Theo dõi
Humaira Gowher
Humaira Gowher
Associate Professor, Department of Biochemistry, Purdue University
Email được xác minh tại purdue.edu
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Biochemistry and biology of mammalian DNA methyltransferases
A Hermann, H Gowher, A Jeltsch
Cellular and Molecular Life Sciences CMLS 61, 2571-2587, 2004
8122004
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
H Gowher, K Liebert, A Hermann, G Xu, A Jeltsch
Journal of Biological Chemistry 280 (14), 13341-13348, 2005
4212005
Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA
M Fatemi, A Hermann, H Gowher, A Jeltsch
European journal of biochemistry 269 (20), 4981-4984, 2002
3462002
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpA sites
H Gowher, A Jeltsch
Journal of molecular biology 309 (5), 1201-1208, 2001
3172001
Chromatin targeting of de novo DNA methyltransferases by the PWWP domain
YZ Ge, MT Pu, H Gowher, HP Wu, JP Ding, A Jeltsch, GL Xu
Journal of Biological Chemistry 279 (24), 25447-25454, 2004
2722004
DNA of Drosophila melanogaster contains 5‐methylcytosine
H Gowher, O Leismann, A Jeltsch
The EMBO journal, 2000
2652000
Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases
H Gowher, A Jeltsch
Journal of Biological Chemistry 277 (23), 20409-20414, 2002
2642002
Mammalian DNA methyltransferases: new discoveries and open questions
H Gowher, A Jeltsch
Biochemical Society Transactions 46 (5), 1191-1202, 2018
1702018
DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
N Veland, Y Lu, S Hardikar, S Gaddis, Y Zeng, B Liu, MR Estecio, ...
Nucleic acids research 47 (1), 152-167, 2019
1472019
VEZF1 elements mediate protection from DNA methylation
J Dickson, H Gowher, R Strogantsev, M Gaszner, A Hair, G Felsenfeld, ...
PLoS genetics 6 (1), e1000804, 2010
1372010
The Escherichia coli dam DNA methyltransferase modifies DNA in a highly processive reaction
S Urig, H Gowher, A Hermann, C Beck, M Fatemi, A Humeny, A Jeltsch
Journal of molecular biology 319 (5), 1085-1096, 2002
1332002
Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy
H Gowher, A Jeltsch
Cancer biology & therapy 3 (11), 1062-1068, 2004
1262004
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase
H Gowher, P Loutchanwoot, O Vorobjeva, V Handa, RZ Jurkowska, ...
Journal of molecular biology 357 (3), 928-941, 2006
1242006
Chromatin domains, insulators, and the regulation of gene expression
R Ghirlando, K Giles, H Gowher, T Xiao, Z Xu, H Yao, G Felsenfeld
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (7), 644-651, 2012
1182012
De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases
H Gowher, CJ Stockdale, R Goyal, H Ferreira, T Owen-Hughes, A Jeltsch
Biochemistry 44 (29), 9899-9904, 2005
1032005
Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme
S Reither, F Li, H Gowher, A Jeltsch
Journal of molecular biology 329 (4), 675-684, 2003
842003
Molecular enzymology of the Eco RV DNA-(adenine-N6)-methyltransferase: kinetics of DNA binding and bending, kinetic mechanism and linear diffusion of the enzyme on DNA
H Gowher, A Jeltsch
Journal of molecular biology 303 (1), 93-110, 2000
832000
An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation
CJ Petell, L Alabdi, M He, P San Miguel, R Rose, H Gowher
Nucleic acids research 44 (16), 7605-7617, 2016
742016
Chromatin boundaries, insulators, and long-range interactions in the nucleus
KE Giles, H Gowher, R Ghirlando, C Jin, G Felsenfeld
Cold Spring Harbor symposia on quantitative biology 75, 79-85, 2010
692010
Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L
ZH Xie, YN Huang, ZX Chen, AD Riggs, JP Ding, H Gowher, A Jeltsch, ...
Human molecular genetics 15 (9), 1375-1385, 2006
682006
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