| Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding SG Aller, J Yu, A Ward, Y Weng, S Chittaboina, R Zhuo, PM Harrell, ... science 323 (5922), 1718-1722, 2009 | 2423 | 2009 |
| Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability PJM Brouwer, TG Caniels, K van der Straten, JL Snitselaar, Y Aldon, ... Science 369 (6504), 643-650, 2020 | 1262 | 2020 |
| Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen J Pallesen, N Wang, KS Corbett, D Wrapp, RN Kirchdoerfer, HL Turner, ... Proceedings of the National Academy of Sciences 114 (35), E7348-E7357, 2017 | 1187 | 2017 |
| SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2 TM Clausen, DR Sandoval, CB Spliid, J Pihl, HR Perrett, CD Painter, ... Cell 183 (4), 1043-1057. e15, 2020 | 1168 | 2020 |
| Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ... Nature 480 (7377), 336-343, 2011 | 1059 | 2011 |
| A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP. 664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies RW Sanders, R Derking, A Cupo, JP Julien, A Yasmeen, N de Val, HJ Kim, ... PLoS pathogens 9 (9), e1003618, 2013 | 1041 | 2013 |
| Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors RN Kirchdoerfer, AB Ward Nature communications 10 (1), 2342, 2019 | 984 | 2019 |
| Flexibility in the ABC transporter MsbA: Alternating access with a twist A Ward, CL Reyes, J Yu, CB Roth, G Chang Proceedings of the National Academy of Sciences 104 (48), 19005-19010, 2007 | 974 | 2007 |
| Crystal structure of a soluble cleaved HIV-1 envelope trimer JP Julien, A Cupo, D Sok, RL Stanfield, D Lyumkis, MC Deller, PJ Klasse, ... Science 342 (6165), 1477-1483, 2013 | 973 | 2013 |
| Pre-fusion structure of a human coronavirus spike protein RN Kirchdoerfer, CA Cottrell, N Wang, J Pallesen, HM Yassine, HL Turner, ... Nature 531 (7592), 118-121, 2016 | 886 | 2016 |
| A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield R Pejchal, KJ Doores, LM Walker, R Khayat, PS Huang, SK Wang, ... Science 334 (6059), 1097-1103, 2011 | 886 | 2011 |
| Highly conserved protective epitopes on influenza B viruses C Dreyfus, NS Laursen, T Kwaks, D Zuijdgeest, R Khayat, DC Ekiert, ... Science 337 (6100), 1343-1348, 2012 | 880 | 2012 |
| Rational HIV immunogen design to target specific germline B cell receptors J Jardine, JP Julien, S Menis, T Ota, O Kalyuzhniy, A McGuire, D Sok, ... Science 340 (6133), 711-716, 2013 | 844 | 2013 |
| Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer D Lyumkis, JP Julien, N De Val, A Cupo, CS Potter, PJ Klasse, DR Burton, ... Science 342 (6165), 1484-1490, 2013 | 818 | 2013 |
| Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ... Nature 509 (7498), 55-62, 2014 | 813 | 2014 |
| A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen A Impagliazzo, F Milder, H Kuipers, MV Wagner, X Zhu, RMB Hoffman, ... Science 349 (6254), 1301-1306, 2015 | 628 | 2015 |
| HIV-1 neutralizing antibodies induced by native-like envelope trimers RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ... Science 349 (6244), aac4223, 2015 | 561 | 2015 |
| Structure of the mechanically activated ion channel Piezo1 K Saotome, SE Murthy, JM Kefauver, T Whitwam, A Patapoutian, AB Ward Nature 554 (7693), 481-486, 2018 | 557 | 2018 |
| Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp, HL Turner, CA Cottrell, ... Scientific reports 8 (1), 15701, 2018 | 550 | 2018 |
| Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ... Nature 515 (7525), 138-142, 2014 | 520 | 2014 |
PJ KlasseProfessor of Microbiology and Immunology, Cornell UniversityEmail được xác minh tại med.cornell.edu
