Biosynthesis of the Arabinogalactan‐Peptidoglycan Complex of Mycobacterium tuberculosiss DC Crick, PJ Brennan The mycobacterial cell envelope, 25-40, 2008 | 395 | 2008 |
Phosphatidylinositol is an essential phospholipid of mycobacteria M Jackson, DC Crick, PJ Brennan Journal of Biological Chemistry 275 (39), 30092-30099, 2000 | 278 | 2000 |
Multitarget drug discovery for tuberculosis and other infectious diseases K Li, LA Schurig-Briccio, X Feng, A Upadhyay, V Pujari, B Lechartier, ... Journal of medicinal chemistry 57 (7), 3126-3139, 2014 | 276 | 2014 |
Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan JB Raymond, S Mahapatra, DC Crick, MS Pavelka Journal of Biological Chemistry 280 (1), 326-333, 2005 | 264 | 2005 |
Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of … K Mikušová, H Huang, T Yagi, M Holsters, D Vereecke, W D'Haeze, ... Journal of bacteriology 187 (23), 8020-8025, 2005 | 261 | 2005 |
Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis W Li, A Upadhyay, FL Fontes, EJ North, Y Wang, DC Crans, ... Antimicrobial agents and chemotherapy 58 (11), 6413-6423, 2014 | 236 | 2014 |
Antiinfectives targeting enzymes and the proton motive force X Feng, W Zhu, LA Schurig-Briccio, S Lindert, C Shoen, R Hitchings, J Li, ... Proceedings of the National Academy of Sciences 112 (51), E7073-E7082, 2015 | 230 | 2015 |
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis B Phetsuksiri, M Jackson, H Scherman, M McNeil, GS Besra, AR Baulard, ... Journal of Biological Chemistry 278 (52), 53123-53130, 2003 | 215 | 2003 |
The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery. PJ Brennan, DC Crick Current topics in medicinal chemistry 7 (5), 475-488, 2007 | 201 | 2007 |
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria CL Gee, KG Papavinasasundaram, SR Blair, CE Baer, AM Falick, ... Science signaling 5 (208), ra7-ra7, 2012 | 187 | 2012 |
Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation DC Crick, DA Andres, CJ Waechter Biochemical and biophysical research communications 237 (3), 483-487, 1997 | 174 | 1997 |
Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non‐replicating persistence RK Dhiman, S Mahapatra, RA Slayden, ME Boyne, A Lenaerts, ... Molecular microbiology 72 (1), 85-97, 2009 | 173 | 2009 |
Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel “Mtb LipidDB” MJ Sartain, DL Dick, CD Rithner, DC Crick, JT Belisle Journal of lipid research 52 (5), 861-872, 2011 | 170 | 2011 |
Biosynthesis of the galactan component of the mycobacterial cell wall K Mikušová, T Yagi, R Stern, MR McNeil, GS Besra, DC Crick, ... Journal of Biological Chemistry 275 (43), 33890-33897, 2000 | 163 | 2000 |
Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways BC VanderVen, JD Harder, DC Crick, JT Belisle Science 309 (5736), 941-943, 2005 | 161 | 2005 |
Targeting the formation of the cell wall core of M. tuberculosis CE Barry, DC Crick, MR McNeil Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2007 | 156 | 2007 |
Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45 Y Ishizaki, C Hayashi, K Inoue, M Igarashi, Y Takahashi, V Pujari, ... Journal of Biological Chemistry 288 (42), 30309-30319, 2013 | 150 | 2013 |
Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis J Debnath, S Siricilla, B Wan, DC Crick, AJ Lenaerts, SG Franzblau, ... Journal of medicinal chemistry 55 (8), 3739-3755, 2012 | 145 | 2012 |
Metabolic Profiling of Lung Granuloma in Mycobacterium tuberculosis Infected Guinea Pigs: Ex vivo 1H Magic Angle Spinning NMR Studies BS Somashekar, AG Amin, CD Rithner, JL Troudt, R Basaraba, A Izzo, ... Journal of proteome research 10 (9), 4186-4195, 2011 | 139 | 2011 |
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis SS Gurcha, AR Baulard, L Kremer, C Locht, DB Moody, W Muhlecker, ... Biochemical Journal 365 (2), 441-450, 2002 | 135 | 2002 |