| Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility JK Gjerstad, SL Lightman, F Spiga Stress 21 (5), 403-416, 2018 | 533 | 2018 |
| Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis P Domingo, I Mur, GM Mateo, M del Mar Gutierrez, V Pomar, N de Benito, ... Jama 326 (6), 499-518, 2021 | 532 | 2021 |
| HPA axis‐rhythms F Spiga, JJ Walker, JR Terry, SL Lightman Comprehensive physiology 4 (3), 1273-1298, 2011 | 378 | 2011 |
| The significance of glucocorticoid pulsatility SL Lightman, CC Wiles, HC Atkinson, DE Henley, GM Russell, ... European journal of pharmacology 583 (2-3), 255-262, 2008 | 309 | 2008 |
| Differential effects of exposure to low-light or high-light open-field on anxiety-related behaviors: relationship to c-Fos expression in serotonergic and non-serotonergic … JA Bouwknecht, F Spiga, DR Staub, MW Hale, A Shekhar, CA Lowry Brain research bulletin 72 (1), 32-43, 2007 | 220 | 2007 |
| The origin of glucocorticoid hormone oscillations JJ Walker, F Spiga, E Waite, Z Zhao, Y Kershaw, JR Terry, SL Lightman PLoS biology 10 (6), e1001341, 2012 | 199 | 2012 |
| Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat ML Barbaccia, D Affricano, RH Purdy, E Maciocco, F Spiga, G Biggio Neuropsychopharmacology 25 (4), 489-497, 2001 | 123 | 2001 |
| ACTH-dependent ultradian rhythm of corticosterone secretion F Spiga, EJ Waite, Y Liu, YM Kershaw, G Aguilera, SL Lightman Endocrinology 152 (4), 1448-1457, 2011 | 111 | 2011 |
| Exposure to high-and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex MW Hale, JA Bouwknecht, F Spiga, A Shekhar, CA Lowry Brain research bulletin 71 (1-3), 174-182, 2006 | 102 | 2006 |
| Dynamic pituitary-adrenal interactions in response to cardiac surgery B Gibbison, F Spiga, JJ Walker, GM Russell, K Stevenson, Y Kershaw, ... Critical care medicine 43 (4), 791-800, 2015 | 99 | 2015 |
| Urocortin 2 increases c-Fos expression in topographically organized subpopulations of serotonergic neurons in the rat dorsal raphe nucleus DR Staub, F Spiga, CA Lowry Brain research 1044 (2), 176-189, 2005 | 98 | 2005 |
| Injections of urocortin 1 into the basolateral amygdala induce anxiety-like behavior and c-Fos expression in brainstem serotonergic neurons F Spiga, SL Lightman, A Shekhar, CA Lowry Neuroscience 138 (4), 1265-1276, 2006 | 97 | 2006 |
| Mathematical modelling of endocrine systems E Zavala, KCA Wedgwood, M Voliotis, J Tabak, F Spiga, SL Lightman, ... Trends in Endocrinology & Metabolism 30 (4), 244-257, 2019 | 86 | 2019 |
| Rapid intra-adrenal feedback regulation of glucocorticoid synthesis JJ Walker, F Spiga, R Gupta, Z Zhao, SL Lightman, JR Terry Journal of the Royal Society Interface 12 (102), 20140875, 2015 | 86 | 2015 |
| Dynamics of adrenal glucocorticoid steroidogenesis in health and disease F Spiga, SL Lightman Molecular and cellular endocrinology 408, 227-234, 2015 | 75 | 2015 |
| Opposite effects of short-versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain M Serra, GM Pisu, M Muggironi, V Parodo, G Papi, R Sari, L Dazzi, ... Psychopharmacology 158, 48-54, 2001 | 73 | 2001 |
| WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group. Association between administration of IL-6 antagonists and mortality among patients hospitalized for … M Shankar-Hari, CL Vale, PJ Godolphin, D Fisher, JPT Higgins, F Spiga, ... jama 326 (6), 499-518, 2021 | 71 | 2021 |
| Dynamic responses of the adrenal steroidogenic regulatory network F Spiga, E Zavala, JJ Walker, Z Zhao, JR Terry, SL Lightman Proceedings of the National Academy of Sciences 114 (31), E6466-E6474, 2017 | 70 | 2017 |
| Effect of the glucocorticoid receptor antagonist Org 34850 on basal and stress‐induced corticosterone secretion F Spiga, LR Harrison, SA Wood, HC Atkinson, CP MacSweeney, ... Journal of neuroendocrinology 19 (11), 891-900, 2007 | 70 | 2007 |
| Constant light disrupts the circadian rhythm of steroidogenic proteins in the rat adrenal gland SY Park, JJ Walker, NW Johnson, Z Zhao, SL Lightman, F Spiga Molecular and cellular endocrinology 371 (1-2), 114-123, 2013 | 68 | 2013 |
