Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ... Journal of Biological Chemistry 280 (10), 9547-9554, 2005 | 152 | 2005 |
Evolution of Enzymatic Activity in the Enolase Superfamily: Structure of o-Succinylbenzoate Synthase from Escherichia coli in Complex with Mg2+ and o-Succinylbenzoate … TB Thompson, JB Garrett, EA Taylor, R Meganathan, JA Gerlt, I Rayment Biochemistry 39 (35), 10662-10676, 2000 | 92 | 2000 |
Methyl transfer by substrate signaling from a knotted protein fold T Christian, R Sakaguchi, AP Perlinska, G Lahoud, T Ito, EA Taylor, ... Nature structural & molecular biology 23 (10), 941-948, 2016 | 90 | 2016 |
Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases K Clinch, GB Evans, GWJ Fleet, RH Furneaux, SW Johnson, DH Lenz, ... Organic & Biomolecular Chemistry 4 (6), 1131-1139, 2006 | 83 | 2006 |
Evolution of Enzymatic Activity in the Enolase Superfamily: Functional Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis EA Taylor Ringia, JB Garrett, JB Thoden, HM Holden, I Rayment, JA Gerlt Biochemistry 43 (1), 224-229, 2004 | 74 | 2004 |
Energetic Mapping of Transition State Analogue Interactions with Human and Plasmodium falciparum Purine Nucleoside Phosphorylases*♦ A Lewandowicz, EAT Ringia, LM Ting, K Kim, PC Tyler, GB Evans, ... Journal of Biological Chemistry 280 (34), 30320-30328, 2005 | 70 | 2005 |
Characterizing the Promiscuity of LigAB, a Lignin Catabolite Degrading Extradiol Dioxygenase from Sphingomonas paucimobilis SYK-6 KP Barry, EA Taylor Biochemistry 52 (38), 6724-6736, 2013 | 69 | 2013 |
Synthesis of 5 ‘-methylthio coformycins: Specific inhibitors for malarial adenosine deaminase PC Tyler, EA Taylor, RFG Fröhlich, VL Schramm Journal of the American Chemical Society 129 (21), 6872-6879, 2007 | 69 | 2007 |
Neighboring group participation in the transition state of human purine nucleoside phosphorylase AS Murkin, MR Birck, A Rinaldo-Matthis, W Shi, EA Taylor, VL Schramm Biochemistry 46 (17), 5038-5049, 2007 | 68 | 2007 |
Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis, JB Thoden, EA Taylor Ringia, JB Garrett, JA Gerlt, HM Holden, I Rayment Biochemistry 43 (19), 5716-5727, 2004 | 67 | 2004 |
Acyclic ribooxacarbenium ion mimics as transition state analogues of human and malarial purine nucleoside phosphorylases EA Taylor, K Clinch, PM Kelly, L Li, GB Evans, PC Tyler, VL Schramm Journal of the American Chemical Society 129 (22), 6984-6985, 2007 | 52 | 2007 |
Transition states and inhibitors of the purine nucleoside phosphorylase family EAT Ringia, VL Schramm Current topics in medicinal chemistry 5 (13), 1237-1258, 2005 | 52 | 2005 |
The glycosyltransferases of LPS core: a review of four heptosyltransferase enzymes in context JM Cote, EA Taylor International journal of molecular sciences 18 (11), 2256, 2017 | 50 | 2017 |
The Lesser “Burden Borne” by o-Succinylbenzoate Synthase: An “Easy” Reaction Involving a Carboxylate Carbon Acid EA Taylor, DRJ Palmer, JA Gerlt Journal of the American Chemical Society 123 (24), 5824-5825, 2001 | 50 | 2001 |
Transition-State Variation in Human, Bovine, and Plasmodium falciparum Adenosine Deaminases M Luo, V Singh, EA Taylor, VL Schramm Journal of the American Chemical Society 129 (25), 8008-8017, 2007 | 44 | 2007 |
Evolution of enzymatic activity in the enolase superfamily: structural and mutagenic studies of the mechanism of the reaction catalyzed by o-succinylbenzoate synthase from … VA Klenchin, EA Taylor Ringia, JA Gerlt, I Rayment Biochemistry 42 (49), 14427-14433, 2003 | 44 | 2003 |
Transition state analogue discrimination by related purine nucleoside phosphorylases EA Taylor Ringia, PC Tyler, GB Evans, RH Furneaux, AS Murkin, ... Journal of the American Chemical Society 128 (22), 7126-7127, 2006 | 42 | 2006 |
Hydrophobic interactions of sucralose with protein structures N Shukla, E Pomarico, CJS Hecht, EA Taylor, M Chergui, CM Othon Archives of biochemistry and biophysics 639, 38-43, 2018 | 29 | 2018 |
Lipopolysaccharide Biosynthesis without the Lipids: Recognition Promiscuity of Escherichia coli Heptosyltransferase I DJ Czyzyk, C Liu, EA Taylor Biochemistry 50 (49), 10570-10572, 2011 | 29 | 2011 |
Oxidative opening of the aromatic ring: Tracing the natural history of a large superfamily of dioxygenase domains and their relatives AM Burroughs, ME Glasner, KP Barry, EA Taylor, L Aravind Journal of Biological Chemistry 294 (26), 10211-10235, 2019 | 25 | 2019 |