A high-resolution map of human evolutionary constraint using 29 mammals K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ... Nature 478 (7370), 476-482, 2011 | 1283 | 2011 |
Regulatory networks define phenotypic classes of human stem cell lines FJ Müller, LC Laurent, D Kostka, I Ulitsky, R Williams, C Lu, IH Park, ... Nature 455 (7211), 401-405, 2008 | 400 | 2008 |
Gibbon genome and the fast karyotype evolution of small apes L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ... Nature 513 (7517), 195-201, 2014 | 386 | 2014 |
scds: Computational annotation of doublets in single-cell RNA sequencing data AS Bais, D Kostka Bioinformatics 36 (4), btz968, 2019 | 242 | 2019 |
The complex genetics of hypoplastic left heart syndrome X Liu, H Yagi, S Saeed, AS Bais, GC Gabriel, Z Chen, KA Peterson, Y Li, ... Nature genetics 49 (7), 1152-1159, 2017 | 226 | 2017 |
Integrating diverse datasets improves developmental enhancer prediction GD Erwin, N Oksenberg, RM Truty, D Kostka, KK Murphy, N Ahituv, ... PLoS computational biology 10 (6), e1003677, 2014 | 188 | 2014 |
Finding disease specific alterations in the co-expression of genes D Kostka, R Spang Bioinformatics 20 (suppl_1), i194-i199, 2004 | 188 | 2004 |
Nested effects models for high-dimensional phenotyping screens F Markowetz, D Kostka, OG Troyanskaya, R Spang Bioinformatics 23 (13), i305-i312, 2007 | 130 | 2007 |
The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome D Kostka, MJ Hubisz, A Siepel, KS Pollard Molecular biology and evolution 29 (3), 1047-1057, 2012 | 113 | 2012 |
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment H Liu, CH Zhang, N Ammanamanchi, S Suresh, C Lewarchik, K Rao, ... Science translational medicine 11 (513), eaaw6419, 2019 | 97 | 2019 |
MicroRNA-17~ 92 is required for nephrogenesis and renal function AK Marrone, DB Stolz, SI Bastacky, D Kostka, AJ Bodnar, J Ho Journal of the American Society of Nephrology 25 (7), 1440-1452, 2014 | 87 | 2014 |
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans FRG Amrit, EM Steenkiste, R Ratnappan, SW Chen, TB McClendon, ... PLoS genetics 12 (2), e1005788, 2016 | 82 | 2016 |
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes JA Capra, MJ Hubisz, D Kostka, KS Pollard, A Siepel PLoS genetics 9 (8), e1003684, 2013 | 82 | 2013 |
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity DI Ritter, Q Li, D Kostka, KS Pollard, S Guo, JH Chuang Molecular biology and evolution 27 (10), 2322-2332, 2010 | 65 | 2010 |
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia R Kirschner-Schwabe, C Lottaz, J Tödling, P Rhein, L Karawajew, ... Clinical cancer research 12 (15), 4553-4561, 2006 | 61 | 2006 |
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function ML Benton, SC Talipineni, D Kostka, JA Capra Bmc Genomics 20, 1-22, 2019 | 58 | 2019 |
Random forest based similarity learning for single cell RNA sequencing data MB Pouyan, D Kostka Bioinformatics, 34 (13), i79–i88, 2018 | 57 | 2018 |
Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease X Xu, K Jin, AS Bais, W Zhu, H Yagi, TN Feinstein, PK Nguyen, ... Cell Stem Cell, 2022 | 54 | 2022 |
Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages W Feng, A Bais, H He, C Rios, S Jiang, J Xu, C Chang, D Kostka, G Li Nature Communications 13 (1), 7960, 2022 | 46 | 2022 |
Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency W Feng, H Schriever, S Jiang, A Bais, H Wu, D Kostka, G Li Communications Biology 5 (1), 399, 2022 | 45 | 2022 |