Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease J Leffler, M Martin, B Gullstrand, H Tydén, C Lood, L Truedsson, ... The Journal of Immunology 188 (7), 3522-3531, 2012 | 577 | 2012 |
The complement system in systemic lupus erythematosus: an update J Leffler, AA Bengtsson, AM Blom Annals of the rheumatic diseases 73 (9), 1601-1606, 2014 | 323 | 2014 |
Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus J Leffler, B Gullstrand, A Jönsen, JÅ Nilsson, M Martin, AM Blom, ... Arthritis research & therapy 15, 1-9, 2013 | 148 | 2013 |
Annexin A2 and A5 serve as new ligands for C1q on apoptotic cells M Martin, J Leffler, AM Blom Journal of Biological Chemistry 287 (40), 33733-33744, 2012 | 136 | 2012 |
Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes M Martin, J Leffler, KI Smoląg, J Mytych, A Björk, LD Chaves, JJ Alexander, ... Cell Death & Differentiation 23 (5), 903-911, 2016 | 108 | 2016 |
Degradation of neutrophil extracellular traps is decreased in patients with antiphospholipid syndrome J Leffler, L Stojanovich, Y Shoenfeld, G Bogdanovic, R Hesselstrand, ... Clin Exp Rheumatol 32 (1), 66-70, 2014 | 97 | 2014 |
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells J Leffler, AP Herbert, E Norström, CQ Schmidt, PN Barlow, AM Blom, ... Journal of Biological Chemistry 285 (6), 3766-3776, 2010 | 90 | 2010 |
A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources J Leffler, K Ciacma, B Gullstrand, AA Bengtsson, M Martin, AM Blom Arthritis Research & Therapy 17, 1-10, 2015 | 61 | 2015 |
Immunological processes driving IgE sensitisation and disease development in males and females J Leffler, PA Stumbles, DH Strickland International Journal of Molecular Sciences 19 (6), 1554, 2018 | 58 | 2018 |
Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis S Trend, J Leffler, AP Jones, L Cha, S Gorman, DA Brown, SN Breit, ... Scientific Reports 11 (1), 5244, 2021 | 57 | 2021 |
Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus M Martin, KI Smoląg, A Björk, B Gullstrand, M Okrój, J Leffler, A Jönsen, ... Arthritis research & therapy 19, 1-9, 2017 | 51 | 2017 |
Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation KT Mincham, NM Scott, JF Lauzon-Joset, J Leffler, AN Larcombe, ... The Journal of clinical investigation 128 (11), 4856-4869, 2018 | 42 | 2018 |
Protection against maternal infection-associated fetal growth restriction: proof-of-concept with a microbial-derived immunomodulator NM Scott, JF Lauzon-Joset, AC Jones, KT Mincham, NM Troy, J Leffler, ... Mucosal immunology 10 (3), 789-801, 2017 | 39 | 2017 |
Factor H autoantibodies in patients with antiphospholipid syndrome and thrombosis AF Zadura, AA Memon, L Stojanovich, C Perricone, F Conti, G Valesini, ... The Journal of rheumatology 42 (10), 1786-1793, 2015 | 38 | 2015 |
Decreased neutrophil extracellular trap degradation in Shiga toxin-associated haemolytic uraemic syndrome J Leffler, Z Prohászka, B Mikes, G Sinkovits, K Ciacma, P Farkas, M Réti, ... Journal of innate immunity 9 (1), 12-21, 2017 | 32 | 2017 |
Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school‐aged children J Leffler, JF Read, AC Jones, D Mok, EM Hollams, IA Laing, PN Le Souef, ... Pediatric Allergy and Immunology 30 (6), 646-653, 2019 | 23 | 2019 |
Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations J Leffler, AC Jones, EM Hollams, F Prastanti, PN Le Souëf, PG Holt, ... Journal of Allergy and Clinical Immunology 142 (5), 1639-1641. e5, 2018 | 21 | 2018 |
Oestrogen amplifies pre‐existing atopy‐associated Th2 bias in an experimental asthma model JF Lauzon‐Joset, KT Mincham, AP Abad, BP Short, PG Holt, ... Clinical & Experimental Allergy 50 (3), 391-400, 2020 | 20 | 2020 |
Sex-specific environmental impacts on initiation and progression of multiple sclerosis J Leffler, S Trend, S Gorman, PH Hart Frontiers in Neurology 13, 835162, 2022 | 17 | 2022 |
Potential immunological effects of gender-affirming hormone therapy in transgender people–an unexplored area of research AA White, A Lin, X Bickendorf, BS Cavve, JK Moore, A Siafarikas, ... Therapeutic Advances in Endocrinology and Metabolism 13, 20420188221139612, 2022 | 15 | 2022 |