| Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin K Kuboki, ZY Jiang, N Takahara, SW Ha, M Igarashi, T Yamauchi, ... Circulation 101 (6), 676-681, 2000 | 930 | 2000 |
| The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites TP Herbert, AR Tee, CG Proud Journal of Biological Chemistry 277 (13), 11591-11596, 2002 | 233 | 2002 |
| Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms AD Barlow, ML Nicholson, TP Herbert Diabetes 62 (8), 2674-2682, 2013 | 230 | 2013 |
| Identification of a protein linked to the genomic and subgenomic mRNAs of feline calicivirus and its role in translation. TP Herbert, I Brierley, TDK Brown Journal of General Virology 78 (5), 1033-1040, 1997 | 219 | 1997 |
| cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to … E Gomez, C Pritchard, TP Herbert Journal of Biological Chemistry 277 (50), 48146-48151, 2002 | 197 | 2002 |
| Rapid induction of apoptosis mediated by peptides that bind initiation factor eIF4E TP Herbert, R Fåhraeus, A Prescott, DP Lane, CG Proud Current Biology 10 (13), 793-796, 2000 | 132 | 2000 |
| Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation B Wicksteed, TP Herbert, C Alarcon, MK Lingohr, LG Moss, CJ Rhodes Journal of Biological Chemistry 276 (25), 22553-22558, 2001 | 122 | 2001 |
| Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells K Evans, Z Nasim, J Brown, H Butler, S Kauser, JD Erickson, TP Herbert, ... Journal of the American Society of Nephrology 18 (5), 1426-1436, 2007 | 116 | 2007 |
| Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells TP Herbert, GR Kilhams, IH Batty, CG Proud Journal of Biological Chemistry 275 (15), 11249-11256, 2000 | 114 | 2000 |
| Detection of the ORF3 polypeptide of feline calicivirus in infected cells and evidence for its expression from a single, functionally bicistronic, subgenomic mRNA TP Herbert, I Brierley, TDK Brown Journal of General Virology 77 (1), 123-127, 1996 | 104 | 1996 |
| Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2) AD Barlow, J Xie, CE Moore, SC Campbell, JAM Shaw, ML Nicholson, ... Diabetologia 55, 1355-1365, 2012 | 95 | 2012 |
| cAMP inhibits mammalian target of rapamycin complex-1 and-2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity J Xie, GA Ponuwei, CE Moore, GB Willars, AR Tee, TP Herbert Cellular signalling 23 (12), 1927-1935, 2011 | 87 | 2011 |
| The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes J Xie, TP Herbert Cellular and Molecular Life Sciences 69, 1289-1304, 2012 | 84 | 2012 |
| A reevaluation of the role of the unfolded protein response in islet dysfunction: maladaptation or a failure to adapt? TP Herbert, DR Laybutt Diabetes 65 (6), 1472-1480, 2016 | 81 | 2016 |
| A decrease in cellular energy status stimulates PERK-dependent eIF2α phosphorylation and regulates protein synthesis in pancreatic β-cells E Gomez, ML Powell, A Bevington, TP Herbert Biochemical Journal 410 (3), 485-493, 2008 | 78 | 2008 |
| PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells CE Moore, O Omikorede, E Gomez, GB Willars, TP Herbert Molecular Endocrinology 25 (2), 315-326, 2011 | 75 | 2011 |
| Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells C Chen, M Cano, JJ Wang, J Li, C Huang, Q Yu, TP Herbert, JT Handa, ... Antioxidants & Redox Signaling 20 (14), 2091-2106, 2014 | 71 | 2014 |
| Inhibition of SNAT2 by metabolic acidosis enhances proteolysis in skeletal muscle K Evans, Z Nasim, J Brown, E Clapp, A Amin, B Yang, TP Herbert, ... Journal of the American Society of Nephrology 19 (11), 2119-2129, 2008 | 71 | 2008 |
| Glucose-stimulated protein synthesis in pancreatic β-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP· Met-tRNAi) and the … E Gomez, ML Powell, IC Greenman, TP Herbert Journal of Biological Chemistry 279 (52), 53937-53946, 2004 | 64 | 2004 |
| Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic β-cells CEJ Moore, J Xie, E Gomez, TP Herbert Journal of molecular biology 389 (3), 480-494, 2009 | 61 | 2009 |
