Anti‐Inflammatory Property of n‐Hexadecanoic Acid: Structural Evidence and Kinetic Assessment V Aparna, KV Dileep, PK Mandal, P Karthe, C Sadasivan, M Haridas Chemical biology & drug design 80 (3), 434-439, 2012 | 949 | 2012 |
Targeting LIF/LIFR signaling in cancer S Viswanadhapalli, KV Dileep, KYJ Zhang, HB Nair, RK Vadlamudi Genes & Diseases 9 (4), 973-980, 2022 | 76 | 2022 |
EC359: a first-in-class small-molecule inhibitor for targeting oncogenic LIFR signaling in triple-negative breast cancer S Viswanadhapalli, Y Luo, GR Sareddy, B Santhamma, M Zhou, M Li, ... Molecular cancer therapeutics 18 (8), 1341-1354, 2019 | 68 | 2019 |
Molecular docking studies of curcumin analogs with phospholipase A2 KV Dileep, I Tintu, C Sadasivan Interdisciplinary Sciences: Computational Life Sciences 3, 189-197, 2011 | 62 | 2011 |
Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery KV Dileep, K Ihara, C Mishima-Tsumagari, M Kukimoto-Niino, ... International Journal of Biological Macromolecules 210, 172-181, 2022 | 57 | 2022 |
Cuminaldehyde as a lipoxygenase inhibitor: in vitro and in silico validation MJ Tomy, KV Dileep, S Prasanth, DS Preethidan, A Sabu, C Sadasivan, ... Applied biochemistry and biotechnology 174, 388-397, 2014 | 51 | 2014 |
Tumor derived extracellular vesicles drive T cell exhaustion in tumor microenvironment through sphingosine mediated signaling and impacting immunotherapy outcomes in ovarian cancer P Gupta, IP Kadamberi, S Mittal, SW Tsaih, J George, S Kumar, ... Advanced Science 9 (14), 2104452, 2022 | 48 | 2022 |
A comprehensive approach to ascertain the binding mode of curcumin with DNA P Haris, V Mary, P Aparna, KV Dileep, C Sudarsanakumar Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 175, 155-163, 2017 | 45 | 2017 |
Design of potent inhibitors of acetylcholinesterase using morin as the starting compound C Remya, KV Dileep, I Tintu, EJ Variyar, C Sadasivan Frontiers in Life Science 6 (3-4), 107-117, 2012 | 43 | 2012 |
Inhibition of Beta-Lactamase by 1,4-Naphthalenedione from the Plant Holoptelea integrifolia NV Vinod, R Shijina, KV Dileep, C Sadasivan Applied biochemistry and biotechnology 160, 1752-1759, 2010 | 38 | 2010 |
Human glutaminyl cyclase: Structure, function, inhibitors and involvement in Alzheimer’s disease DK Vijayan, KYJ Zhang Pharmacological research 147, 104342, 2019 | 35 | 2019 |
Functionalised dihydroazo pyrimidine derivatives from Morita–Baylis–Hillman acetates: synthesis and studies against acetylcholinesterase as its inhibitors EK Reddy, C Remya, AM Sajith, KV Dileep, C Sadasivan, S Anwar RSC advances 6 (81), 77431-77439, 2016 | 35 | 2016 |
Flavanone glycosides as acetylcholinesterase inhibitors: computational and experimental evidence C Remya, KV Dileep, I Tintu, EJ Variyar, C Sadasivan Indian journal of pharmaceutical sciences 76 (6), 567, 2014 | 34 | 2014 |
Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase–design, synthesis and biological evaluation C Remya, KV Dileep, EK Reddy, K Mantosh, K Lakshmi, RS Jacob, ... Computational and Structural Biotechnology Journal 19, 4517-4537, 2021 | 28 | 2021 |
Amyloid beta hypothesis in Alzheimer's disease: major culprits and recent therapeutic strategies D Vijayan, R Chandra Current drug targets 21 (2), 148-166, 2020 | 28 | 2020 |
Derivatives Form Better Lipoxygenase Inhibitors than Piperine: In Vitro and In Silico Study MJ Tomy, CS Sharanya, KV Dileep, S Prasanth, A Sabu, C Sadasivan, ... Chemical Biology & Drug Design 85 (6), 715-721, 2015 | 28 | 2015 |
Gossypin as a novel selective dual inhibitor of V-RAF murine sarcoma viral oncogene homolog B1 and cyclin-dependent kinase 4 for melanoma S Bhaskaran, KV Dileep, SS Deepa, C Sadasivan, M Klausner, ... Molecular cancer therapeutics 12 (4), 361-372, 2013 | 27 | 2013 |
An isoquinoline alkaloid, berberine, can inhibit fungal alpha amylase: enzyme kinetic and molecular modeling studies I Tintu, KV Dileep, A Augustine, C Sadasivan Chemical Biology & Drug Design 80 (4), 554-560, 2012 | 26 | 2012 |
In vitro inhibitory profile of NDGA against AChE and its in silico structural modifications based on ADME profile C Remya, KV Dileep, I Tintu, EJ Variyar, C Sadasivan Journal of molecular modeling 19, 1179-1194, 2013 | 24 | 2013 |
Comparative studies on the inhibitory activities of selected benzoic acid derivatives against secretory phospholipase A 2, a key enzyme involved in the inflammatory pathway KV Dileep, C Remya, J Cerezo, A Fassihi, H Pérez-Sánchez, ... Molecular BioSystems 11 (7), 1973-1979, 2015 | 23 | 2015 |