| Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 RGW Verhaak, KA Hoadley, E Purdom, V Wang, Y Qi, MD Wilkerson, ... Cancer cell 17 (1), 98-110, 2010 | 8447 | 2010 |
| Comprehensive genomic characterization defines human glioblastoma genes and core pathways Cancer Genome Atlas Research Network Tissue source sites: Duke University ... Nature 455 (7216), 1061-1068, 2008 | 7655 | 2008 |
| Integrated genomic analyses of ovarian carcinoma Cancer Genome Atlas Research Network Nature 474 (7353), 609, 2011 | 5740 | 2011 |
| The somatic genomic landscape of glioblastoma CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ... cell 155 (2), 462-477, 2013 | 5377 | 2013 |
| Tumor mutational load predicts survival after immunotherapy across multiple cancer types RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ... Nature genetics 51 (2), 202-206, 2019 | 3509 | 2019 |
| Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas Cancer Genome Atlas Research Network New England Journal of Medicine 372 (26), 2481-2498, 2015 | 3112 | 2015 |
| Malignant astrocytic glioma: genetics, biology, and paths to treatment FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ... Genes & development 21 (21), 2683-2710, 2007 | 2987 | 2007 |
| CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2386 | 2013 |
| MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib J Bean, C Brennan, JY Shih, G Riely, A Viale, L Wang, D Chitale, N Motoi, ... Proceedings of the National Academy of Sciences 104 (52), 20932-20937, 2007 | 1991 | 2007 |
| Molecular characterization of the tumor microenvironment in breast cancer M Allinen, R Beroukhim, L Cai, C Brennan, J Lahti-Domenici, H Huang, ... Cancer cell 6 (1), 17-32, 2004 | 1597 | 2004 |
| Glioblastoma stem-like cells give rise to tumour endothelium R Wang, K Chadalavada, J Wilshire, U Kowalik, KE Hovinga, A Geber, ... Nature 468 (7325), 829-833, 2010 | 1494 | 2010 |
| An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ... Science 340 (6132), 626-630, 2013 | 1323 | 2013 |
| A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle MF Kircher, A De La Zerda, JV Jokerst, CL Zavaleta, PJ Kempen, E Mittra, ... Nature medicine 18 (5), 829-834, 2012 | 1211 | 2012 |
| Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ... Science 318 (5848), 287-290, 2007 | 1130 | 2007 |
| PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells AM Bleau, D Hambardzumyan, T Ozawa, EI Fomchenko, JT Huse, ... Cell stem cell 4 (3), 226-235, 2009 | 975 | 2009 |
| Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis L Busque, JP Patel, ME Figueroa, A Vasanthakumar, S Provost, ... Nature genetics 44 (11), 1179-1181, 2012 | 929 | 2012 |
| Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO VE Clark, EZ Erson-Omay, A Serin, J Yin, J Cotney, K Özduman, T Avşar, ... Science 339 (6123), 1077-1080, 2013 | 911 | 2013 |
| p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Nature 455 (7216), 1129-1133, 2008 | 889 | 2008 |
| Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ... Cell 181 (7), 1643-1660. e17, 2020 | 819 | 2020 |
| Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse N Bardeesy, AJ Aguirre, GC Chu, K Cheng, LV Lopez, AF Hezel, B Feng, ... Proceedings of the National Academy of Sciences 103 (15), 5947-5952, 2006 | 757 | 2006 |
