Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl-and asymmetric dimethyl-arginine residues on histone H4 TM Lakowski, A Frankel Biochemical Journal 421 (2), 253-261, 2009 | 152 | 2009 |
A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism TM Lakowski, A Frankel Journal of Biological Chemistry 283 (15), 10015-10025, 2008 | 105 | 2008 |
Deep graph embedding for prioritizing synergistic anticancer drug combinations P Jiang, S Huang, Z Fu, Z Sun, TM Lakowski, P Hu Computational and structural biotechnology journal 18, 427-438, 2020 | 103 | 2020 |
Transcriptional regulation of brain-derived neurotrophic factor (BDNF) by methyl CpG binding protein 2 (MeCP2): a novel mechanism for re-myelination and/or myelin repair … T KhorshidAhmad, C Acosta, C Cortes, TM Lakowski, S Gangadaran, ... Molecular neurobiology 53, 1092-1107, 2016 | 83 | 2016 |
Physiologic changes in the heart following cessation of mechanical ventilation in a porcine model of donation after circulatory death: implications for cardiac transplantation CW White, R Lillico, J Sandha, D Hasanally, F Wang, E Ambrose, A Müller, ... American Journal of Transplantation 16 (3), 783-793, 2016 | 80 | 2016 |
A Protein Arginine N-Methyltransferase 1 (PRMT1) and 2 Heteromeric Interaction Increases PRMT1 Enzymatic Activity ML Pak, TM Lakowski, D Thomas, MI Vhuiyan, K Hüsecken, A Frankel Biochemistry 50 (38), 8226-8240, 2011 | 65 | 2011 |
Calcium‐induced folding of a fragment of calmodulin composed of EF‐hands 2 and 3 TM Lakowski, GM Lee, M Okon, RE Reid, LP McIntosh Protein science 16 (6), 1119-1132, 2007 | 51 | 2007 |
SARS‐CoV‐2 multifaceted interaction with the human host. Part II: Innate immunity response, immunopathology, and epigenetics TH Beacon, RC Su, TM Lakowski, GP Delcuve, JR Davie IUBMB life 72 (11), 2331-2354, 2020 | 48 | 2020 |
Nη-Substituted Arginyl Peptide Inhibitors of Protein Arginine N-Methyltransferases TM Lakowski, P ’t Hart, CA Ahern, NI Martin, A Frankel ACS chemical biology 5 (11), 1053-1063, 2010 | 44 | 2010 |
PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X MI Vhuiyan, ML Pak, MA Park, D Thomas, TM Lakowski, CE Chalfant, ... The journal of biochemistry 162 (1), 17-25, 2017 | 39 | 2017 |
Förster resonance energy transfer measurements of cofactor‐dependent effects on protein arginine N‐methyltransferase homodimerization D Thomas, TM Lakowski, ML Pak, JJ Kim, A Frankel Protein Science 19 (11), 2141-2151, 2010 | 35 | 2010 |
HDAC inhibitors induce global changes in histone lysine and arginine methylation and alter expression of lysine demethylases R Lillico, MG Sobral, N Stesco, TM Lakowski Journal of proteomics 133, 125-133, 2016 | 33 | 2016 |
Approaches to measuring the activities of protein arginine N-methyltransferases TM Lakowski, C Zurita-Lopez, SG Clarke, A Frankel Analytical biochemistry 397 (1), 1, 2009 | 33 | 2009 |
Disposition, metabolism and histone deacetylase and acetyltransferase inhibition activity of tetrahydrocurcumin and other curcuminoids JT Novaes, R Lillico, CL Sayre, K Nagabhushanam, M Majeed, Y Chen, ... Pharmaceutics 9 (4), 45, 2017 | 31 | 2017 |
Selective DOT1L, LSD1, and HDAC class I inhibitors reduce HOXA9 expression in MLL-AF9 rearranged leukemia cells, but dysregulate the expression of many histone-modifying enzymes R Lillico, CK Lawrence, TM Lakowski Journal of proteome research 17 (8), 2657-2667, 2018 | 30 | 2018 |
Peptidic Partial Bisubstrates as Inhibitors of the Protein Arginine N‐Methyltransferases P 't Hart, TM Lakowski, D Thomas, A Frankel, NI Martin ChemBioChem 12 (9), 1427-1432, 2011 | 28 | 2011 |
MS3 fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM3 TM Lakowski, A Szeitz, ML Pak, D Thomas, MI Vhuiyan, J Kotthaus, ... Journal of proteomics 80, 43-54, 2013 | 24 | 2013 |
Absolute oral bioavailability of creatine monohydrate in rats: debunking a myth EA Alraddadi, R Lillico, JL Vennerstrom, TM Lakowski, DW Miller Pharmaceutics 10 (1), 31, 2018 | 23 | 2018 |
Antimicrobial prophylaxis for patients undergoing cardiac surgery: intraoperative cefazolin concentrations and sternal wound infections SA Zelenitsky, D Calic, RC Arora, HP Grocott, TM Lakowski, R Lillico, ... Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01360-18, 2018 | 22 | 2018 |
Predicting breast cancer drug response using a multiple-layer cell line drug response network model S Huang, P Hu, TM Lakowski BMC cancer 21 (1), 648, 2021 | 19 | 2021 |