Phospholipase PLA2G6, a parkinsonism-associated gene, affects Vps26 and Vps35, retromer function, and ceramide levels, similar to α-synuclein gain G Lin, PT Lee, K Chen, D Mao, KL Tan, Z Zuo, WW Lin, L Wang, HJ Bellen Cell metabolism 28 (4), 605-618. e6, 2018 | 167 | 2018 |
Parallel early development of zebrafish interrenal glands and pronephros:differential control by wt1 and ff1b HJ Hsu, G Lin, B Chung Oxford University Press for The Company of Biologists Limited 130 (10), 2107 …, 2003 | 130 | 2003 |
Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification M Şentürk, G Lin, Z Zuo, D Mao, E Watson, AG Mikos, HJ Bellen Nature cell biology 21 (3), 384-396, 2019 | 123 | 2019 |
Sphingolipids in the Pathogenesis of Parkinson’s Disease and Parkinsonism G Lin, L Wang, PC Marcogliese, HJ Bellen Trends in Endocrinology & Metabolism 30 (2), 106-117, 2019 | 112 | 2019 |
Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the ‘PTP-ome' G Lin, V Aranda, SK Muthuswamy, NK Tonks Genes & development 25 (13), 1412-1425, 2011 | 85 | 2011 |
Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration K Chen, G Lin, NA Haelterman, TSY Ho, T Li, Z Li, L Duraine, BH Graham, ... Elife 5, e16043, 2016 | 80 | 2016 |
Cyclic AMP stimulates SF-1-dependent CYP11A1 expression through homeodomain-interacting protein kinase 3-mediated Jun N-terminal kinase and c-Jun phosphorylation HC Lan, HJ Li, G Lin, PY Lai, B Chung Molecular and cellular biology 27 (6), 2027-2036, 2007 | 78 | 2007 |
Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals K Chen, TSY Ho, G Lin, KL Tan, MN Rasband, HJ Bellen Elife 5, e20732, 2016 | 70 | 2016 |
VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway D Mao, G Lin, B Tepe, Z Zuo, KL Tan, M Senturk, S Zhang, BR Arenkiel, ... Autophagy 15 (7), 1214-1233, 2019 | 65 | 2019 |
Protein-tyrosine Phosphatase 1B Antagonized Signaling by Insulin-like Growth Factor-1 Receptor and Kinase BRK/PTK6 in Ovarian Cancer Cells*♦ G Fan, G Lin, R Lucito, NK Tonks Journal of Biological Chemistry 288 (34), 24923-24934, 2013 | 61 | 2013 |
Ari-1 regulates myonuclear organization together with parkin and is associated with aortic aneurysms KL Tan, NA Haelterman, CS Kwartler, ES Regalado, PT Lee, ... Developmental cell 45 (2), 226-244. e8, 2018 | 59 | 2018 |
Cold‐induced ependymin expression in zebrafish and carp brain: implications for cold acclimation SJ Tang, KH Sun, GH Sun, G Lin, WW Lin, MJ Chuang FEBS letters 459 (1), 95-99, 1999 | 54 | 1999 |
Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformation M Yu, G Lin, N Arshadi, I Kalatskaya, B Xue, S Haider, F Nguyen, ... Molecular and cellular biology 32 (19), 3913-3924, 2012 | 49 | 2012 |
Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia L Wang, G Lin, Z Zuo, Y Li, SK Byeon, A Pandey, HJ Bellen Science advances 8 (28), eabn3326, 2022 | 36 | 2022 |
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation PT Lee, G Lin, WW Lin, F Diao, BH White, HJ Bellen Elife 7, e33007, 2018 | 36 | 2018 |
Amyotrophic lateral sclerosis pathogenesis converges on defects in protein homeostasis associated with TDP-43 mislocalization and proteasome-mediated degradation overload G Lin, D Mao, HJ Bellen Current topics in developmental biology 121, 111-171, 2017 | 30 | 2017 |
Ubr3, a novel modulator of Hh signaling affects the degradation of Costal-2 and Kif7 through poly-ubiquitination T Li, J Fan, B Blanco-Sánchez, N Giagtzoglou, G Lin, S Yamamoto, ... PLoS Genetics 12 (5), e1006054, 2016 | 19 | 2016 |
Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14) G Lin, B Tepe, G McGrane, RC Tipon, G Croft, L Panwala, A Hope, ... Elife 12, e82555, 2023 | 11 | 2023 |
A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels D Dutta, O Kanca, SK Byeon, PC Marcogliese, Z Zuo, RV Shridharan, ... Nature metabolism 5 (9), 1595-1614, 2023 | 10 | 2023 |
Expression, purification, refolding, and characterization of recombinant human soluble-Fas ligand from Escherichia coli KH Sun, GH Sun, CY Tsai, HH Wang, C Chung, G Lin, WW Lin, SJ Tang Enzyme and microbial technology 36 (4), 527-534, 2005 | 7 | 2005 |