Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles W Stallaert, JF Dorn, E van der Westhuizen, M Audet, M Bouvier PloS one 7 (1), e29420, 2012 | 125 | 2012 |
Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity AM Schönegge, J Gallion, LP Picard, AD Wilkins, C Le Gouill, M Audet, ... Nature communications 8 (1), 2169, 2017 | 92 | 2017 |
Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors W Stallaert, A Christopoulos, M Bouvier Expert opinion on drug discovery 6 (8), 811-825, 2011 | 88 | 2011 |
Purinergic receptor transactivation by the β2-adrenergic receptor increases intracellular Ca2+ in nonexcitable cells W Stallaert, ET Van Der Westhuizen, AM Schönegge, B Plouffe, M Hogue, ... Molecular pharmacology 91 (5), 533-544, 2017 | 77 | 2017 |
The structure of the human cell cycle W Stallaert, KM Kedziora, CD Taylor, TM Zikry, HK Sobon, SR Taylor, ... Cell Systems, 2021 | 67 | 2021 |
Interdependence between EGFR and phosphatases spatially established by vesicular dynamics generates a growth factor sensing and responding network A Stanoev, A Mhamane, KC Schuermann, HE Grecco, W Stallaert, ... Cell systems 7 (3), 295-309. e11, 2018 | 61 | 2018 |
Contact inhibitory Eph signaling suppresses EGF-promoted cell migration by decoupling EGFR activity from vesicular recycling W Stallaert, Y Brüggemann, O Sabet, L Baak, M Gattiglio, PIH Bastiaens Science Signaling 11 (541), eaat0114, 2018 | 58 | 2018 |
The molecular architecture of cell cycle arrest W Stallaert, SR Taylor, KM Kedziora, CD Taylor, HK Sobon, CL Young, ... Molecular Systems Biology 18 (9), e11087, 2022 | 46 | 2022 |
Ligand bias prevents class equality among beta-blockers VJ Thanawala, GS Forkuo, W Stallaert, P Leff, M Bouvier, R Bond Current opinion in pharmacology 16, 50-57, 2014 | 35 | 2014 |
Bistable switches as integrators and actuators during cell cycle progression W Stallaert, KM Kedziora, HX Chao, JE Purvis FEBS letters 593 (20), 2805-2816, 2019 | 31 | 2019 |
Growth factor–dependent ErbB vesicular dynamics couple receptor signaling to spatially and functionally distinct Erk pools Y Brüggemann, LS Karajannis, A Stanoev, W Stallaert, PIH Bastiaens Science Signaling 14 (683), eabd9943, 2021 | 25 | 2021 |
Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2 TP Enrico, W Stallaert, ET Wick, P Ngoi, X Wang, SM Rubin, NG Brown, ... Elife 10, e70691, 2021 | 21 | 2021 |
Cell cycle plasticity underlies fractional resistance to palbociclib in ER+/HER2− breast tumor cells TM Zikry, SC Wolff, JS Ranek, HM Davis, A Naugle, N Luthra, AA Whitman, ... Proceedings of the National Academy of Sciences 121 (7), e2309261121, 2024 | 12 | 2024 |
DELVE: feature selection for preserving biological trajectories in single-cell data JS Ranek, W Stallaert, JJ Milner, M Redick, SC Wolff, AS Beltran, ... Nature Communications 15 (1), 2765, 2024 | 5 | 2024 |
Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations OS Shah, A Nasrazadani, J Foldi, JM Atkinson, CG Kleer, PF McAuliffe, ... Proceedings of the National Academy of Sciences 121 (31), e2322068121, 2024 | 4 | 2024 |
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation A Uboveja, Z Huang, R Buj, A Amalric, H Wang, NK Tangudu, AR Cole, ... bioRxiv, 2024 | 4 | 2024 |
Feature selection for preserving biological trajectories in single-cell data JS Ranek, W Stallaert, J Milner, N Stanley, JE Purvis bioRxiv, 2023 | 2 | 2023 |
Spherical Manifolds Capture Drug-Induced Changes in Tumor Cell Cycle Behavior O Wen, SC Wolff, W Stallaert, D Li, JE Purvis, TM Zikry Biocomputing 2025: Proceedings of the Pacific Symposium, 473-487, 2024 | 1 | 2024 |
Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion AR Cole, R Buj, AT Elhaw, A Uboveja, N Tangudu, S Oesterreich, ... bioRxiv, 2023.12. 02.569652, 2023 | 1 | 2023 |
Contact inhibitory Eph signalling decouples EGFR activity from vesicular recycling to generate contextual plasticity. bioRxiv W Stallaert, O Sabet, Y Bruggemann, L Baak, P Bastiaens | 1 | 2017 |