Theo dõi
Charles Gersbach
Charles Gersbach
Professor of Biomedical Engineering, Duke University
Email được xác minh tại duke.edu - Trang chủ
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
T Gaj, CA Gersbach, CF Barbas
Trends in biotechnology 31 (7), 397-405, 2013
50162013
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
IB Hilton, AM D'ippolito, CM Vockley, PI Thakore, GE Crawford, TE Reddy, ...
Nature biotechnology 33 (5), 510-517, 2015
22222015
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, ...
Nature methods 10 (10), 973-976, 2013
17332013
The next generation of CRISPR–Cas technologies and applications
A Pickar-Oliver, CA Gersbach
Nature reviews Molecular cell biology 20 (8), 490-507, 2019
14472019
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ...
Science 351 (6271), 403-407, 2016
13842016
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
PI Thakore, AM D'ippolito, L Song, A Safi, NK Shivakumar, AM Kabadi, ...
Nature methods 12 (12), 1143-1149, 2015
10702015
Genome-editing technologies for gene and cell therapy
ML Maeder, CA Gersbach
Molecular therapy 24 (3), 430-446, 2016
8472016
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation
LR Polstein, CA Gersbach
Nature chemical biology 11 (3), 198-200, 2015
7302015
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy
DG Ousterout, AM Kabadi, PI Thakore, WH Majoros, TE Reddy, ...
Nature communications 6 (1), 6244, 2015
5552015
Editing the epigenome: technologies for programmable transcription and epigenetic modulation
PI Thakore, JB Black, IB Hilton, CA Gersbach
Nature methods 13 (2), 127-137, 2016
5292016
CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome
TS Klann, JB Black, M Chellappan, A Safi, L Song, IB Hilton, GE Crawford, ...
Nature biotechnology 35 (6), 561-568, 2017
4902017
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
AM Kabadi, DG Ousterout, IB Hilton, CA Gersbach
Nucleic acids research 42 (19), e147-e147, 2014
4632014
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, ...
Nature medicine 25 (3), 427-432, 2019
4312019
Increasing the specificity of CRISPR systems with engineered RNA secondary structures
DD Kocak, EA Josephs, V Bhandarkar, SS Adkar, JB Kwon, CA Gersbach
Nature biotechnology 37 (6), 657-666, 2019
3542019
Synergistic and tunable human gene activation by combinations of synthetic transcription factors
P Perez-Pinera, DG Ousterout, JM Brunger, AM Farin, KA Glass, F Guilak, ...
Nature methods 10 (3), 239-242, 2013
3402013
The once and future gene therapy
K Bulaklak, CA Gersbach
Nature communications 11 (1), 1-4, 2020
3062020
How vinculin regulates force transmission
DW Dumbauld, TT Lee, A Singh, J Scrimgeour, CA Gersbach, EA Zamir, ...
Proceedings of the National Academy of Sciences 110 (24), 9788-9793, 2013
3002013
Advances in targeted genome editing
P Perez-Pinera, DG Ousterout, CA Gersbach
Current opinion in chemical biology 16 (3-4), 268-277, 2012
2602012
Targeted epigenetic remodeling of endogenous loci by CRISPR/Cas9-based transcriptional activators directly converts fibroblasts to neuronal cells
JB Black, AF Adler, HG Wang, AM D’Ippolito, HA Hutchinson, TE Reddy, ...
Cell stem cell 19 (3), 406-414, 2016
2512016
A CRISPR/Cas9-based system for reprogramming cell lineage specification
S Chakraborty, HY Ji, AM Kabadi, CA Gersbach, N Christoforou, ...
Stem cell reports 3 (6), 940-947, 2014
2432014
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