Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders K Singh, M Jayaram, M Kaare, E Leidmaa, T Jagomäe, I Heinla, ... Scientific Reports 9 (1), 5457, 2019 | 62 | 2019 |
Wfs1-deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration M Plaas, K Seppa, R Reimets, T Jagomäe, M Toots, T Koppel, T Vallisoo, ... Scientific reports 7 (1), 10220, 2017 | 58 | 2017 |
GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome K Seppa, M Toots, R Reimets, T Jagomäe, T Koppel, M Pallase, ... Scientific Reports 9 (1), 15742, 2019 | 44 | 2019 |
Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome M Toots, K Seppa, T Jagomäe, T Koppel, M Pallase, I Heinla, A Terasmaa, ... Scientific reports 8 (1), 10183, 2018 | 41 | 2018 |
Liraglutide, 7, 8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model K Seppa, T Jagomäe, KG Kukker, R Reimets, M Pastak, E Vasar, ... Scientific Reports 11 (1), 2275, 2021 | 28 | 2021 |
Early intervention and lifelong treatment with GLP1 receptor agonist liraglutide in a wolfram syndrome rat model with an emphasis on visual neurodegeneration, sensorineural … T Jagomäe, K Seppa, R Reimets, M Pastak, M Plaas, MA Hickey, ... Cells 10 (11), 3193, 2021 | 22 | 2021 |
Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system A Bregin, M Kaare, T Jagomäe, K Karis, K Singh, K Laugus, J Innos, ... Pharmacology Biochemistry and Behavior 198, 173017, 2020 | 15 | 2020 |
High-fat diet induces pre-diabetes and distinct sex-specific metabolic alterations in Negr1-deficient mice M Kaare, K Mikheim, K Lilleväli, K Kilk, T Jagomäe, E Leidmaa, M Piirsalu, ... Biomedicines 9 (9), 1148, 2021 | 13 | 2021 |
Alternative promoter use governs the expression of IgLON cell adhesion molecules in histogenetic fields of the embryonic mouse brain T Jagomäe, K Singh, MA Philips, M Jayaram, K Seppa, T Tekko, ... International Journal of Molecular Sciences 22 (13), 6955, 2021 | 12 | 2021 |
Chronic alcohol use induces molecular genetic changes in the dorsomedial thalamus of people with alcohol-related disorders AC Hade, MA Philips, E Reimann, T Jagomäe, KL Eskla, T Traks, E Prans, ... Brain Sciences 11 (4), 435, 2021 | 10 | 2021 |
Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors T Tekko, T Lakspere, A Allikalt, J End, KR Kolvart, T Jagomäe, ... PloS one 12 (3), e0172825, 2017 | 8 | 2017 |
Hypothermia alleviates reductive stress, a root cause of ischemia reperfusion injury KL Eskla, H Vellama, L Tarve, H Eichelmann, T Jagomäe, R Porosk, V Oja, ... International Journal of Molecular Sciences 23 (17), 10108, 2022 | 7 | 2022 |
Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to … M Kaare, M Jayaram, T Jagomäe, K Singh, K Kilk, K Mikheim, M Leevik, ... Brain Sciences 12 (12), 1696, 2022 | 6 | 2022 |
Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome T Jagomäe, N Gaur, K Seppa, R Reimets, M Pastak, M Plaas, A Kaasik, ... Frontiers in Endocrinology 14, 1234925, 2023 | 3 | 2023 |
The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome M Punapart, K Seppa, T Jagomäe, M Liiv, R Reimets, S Kirillov, A Kaasik, ... Genes 12 (11), 1717, 2021 | 3 | 2021 |
High‐throughput proteomic analysis of chronic inflammatory skin diseases: Psoriasis and atopic dermatitis T Traks, P Reemann, KL Eskla, A Ottas, T Jagomäe, R Liira, L Ilves, ... Experimental Dermatology 33 (4), e15079, 2024 | 2 | 2024 |
A cost-effective and efficient ex vivo, ex situ human whole brain perfusion protocol for immunohistochemistry AC Hade, MA Philips, L Promet, T Jagomäe, A Hanumantharaju, ... Journal of Neuroscience Methods 404, 110059, 2024 | 2 | 2024 |
Chronic stress alters hippocampal renin-angiotensin-aldosterone system component expression in an aged rat model of wolfram syndrome M Punapart, R Reimets, K Seppa, S Kirillov, N Gaur, KL Eskla, T Jagomäe, ... Genes 14 (4), 827, 2023 | 2 | 2023 |
VHL-deficiency leads to reductive stress in renal cells H Vellama, KL Eskla, H Eichelmann, A Hüva, DA Tennant, A Thakker, ... Free Radical Biology and Medicine 208, 1-12, 2023 | 1 | 2023 |
GABA and GLP-1 receptor agonist combination therapy modifies diabetes and Langerhans islet cytoarchitecture in a rat model of Wolfram syndrome T Jagomäe, S Velling, TB Tikva, V Maksimtšuk, N Gaur, R Reimets, ... Diabetology & Metabolic Syndrome 17 (1), 1-15, 2025 | | 2025 |