| Multi-target approach for natural products in inflammation A Koeberle, O Werz Drug discovery today 19 (12), 1871-1882, 2014 | 335 | 2014 |
| Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1 A Koeberle, U Siemoneit, U Bühring, H Northoff, S Laufer, W Albrecht, ... The Journal of pharmacology and experimental therapeutics 326 (3), 975-982, 2008 | 210 | 2008 |
| Inhibition of microsomal prostaglandin E2 synthase‐1 as a molecular basis for the anti‐inflammatory actions of boswellic acids from frankincense U Siemoneit, A Koeberle, A Rossi, F Dehm, M Verhoff, S Reckel, TJ Maier, ... British journal of pharmacology 162 (1), 147-162, 2011 | 162 | 2011 |
| The 5‐lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages A Rossi, C Pergola, A Koeberle, M Hoffmann, F Dehm, P Bramanti, ... British journal of pharmacology 161 (3), 555-570, 2010 | 157 | 2010 |
| Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo A Rossi, R Di Paola, E Mazzon, T Genovese, R Caminiti, P Bramanti, ... The journal of pharmacology and experimental therapeutics 329 (1), 76-86, 2009 | 157 | 2009 |
| Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders A Koeberle, O Werz Biochemical pharmacology 98 (1), 1-15, 2015 | 155 | 2015 |
| Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1 A Koeberle, H Northoff, O Werz Molecular cancer therapeutics 8 (8), 2348-2355, 2009 | 151 | 2009 |
| Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1 J Bauer, S Kuehnl, JM Rollinger, O Scherer, H Northoff, H Stuppner, ... The Journal of pharmacology and experimental therapeutics 342 (1), 169-176, 2012 | 149 | 2012 |
| Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor SC Koeberle, J Romir, S Fischer, A Koeberle, V Schattel, W Albrecht, ... Nature chemical biology 8 (2), 141-143, 2012 | 147 | 2012 |
| Inhibitors of the microsomal prostaglandin E2 synthase-1 as alternative to non steroidal anti-inflammatory drugs (NSAIDs)-a critical review A Koeberle, O Werz Current medicinal chemistry 16 (32), 4274-4296, 2009 | 147 | 2009 |
| Revealing the macromolecular targets of complex natural products D Reker, AM Perna, T Rodrigues, P Schneider, M Reutlinger, B Mönch, ... Nature chemistry 6 (12), 1072-1078, 2014 | 140 | 2014 |
| Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase O Werz, J Seegers, AM Schaible, C Weinigel, D Barz, A Koeberle, ... PharmaNutrition 2 (3), 53-60, 2014 | 139 | 2014 |
| Pirinixic Acid Derivatives as Novel Dual Inhibitors of Microsomal Prostaglandin E2 Synthase-1 and 5-Lipoxygenase A Koeberle, H Zettl, C Greiner, M Wurglics, M Schubert-Zsilavecz, O Werz Journal of medicinal chemistry 51 (24), 8068-8076, 2008 | 137 | 2008 |
| Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase H Pein, A Ville, S Pace, V Temml, U Garscha, M Raasch, K Alsabil, ... Nature communications 9 (1), 3834, 2018 | 134 | 2018 |
| Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo J Bauer, A Koeberle, F Dehm, F Pollastro, G Appendino, H Northoff, ... Biochemical pharmacology 81 (2), 259-268, 2011 | 130 | 2011 |
| Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol A Koeberle, H Northoff, O Werz Biochemical pharmacology 77 (9), 1513-1521, 2009 | 124 | 2009 |
| Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome M Werner, PM Jordan, E Romp, A Czapka, Z Rao, C Kretzer, A Koeberle, ... The FASEB Journal 33 (5), 6140, 2019 | 117 | 2019 |
| Myrtucommulone, a natural acylphloroglucinol, inhibits microsomal prostaglandin E2 synthase‐1 A Koeberle, F Pollastro, H Northoff, O Werz British journal of pharmacology 156 (6), 952-961, 2009 | 113 | 2009 |
| Hyperforin, an anti-inflammatory constituent from St. John's wort, inhibits microsomal prostaglandin E2 synthase-1 and suppresses prostaglandin E2 formation in vivo A Koeberle, A Rossi, J Bauer, F Dehm, L Verotta, H Northoff, L Sautebin, ... Frontiers in pharmacology 2, 7, 2011 | 109 | 2011 |
| Docosahexaenoic acid in the treatment of rheumatoid arthritis: A double-blind, placebo-controlled, randomized cross-over study with microalgae vs. sunflower oil C Dawczynski, M Dittrich, T Neumann, K Goetze, A Welzel, P Oelzner, ... Clinical Nutrition 37 (2), 494-504, 2018 | 102 | 2018 |
