Theo dõi
Dirk Grimm
Dirk Grimm
Heidelberg University Hospital
Email được xác minh tại bioquant.uni-heidelberg.de - Trang chủ
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
D Grimm, KL Streetz, CL Jopling, TA Storm, K Pandey, CR Davis, ...
Nature 441 (7092), 537-541, 2006
21592006
Novel tools for production and purification of recombinant adenoassociated virus vectors
D Grimm, A Kern, K Rittner, JA Kleinschmidt
Human gene therapy 9 (18), 2745-2760, 1998
9061998
In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses
D Grimm, JS Lee, L Wang, T Desai, B Akache, TA Storm, MA Kay
Journal of virology 82 (12), 5887-5911, 2008
8692008
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
B Akache, D Grimm, K Pandey, SR Yant, H Xu, MA Kay
Journal of virology 80 (19), 9831-9836, 2006
5742006
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
Y Malato, S Naqvi, N Schürmann, R Ng, B Wang, J Zape, MA Kay, ...
The Journal of clinical investigation 121 (12), 4850-4860, 2011
5272011
DNA helicase‐mediated packaging of adeno‐associated virus type 2 genomes into preformed capsids
JA King, R Dubielzig, D Grimm, JA Kleinschmidt
The EMBO journal, 2001
4642001
From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy
D Grimm, MA Kay
Current gene therapy 3 (4), 281-304, 2003
4612003
Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6
D Grimm, MA Kay, JA Kleinschmidt
Molecular Therapy 7 (6), 839-850, 2003
4202003
Loss of epigenetic information as a cause of mammalian aging
JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ...
Cell 186 (2), 305-326. e27, 2023
4192023
CRISPR/Cas9‐mediated genome engineering: an adeno‐associated viral (AAV) vector toolbox
E Senís, C Fatouros, S Große, E Wiedtke, D Niopek, AK Mueller, K Börner, ...
Biotechnology journal 9 (11), 1402-1412, 2014
3532014
Subcellular compartmentalization of adeno-associated virus type 2 assembly
A Wistuba, A Kern, S Weger, D Grimm, JA Kleinschmidt
Journal of virology 71 (2), 1341-1352, 1997
3131997
Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems
P Parameswaran, E Sklan, C Wilkins, T Burgon, MA Samuel, R Lu, ...
PLoS pathogens 6 (2), e1000764, 2010
3102010
Macrophage microRNA-155 promotes cardiac hypertrophy and failure
S Heymans, MF Corsten, W Verhesen, P Carai, REW Van Leeuwen, ...
Circulation 128 (13), 1420-1432, 2013
2912013
Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments
S Fanucchi, ET Fok, E Dalla, Y Shibayama, K Börner, EY Chang, ...
Nature genetics 51 (1), 138-150, 2019
2812019
Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic
JC Giering, D Grimm, TA Storm, MA Kay
Molecular therapy 16 (9), 1630-1636, 2008
2812008
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy
L Amoasii, C Long, H Li, AA Mireault, JM Shelton, E Sanchez-Ortiz, ...
Science translational medicine 9 (418), eaan8081, 2017
2712017
Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver
D Grimm, L Wang, JS Lee, N Schürmann, S Gu, K Börner, TA Storm, ...
The Journal of clinical investigation 120 (9), 3106-3119, 2010
2642010
Progress in adeno-associated virus type 2 vector production: promises and prospects for clinical use
D Grimm, JA Kleinschmidt
Human gene therapy 10 (15), 2445-2450, 1999
2601999
Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?
D Grimm, MA Kay
The Journal of clinical investigation 117 (12), 3633-3641, 2007
2592007
Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy
D Grimm, S Zhou, H Nakai, CE Thomas, TA Storm, S Fuess, T Matsushita, ...
Blood 102 (7), 2412-2419, 2003
2572003
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