering of AAV2 Capsid at Specific Serine, Threonine, or Lysine Residues Improves Its Transduction Efficiency in Vitro and in Vivo N Gabriel, S Hareendran, D Sen, RA Gadkari, G Sudha, R Selot, ... Human gene therapy methods 24 (2), 80-93, 2013 | 107 | 2013 |
The phenotypic heterogeneity of severe hemophilia GR Jayandharan, A Srivastava Seminars in thrombosis and hemostasis 34 (01), 128-141, 2008 | 107 | 2008 |
Post‐translational modifications in capsid proteins of recombinant adeno‐associated virus (AAV) 1‐rh10 serotypes B Mary, S Maurya, S Arumugam, V Kumar, GR Jayandharan The FEBS journal 286 (24), 4964-4981, 2019 | 99 | 2019 |
Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of … G Jayandharan, RV Shaji, S Baidya, SC Nair, M Chandy, A Srivastava Haemophilia 11 (5), 481-491, 2005 | 91 | 2005 |
High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy M Li, GR Jayandharan, B Li, C Ling, W Ma, A Srivastava, L Zhong Human gene therapy 21 (11), 1527-1543, 2010 | 88 | 2010 |
Nuclear factor (NF)‐κB and its associated pathways are major molecular regulators of blood‐induced joint damage in a murine model of hemophilia D Sen, A Chapla, N Walter, V Daniel, A Srivastava, GR Jayandharan Journal of Thrombosis and Haemostasis 11 (2), 293-306, 2013 | 86 | 2013 |
Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo L Song, MA Kauss, E Kopin, M Chandra, T Ul-Hasan, E Miller, ... Cytotherapy 15 (8), 986-998, 2013 | 83 | 2013 |
Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine … C Ling, Y Wang, Y Lu, L Wang, GR Jayandharan, GV Aslanidi, B Li, ... Journal of virology 89 (2), 952-961, 2015 | 74 | 2015 |
Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming RA Rao, N Dhele, S Cheemadan, A Ketkar, GR Jayandharan, ... Scientific reports 5 (1), 8229, 2015 | 73 | 2015 |
Targeted Modifications in Adeno-Associated Virus Serotype 8 Capsid Improves Its Hepatic Gene Transfer Efficiency In Vivo D Sen, RA Gadkari, G Sudha, N Gabriel, YS Kumar, R Selot, R Samuel, ... Human gene therapy methods 24 (2), 104-116, 2013 | 70 | 2013 |
High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine … L Song, X Li, GR Jayandharan, Y Wang, GV Aslanidi, C Ling, L Zhong, ... PLoS One 8 (3), e58757, 2013 | 65 | 2013 |