Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease EA Newcombe, J Camats-Perna, ML Silva, N Valmas, TJ Huat, ... Journal of neuroinflammation 15, 1-26, 2018 | 552 | 2018 |
Metal toxicity links to Alzheimer's disease and neuroinflammation TJ Huat, J Camats-Perna, EA Newcombe, N Valmas, M Kitazawa, ... Journal of molecular biology 431 (9), 1843-1868, 2019 | 446 | 2019 |
Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles S Hennig, G Kong, T Mannen, A Sadowska, S Kobelke, A Blythe, GJ Knott, ... Journal of Cell Biology 210 (4), 529-539, 2015 | 340 | 2015 |
Huntingtin inclusions trigger cellular quiescence, deactivate apoptosis, and lead to delayed necrosis YM Ramdzan, MM Trubetskov, AR Ormsby, EA Newcombe, X Sui, ... Cell reports 19 (5), 919-927, 2017 | 117 | 2017 |
Tadpole-like conformations of huntingtin exon 1 are characterized by conformational heterogeneity that persists regardless of polyglutamine length EA Newcombe, KM Ruff, A Sethi, AR Ormsby, YM Ramdzan, A Fox, ... Journal of molecular biology 430 (10), 1442-1458, 2018 | 72 | 2018 |
Refinement of α-synuclein ensembles against SAXS data: Comparison of force fields and methods MC Ahmed, LK Skaanning, A Jussupow, EA Newcombe, BB Kragelund, ... Frontiers in molecular biosciences 8, 654333, 2021 | 61 | 2021 |
How phosphorylation impacts intrinsically disordered proteins and their function EA Newcombe, E Delaforge, R Hartmann-Petersen, K Skriver, ... Essays in Biochemistry 66 (7), 901-913, 2022 | 59 | 2022 |
Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells S Büning, A Sharma, S Vachharajani, E Newcombe, A Ormsby, M Gao, ... Physical Chemistry Chemical Physics 19 (17), 10738-10747, 2017 | 30 | 2017 |
Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins F Pesce, EA Newcombe, P Seiffert, EE Tranchant, JG Olsen, CR Grace, ... Biophysical Journal 122 (2), 310-321, 2023 | 26 | 2023 |
EphA4 Regulates Hippocampal Neural Precursor Proliferation in the Adult Mouse Brain by d-Serine Modulation of N-Methyl-d-Aspartate Receptor Signaling J Zhao, CJ Taylor, EA Newcombe, MD Spanevello, I O’Keeffe, LT Cooper, ... Cerebral Cortex 29 (10), 4381-4397, 2019 | 22 | 2019 |
Insight into calcium-binding motifs of intrinsically disordered proteins EA Newcombe, CB Fernandes, JE Lundsgaard, I Brakti, K Lindorff-Larsen, ... Biomolecules 11 (8), 1173, 2021 | 21 | 2021 |
Deciphering the alphabet of disorder—Glu and Asp act differently on local but not global properties MA Roesgaard, JE Lundsgaard, EA Newcombe, NL Jacobsen, F Pesce, ... Biomolecules 12 (10), 1426, 2022 | 16 | 2022 |
The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains T Jong Huat, J Camats-Perna, EA Newcombe, T Onraet, D Campbell, ... Scientific Reports 14 (1), 14305, 2024 | 12 | 2024 |
Monomeric α‐synuclein activates the plasma membrane calcium pump A Kowalski, C Betzer, ST Larsen, E Gregersen, EA Newcombe, ... The EMBO journal 42 (23), e111122, 2023 | 9 | 2023 |
Stereochemistry in the disorder–order continuum of protein interactions EA Newcombe, AD Due, A Sottini, S Elkjær, FF Theisen, CB Fernandes, ... Nature, 1-7, 2024 | 5 | 2024 |
Deletion of MyD88 in astrocytes prevents β‐amyloid‐induced neuropathology in mice T Jong Huat, T Onraet, J Camats‐Perna, EA Newcombe, KC Ngo, AN Sue, ... Glia 71 (2), 431-449, 2023 | 5 | 2023 |
The importance of stereochemistry in the disorder-order continuum of protein-protein interactions EA Newcombe, AD Due, A Sottini, CB Fernandes, L Staby, E Delaforge, ... bioRxiv, 2024.02. 23.581681, 2024 | 1 | 2024 |
Understanding the biology of Huntington's disease via the pathogenic huntingtin monomer E Newcombe, Y Ramdzan, A Sethi, M Lee, D Loo, B Graham, J Swarbrick, ... Protein Science 24, 86-87, 2015 | 1 | 2015 |
Targeted imaging of uPAR expression in vivo with cyclic AE105 variants JM Leth, EA Newcombe, AL Grønnemose, JT Jørgensen, K Qvist, ... Scientific Reports 13 (1), 17248, 2023 | | 2023 |
Enhancing the understanding of Huntington’s disease via structural and functional characterisation of the huntingtin monomer E Newcombe University of Melbourne, 2017 | | 2017 |