| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 13897* | 2016 |
| Neuroinflammation in Alzheimer's disease MT Heneka, MJ Carson, J El Khoury, GE Landreth, F Brosseron, ... The Lancet Neurology 14 (4), 388-405, 2015 | 5996 | 2015 |
| Onset and progression in inherited ALS determined by motor neurons and microglia S Boillée, K Yamanaka, CS Lobsiger, NG Copeland, NA Jenkins, ... Science 312 (5778), 1389-1392, 2006 | 1958 | 2006 |
| Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis K Yamanaka, SJ Chun, S Boillee, N Fujimori-Tonou, H Yamashita, ... Nature neuroscience 11 (3), 251-253, 2008 | 1345 | 2008 |
| Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex K Iwai, K Yamanaka, T Kamura, N Minato, RC Conaway, JW Conaway, ... Proceedings of the National Academy of Sciences 96 (22), 12436-12441, 1999 | 640 | 1999 |
| Antisense oligonucleotide therapy for neurodegenerative disease RA Smith, TM Miller, K Yamanaka, BP Monia, TP Condon, G Hung, ... The Journal of clinical investigation 116 (8), 2290-2296, 2006 | 635 | 2006 |
| NEDD8 recruits E2‐ubiquitin to SCF E3 ligase T Kawakami, T Chiba, T Suzuki, K Iwai, K Yamanaka, N Minato, H Suzuki, ... The EMBO journal, 2001 | 413 | 2001 |
| Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice K Yamanaka, S Boillee, EA Roberts, ML Garcia, M McAlonis-Downes, ... Proceedings of the National Academy of Sciences 105 (21), 7594-7599, 2008 | 382 | 2008 |
| Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS A Israelson, N Arbel, S Da Cruz, H Ilieva, K Yamanaka, ... Neuron 67 (4), 575-587, 2010 | 357 | 2010 |
| A Seeding Reaction Recapitulates Intracellular Formation of Sarkosyl-insoluble Transactivation Response Element (TAR) DNA-binding Protein-43 Inclusions*♦ Y Furukawa, K Kaneko, S Watanabe, K Yamanaka, N Nukina Journal of Biological Chemistry 286 (21), 18664-18672, 2011 | 283 | 2011 |
| Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis Y Furukawa, K Kaneko, K Yamanaka, TV O'Halloran, N Nukina Journal of Biological Chemistry 283 (35), 24167-24176, 2008 | 252 | 2008 |
| Loss of TDP-43 causes age-dependent progressive motor neuron degeneration Y Iguchi, M Katsuno, J Niwa, S Takagi, S Ishigaki, K Ikenaka, K Kawai, ... Brain 136 (5), 1371-1382, 2013 | 243 | 2013 |
| Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS S Watanabe, H Ilieva, H Tamada, H Nomura, O Komine, F Endo, S Jin, ... EMBO molecular medicine 8 (12), 1421-1437, 2016 | 239 | 2016 |
| The multi-dimensional roles of astrocytes in ALS K Yamanaka, O Komine Neuroscience research 126, 31-38, 2018 | 235 | 2018 |
| Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2 K Yamanaka, H Ishikawa, Y Megumi, F Tokunaga, M Kanie, TA Rouault, ... Nature cell biology 5 (4), 336-340, 2003 | 232 | 2003 |
| Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells F Endo, O Komine, N Fujimori-Tonou, M Katsuno, S Jin, S Watanabe, ... Cell reports 11 (4), 592-604, 2015 | 231 | 2015 |
| Spliceosome integrity is defective in the motor neuron diseases ALS and SMA H Tsuiji, Y Iguchi, A Furuya, A Kataoka, H Hatsuta, N Atsuta, F Tanaka, ... EMBO molecular medicine 5 (2), 221-234, 2013 | 224 | 2013 |
| Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice CS Lobsiger, S Boillee, M McAlonis-Downes, AM Khan, ML Feltri, ... Proceedings of the National Academy of Sciences 106 (11), 4465-4470, 2009 | 219 | 2009 |
| Ubiquitination of DNA damage-stalled RNAPII promotes transcription-coupled repair Y Nakazawa, Y Hara, Y Oka, O Komine, D van den Heuvel, C Guo, ... Cell 180 (6), 1228-1244. e24, 2020 | 205 | 2020 |
| Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis TM Miller, SH Kim, K Yamanaka, M Hester, P Umapathi, H Arnson, L Rizo, ... Proceedings of the National Academy of Sciences 103 (51), 19546-19551, 2006 | 199 | 2006 |
