Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism J Fadista, P Vikman, EO Laakso, IG Mollet, JL Esguerra, J Taneera, ... Proceedings of the National Academy of Sciences 111 (38), 13924-13929, 2014 | 507 | 2014 |
Whole-genome bisulfite sequencing of human pancreatic islets reveals novel differentially methylated regions in type 2 diabetes pathogenesis P Volkov, K Bacos, JK Ofori, JLS Esguerra, L Eliasson, T Rönn, C Ling Diabetes 66 (4), 1074-1085, 2017 | 175 | 2017 |
Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell JK Ofori, VA Salunkhe, A Bagge, N Vishnu, M Nagao, H Mulder, ... Scientific Reports 7 (1), 44986, 2017 | 90 | 2017 |
MicroRNAs in islet hormone secretion JLS Esguerra, M Nagao, JK Ofori, A Wendt, L Eliasson Diabetes, Obesity and Metabolism 20, 11-19, 2018 | 61 | 2018 |
Potential protection against type 2 diabetes in obesity through lower CD36 expression and improved exocytosis in β-cells M Nagao, JLS Esguerra, A Asai, JK Ofori, A Edlund, A Wendt, H Sugihara, ... Diabetes 69 (6), 1193-1205, 2020 | 56 | 2020 |
Modulation of microRNA‐375 expression alters voltage‐gated Na+ channel properties and exocytosis in insulin‐secreting cells VA Salunkhe, JLS Esguerra, JK Ofori, IG Mollet, M Braun, M Stoffel, ... Acta physiologica 213 (4), 882-892, 2015 | 56 | 2015 |
Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA JLS Esguerra, JK Ofori, M Nagao, Y Shuto, A Karagiannopoulos, ... Molecular Metabolism 32, 160-167, 2020 | 55 | 2020 |
Glucolipotoxicity alters insulin secretion via epigenetic changes in human islets E Hall, J Jönsson, JK Ofori, P Volkov, A Perfilyev, M Dekker Nitert, ... Diabetes 68 (10), 1965-1974, 2019 | 46 | 2019 |
MiR‐335 overexpression impairs insulin secretion through defective priming of insulin vesicles VA Salunkhe, JK Ofori, NR Gandasi, SA Salö, S Hansson, ME Andersson, ... Physiological reports 5 (21), e13493, 2017 | 36 | 2017 |
Dual effect of rosuvastatin on glucose homeostasis through improved insulin sensitivity and reduced insulin secretion VA Salunkhe, IG Mollet, JK Ofori, HA Malm, JLS Esguerra, TM Reinbothe, ... EBioMedicine 10, 185-194, 2016 | 34 | 2016 |
Human islet microRNA-200c is elevated in type 2 diabetes and targets the transcription factor ETV5 to reduce insulin secretion JK Ofori, A Karagiannopoulos, M Nagao, E Westholm, S Ramadan, ... Diabetes 71 (2), 275-284, 2022 | 31 | 2022 |
Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets K Bacos, A Perfilyev, A Karagiannopoulos, E Cowan, JK Ofori, ... The Journal of clinical investigation 133 (4), 2023 | 30 | 2023 |
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes T Rönn, JK Ofori, A Perfilyev, A Hamilton, K Pircs, F Eichelmann, ... Nature Communications 14 (1), 8040, 2023 | 25 | 2023 |
Effect of IPTp on Plasmodium falciparum antibody levels among pregnant women and their babies in a sub-urban coastal area in Ghana JK Stephens, E Kyei-Baafour, EK Dickson, JK Ofori, MF Ofori, ML Wilson, ... Malaria journal 16, 1-10, 2017 | 20 | 2017 |
The highly expressed calcium‐insensitive synaptotagmin‐11 and synaptotagmin‐13 modulate insulin secretion JK Ofori, A Karagiannopoulos, M Barghouth, M Nagao, ME Andersson, ... Acta Physiologica 236 (1), e13857, 2022 | 10 | 2022 |
MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells VA Salunkhe, J Ofori, NR Gandasi, SA Salö, A Wendt, S Barg, ... Diabetologia 58 (Suppl. 1), 128-128, 2015 | 5 | 2015 |
Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines JK Ofori, HA Malm, IG Mollet, L Eliasson, JLS Esguerra PeerJ 5, e3503, 2017 | 3 | 2017 |
Effects of mating system on adaptive potential for leaf morphology in Crepis tectorum (Asteraceae) S Andersson, JK Ofori Annals of botany 112 (5), 947-955, 2013 | 3 | 2013 |
Glucocorticoid-mediated induction of ZBTB16 affects insulin secretion in human islets and EndoC-βH1 β-cells A Karagiannopoulos, E Westholm, JK Ofori, E Cowan, JLS Esguerra, ... Iscience 26 (5), 2023 | 2 | 2023 |
MicroRNA 29 modulates β‐cell mitochondrial metabolism and insulin secretion via underlying miR‐29‐OXPHOS complex pathways E Cowan, J Sun, A Hamilton, S Ruhrmann, A Karagiannopoulos, ... Acta Physiologica 240 (8), e14180, 2024 | 1 | 2024 |