| Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases T Battista, G Colotti, A Ilari, A Fiorillo Molecules 25 (8), 1924, 2020 | 125 | 2020 |
| Identification of chalcone-based antileishmanial agents targeting trypanothione reductase M Ortalli, A Ilari, G Colotti, I De Ionna, T Battista, A Bisi, S Gobbi, A Rampa, ... European journal of medicinal chemistry 152, 527-541, 2018 | 78 | 2018 |
| Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases I Genovese, F Giamogante, L Barazzuol, T Battista, A Fiorillo, M Vicario, ... Cell Death & Disease 11 (10), 861, 2020 | 45 | 2020 |
| Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target T Battista, A Fiorillo, V Chiarini, I Genovese, A Ilari, G Colotti Cancers 12 (4), 887, 2020 | 43 | 2020 |
| Toward a drug against all kinetoplastids: From LeishBox to specific and potent trypanothione reductase inhibitors A Ilari, I Genovese, F Fiorillo, T Battista, I De Ionna, A Fiorillo, G Colotti Molecular Pharmaceutics 15 (8), 3069-3078, 2018 | 36 | 2018 |
| The Met80Ala and Tyr67His/Met80Ala mutants of human cytochrome c shed light on the reciprocal role of Met80 and Tyr67 in regulating ligand access into the heme pocket C Ciaccio, L Tognaccini, T Battista, M Cervelli, BD Howes, R Santucci, ... Journal of Inorganic Biochemistry 169, 86-96, 2017 | 26 | 2017 |
| Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism G Colotti, F Saccoliti, M Gramiccia, T Di Muccio, J Prakash, S Yadav, ... Amino acids 52, 247-259, 2020 | 20 | 2020 |
| Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme L Turcano, T Battista, ET De Haro, A Missineo, C Alli, G Paonessa, ... PLoS Neglected Tropical Diseases 14 (5), e0008339, 2020 | 18 | 2020 |
| Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents I Genovese, A Ilari, T Battista, V Chiarini, F Fazi, A Fiorillo, G Colotti Cancer Drug Resistance, 2018 | 12 | 2018 |
| Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells T Battista, G Pascarella, DS Staid, G Colotti, J Rosati, A Fiorillo, ... International Journal of Molecular Sciences 22 (3), 1293, 2021 | 11 | 2021 |
| Identification and characterization of the pyridoxal 5’-phosphate allosteric site in Escherichia coli pyridoxine 5’-phosphate oxidase A Barile, T Battista, A Fiorillo, ML di Salvo, F Malatesta, A Tramonti, A Ilari, ... Journal of Biological Chemistry 296, 2021 | 11 | 2021 |
| Optimization of potent and specific trypanothione Reductase inhibitors: a structure-based drug discovery approach T Battista, S Federico, S Brogi, L Pozzetti, T Khan, S Butini, A Ramunno, ... ACS Infectious Diseases 8 (8), 1687-1699, 2022 | 8 | 2022 |
| Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome I Genovese, A Carotti, A Ilari, A Fiorillo, T Battista, G Colotti, Y Ivarsson Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (8), 129618, 2020 | 8 | 2020 |
| Investigation of the entry pathway and molecular nature of σ1 receptor ligands G Pascarella, L Antonelli, D Narzi, T Battista, A Fiorillo, G Colotti, ... International Journal of Molecular Sciences 24 (7), 6367, 2023 | 3 | 2023 |
| Structural basis of ubiquitination mediated by protein splicing in early Eukarya V Chiarini, A Fiorillo, S Camerini, M Crescenzi, S Nakamura, T Battista, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (5), 129844, 2021 | 2 | 2021 |
| Identification of small molecule inhibitors of UNC-51-like kinase 1 for cancer treatment MS Semrau, T Battista, V Sidarovich, A Dalle Vedove, R Ortolan, I Manini, ... FEBS OPEN BIO 14, 274-274, 2024 | | 2024 |
| Investigation of the binding mechanism and molecular nature of human Sigma 1 receptor ligands L Antonelli, G Pascarella, D Narzi, T Battista, A Fiorillo, C Exertier, ... FEBS OPEN BIO 14, 100-100, 2024 | | 2024 |
| I12 Deciphering the neuroprotective role of sigma1 receptor, an important function to overcome the symptoms of neurodegenerative disorders G Pascarella, T Battista, G Colotti, J Rosati, A Fiorillo, D Narzi, L Guidoni, ... Journal of Neurology, Neurosurgery and Psychiatry 92 (Suppl 1), A52-A52, 2021 | | 2021 |
| Anti-trypanosomatidal drug discovery: a challenge for structural biology T Battista Università degli Studi di Roma" La Sapienza", 2020 | | 2020 |
