Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability D Fukumura, T Gohongi, A Kadambi, Y Izumi, J Ang, CO Yun, DG Buerk, ... Proceedings of the National Academy of Sciences 98 (5), 2604-2609, 2001 | 1224 | 2001 |
Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy JH Kim, YS Lee, H Kim, JH Huang, AR Yoon, CO Yun Journal of the National Cancer Institute 98 (20), 1482-1493, 2006 | 260 | 2006 |
Strategies to increase drug penetration in solid tumors IK Choi, R Strauss, M Richter, CO Yun, A Lieber Frontiers in oncology 3, 193, 2013 | 198 | 2013 |
Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model YS Lee, JH Kim, KJ Choi, IK Choi, H Kim, S Cho, BC Cho, CO Yun Clinical cancer research 12 (19), 5859-5868, 2006 | 180 | 2006 |
VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth JY Yoo, JH Kim, YG Kwon, EC Kim, NK Kim, HJ Choi, CO Yun Molecular Therapy 15 (2), 295-302, 2007 | 179 | 2007 |
Tumor–host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor β1 T Gohongi, D Fukumura, Y Boucher, CO Yun, GA Soff, C Compton, ... Nature medicine 5 (10), 1203-1208, 1999 | 179 | 1999 |
Evolution of oncolytic adenovirus for cancer treatment JW Choi, JS Lee, SW Kim, CO Yun Advanced drug delivery reviews 64 (8), 720-729, 2012 | 160 | 2012 |
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin Y Son, EH Kim, JY Kim, SU Kim, TK Kwon, AR Yoon, CO Yun, KS Choi Cancer research 67 (17), 8274-8284, 2007 | 160 | 2007 |
Chiral supraparticles for controllable nanomedicine J Yeom, PPG Guimaraes, HM Ahn, BK Jung, Q Hu, K McHugh, ... Advanced Materials 32 (1), 1903878, 2020 | 153 | 2020 |
Polymeric delivery systems for nucleic acid therapeutics: Approaching the clinic AIS van den Berg, CO Yun, RM Schiffelers, WE Hennink Journal of Controlled Release 331, 121-141, 2021 | 152 | 2021 |
Biodegradable inorganic nanovector: passive versus active tumor targeting in siRNA transportation DH Park, J Cho, OJ Kwon, CO Yun, JH Choy Angewandte chemie international edition 55 (14), 4582-4586, 2016 | 150 | 2016 |
Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A A Kadambi, C Mouta Carreira, C Yun, TP Padera, DE Dolmans, ... Cancer research 61 (6), 2404-2408, 2001 | 146 | 2001 |
Active targeting and safety profile of PEG-modified adenovirus conjugated with herceptin PH Kim, JH Sohn, JW Choi, Y Jung, SW Kim, S Haam, CO Yun Biomaterials 32 (9), 2314-2326, 2011 | 145 | 2011 |
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL JH Huang, SN Zhang, KJ Choi, IK Choi, JH Kim, M Lee, H Kim, CO Yun Molecular Therapy 18 (2), 264-274, 2010 | 143 | 2010 |
Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα IK Choi, JS Lee, SN Zhang, J Park, KM Lee, CH Sonn, CO Yun Gene therapy 18 (9), 898-909, 2011 | 137 | 2011 |
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect KJ Choi, JH Kim, YS Lee, J Kim, BS Suh, H Kim, S Cho, JH Sohn, GE Kim, ... Gene therapy 13 (13), 1010-1020, 2006 | 134 | 2006 |
Ad-mTERT-Δ19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell … E Kim, JH Kim, HY Shin, H Lee, JM Yang, J Kim, JH Sohn, H Kim, CO Yun Human gene therapy 14 (15), 1415-1428, 2003 | 134 | 2003 |
Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression T Koo, AR Yoon, HY Cho, S Bae, CO Yun, JS Kim Nucleic acids research 45 (13), 7897-7908, 2017 | 132 | 2017 |
Vascular endothelial growth factor (VEGF) signaling regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II … BW Kim, M Choi, YS Kim, H Park, HR Lee, CO Yun, EJ Kim, JS Choi, ... Cellular signalling 20 (4), 714-725, 2008 | 131 | 2008 |
Correlation of KIT and platelet-derived growth factor receptor α mutations with gene activation and expression profiles in gastrointestinal stromal tumors HJ Kang, SW Nam, H Kim, H Rhee, NG Kim, H Kim, WJ Hyung, SH Noh, ... Oncogene 24 (6), 1066-1074, 2005 | 131 | 2005 |