The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome PJ Bosma, JR Chowdhury, C Bakker, S Gantla, A de Boer, BA Oostra, ... New England Journal of Medicine 333 (18), 1171-1175, 1995 | 1883 | 1995 |
Nitrite and nitrate determinations in plasma: a critical evaluation H Moshage, B Kok, JR Huizenga, PL Jansen Clinical chemistry 41 (6), 892-896, 1995 | 1581 | 1995 |
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. M Müller, C Meijer, GJ Zaman, P Borst, RJ Scheper, NH Mulder, ... Proceedings of the National Academy of Sciences 91 (26), 13033-13037, 1994 | 786 | 1994 |
Bile acid receptors as targets for drug development FG Schaap, M Trauner, PLM Jansen Nature reviews Gastroenterology & hepatology 11 (1), 55-67, 2014 | 772 | 2014 |
New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond U Beuers, M Trauner, P Jansen, R Poupon Journal of hepatology 62 (1), S25-S37, 2015 | 626 | 2015 |
Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man. PJ Bosma, J Seppen, B Goldhoorn, C Bakker, RPO Elferink, ... Journal of Biological Chemistry 269 (27), 17960-17964, 1994 | 561 | 1994 |
Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized study HW Reesink, S Zeuzem, CJ Weegink, N Forestier, A Van Vliet, ... Gastroenterology 131 (4), 997-1002, 2006 | 527 | 2006 |
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis PLM Jansen, SS Strautnieks, E Jacquemin, M Hadchouel, EM Sokal, ... Gastroenterology 117 (6), 1370-1379, 1999 | 524 | 1999 |
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport RPJO Elferink, DKF Meijer, F Kuipers, PLM Jansen, AK Groen, ... Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1241 (2), 215-268, 1995 | 503 | 1995 |
Molecular aspects of hepatobiliary transport M Muller, PL Jansen American Journal of Physiology-Gastrointestinal and Liver Physiology 272 (6 …, 1997 | 464 | 1997 |
Up–Regulation of the Multidrug Resistance Genes, Mrp1AndMdr1b, and Down–Regulation of the Organic Anion Transporter, Mrp2, and the Bile Salt Transporter, Spgp, in Endotoxemic … TA Vos, GJ Hooiveld, H Koning, S Childs, DK Meijer, H Moshage, ... Hepatology 28 (6), 1637-1644, 1998 | 457 | 1998 |
Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport PLM Jansen, WH Peters, WH Lamers Hepatology 5 (4), 573-579, 1985 | 440 | 1985 |
The biliary HCO3− umbrella: A unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies U Beuers, S Hohenester, LJM de Buy Wenniger, AE Kremer, PLM Jansen, ... Hepatology 52 (4), 1489-1496, 2010 | 416 | 2010 |
Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11 SWC van Mil, WL van der Woerd, G van der Brugge, E Sturm, ... Gastroenterology 127 (2), 379-384, 2004 | 416 | 2004 |
Increased cancer risk after liver transplantation: a population-based study EB Haagsma, VE Hagens, M Schaapveld, AP van den Berg, ... Journal of hepatology 34 (1), 84-91, 2001 | 397 | 2001 |
Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump JRM Plass, O Mol, J Heegsma, M Geuken, KN Faber, PLM Jansen, ... Hepatology 35 (3), 589-596, 2002 | 366 | 2002 |
The UDP glucuronosyltransferase gene super family: suggested nomenclature based on evolutionary divergence B Burchell, DW Nebert, DR Nelson, KW Bock, T Iyanagi, PL Jansen, ... DNA and Cell Biology 10 (7), 487-494, 1991 | 344 | 1991 |
ATP‐and glutathione‐dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1 J Renes, EGE De Vries, EF Nienhuis, PLM Jansen, M Müller British journal of pharmacology 126 (3), 681-688, 1999 | 340 | 1999 |
The ascending pathophysiology of cholestatic liver disease PLM Jansen, A Ghallab, N Vartak, R Reif, FG Schaap, J Hampe, ... Hepatology 65 (2), 722-738, 2017 | 325 | 2017 |
High expression of the bile salt‐homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis FG Schaap, NA van der Gaag, DJ Gouma, PLM Jansen Hepatology 49 (4), 1228-1235, 2009 | 321 | 2009 |