| An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure KS Thorneloe, M Cheung, W Bao, H Alsaid, S Lenhard, MY Jian, ... Science translational medicine 4 (159), 159ra148-159ra148, 2012 | 353 | 2012 |
| Osteoarthritis Year in Review 2016: biomarkers (biochemical markers) A Mobasheri, AC Bay-Jensen, WE Van Spil, J Larkin, MC Levesque Osteoarthritis and cartilage 25 (2), 199-208, 2017 | 196 | 2017 |
| Direct Activation of Protein Kinase C by 1α, 25-Dihydroxyvitamin D3 (∗) SJ Slater, MB Kelly, FJ Taddeo, JD Larkin, MD Yeager, JA McLane, C Ho, ... Journal of Biological Chemistry 270 (12), 6639-6643, 1995 | 160 | 1995 |
| Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT) H Deng, H O’Keefe, CP Davie, KE Lind, RA Acharya, GJ Franklin, J Larkin, ... Journal of medicinal chemistry 55 (16), 7061-7079, 2012 | 159 | 2012 |
| Protein Kinase Cα Contains Two Activator Binding Sites That Bind Phorbol Esters and Diacylglycerols with Opposite Affinities (∗) SJ Slater, C Ho, MB Kelly, JD Larkin, FJ Taddeo, MD Yeager, CD Stubbs Journal of Biological Chemistry 271 (9), 4627-4631, 1996 | 154 | 1996 |
| Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification J Larkin, TA Lohr, L Elefante, J Shearin, R Matico, JL Su, Y Xue, F Liu, ... Osteoarthritis and cartilage 23 (8), 1254-1266, 2015 | 133 | 2015 |
| Hepatitis B virus transgenic mouse model of chronic liver disease J Larkin, M Clayton, B Sun, CE Perchonock, JL Morgan, LD Siracusa, ... Nature medicine 5 (8), 907-912, 1999 | 108 | 1999 |
| Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical phenotypes and … A Mobasheri, WE van Spil, E Budd, I Uzieliene, E Bernotiene, ... Current opinion in rheumatology 31 (1), 80-89, 2019 | 106 | 2019 |
| Osteoarthritis endotype discovery via clustering of biochemical marker data F Angelini, P Widera, A Mobasheri, J Blair, A Struglics, M Uebelhoer, ... Annals of the rheumatic diseases 81 (5), 666-675, 2022 | 94 | 2022 |
| Synergistic antiviral activity of human interferon combinations in the hepatitis C virus replicon system J Larkin, L Jin, M Farmen, D Venable, Y Huang, SL Tan, JI Glass Journal of interferon & cytokine research 23 (5), 247-257, 2003 | 94 | 2003 |
| Interaction of alcohols and anesthetics with protein kinase Cα SJ Slater, MB Kelly, JD Larkin, C Ho, A Mazurek, FJ Taddeo, MD Yeager, ... Journal of Biological Chemistry 272 (10), 6167-6173, 1997 | 91 | 1997 |
| Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis RE Miller, PB Tran, S Ishihara, J Larkin, AM Malfait Osteoarthritis and cartilage 24 (2), 299-306, 2016 | 83 | 2016 |
| Chronic ethanol consumption stimulates hepatitis B virus gene expression and replication in transgenic mice J Larkin, MM Clayton, J Liu, MA Feitelson Hepatology 34 (4), 792-797, 2001 | 80 | 2001 |
| Determinants of versican-V1 proteoglycan processing by the metalloproteinase ADAMTS5 SJ Foulcer, CM Nelson, MV Quintero, B Kuberan, J Larkin, ... Journal of Biological Chemistry 289 (40), 27859-27873, 2014 | 69 | 2014 |
| New animal models of hepatitis B and C MA Feitelson, JD Larkin ILAR journal 42 (2), 127-138, 2001 | 69 | 2001 |
| Multi-classifier prediction of knee osteoarthritis progression from incomplete imbalanced longitudinal data P Widera, PMJ Welsing, C Ladel, J Loughlin, FPFJ Lafeber, F Petit Dop, ... Scientific Reports 10 (1), 8427, 2020 | 68 | 2020 |
| Polyunsaturation in cell membranes and lipid bilayers and its effects on membrane proteins SJ Slater, MB Kelly, MD Yeager, J Larkin, C Ho, CD Stubbs Lipids 31, S189-S192, 1996 | 63 | 1996 |
| Cohort profile: The Applied Public-Private Research enabling OsteoArthritis Clinical Headway (IMI-APPROACH) study: a 2-year, European, cohort study to describe, validate and … EM van Helvoort, WE van Spil, MP Jansen, PMJ Welsing, M Kloppenburg, ... BMJ open 10 (7), e035101, 2020 | 60 | 2020 |
| Cytokine-activated natural killer cells exert direct killing of hepatoma cells harboring hepatitis C virus replicons J Larkin, A Bost, JI Glass, SL Tan Journal of interferon & cytokine research 26 (12), 854-865, 2006 | 51 | 2006 |
| CD44 differentially activates mouse NK T cells and conventional T cells J Larkin, GJ Renukaradhya, V Sriram, W Du, J Gervay-Hague, ... The Journal of Immunology 177 (1), 268-279, 2006 | 51 | 2006 |
